11β-Hydroxysteroid Dehydrogenase Type 2 Deficiency Accelerates Atherogenesis and Causes Proinflammatory Changes in the Endothelium in Apoe−/− Mice von Deuchar, Graeme A, McLean, Danielle, Hadoke, Patrick W. F, Brownstein, David G, Webb, David J, Mullins, John J, Chapman, Karen, Seckl, Jonathan R, Kotelevtsev, Yuri V

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ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice von Jones, Frances E, Bailey, Matthew A, Murray, Lydia S, Lu, Yinhui, McNeilly, Sarah, Schlötzer-Schrehardt, Ursula, Lennon, Rachel, Sado, Yoshikazu, Brownstein, David G, Mullins, John J, Kadler, Karl E, Van Agtmael, Tom

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Disruption of Ledgf/Psip1 Results in Perinatal Mortality and Homeotic Skeletal Transformations von Sutherland, Heidi G., Newton, Kathryn, Brownstein, David G., Holmes, Megan C., Kress, Clémence, Semple, Colin A., Bickmore, Wendy A.

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Dominant mutations of Col4a1 result in basement membrane defects which lead to anterior segment dysgenesis and glomerulopathy von Van Agtmael, Tom, Schlötzer-Schrehardt, Ursula, McKie, Lisa, Brownstein, David G., Lee, Angela W., Cross, Sally H., Sado, Yoshikazu, Mullins, John J., Pöschl, Ernst, Jackson, Ian J.

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Mast cells express 11β-hydroxysteroid dehydrogenase type 1: a role in restraining mast cell degranulation von Coutinho, Agnes E, Brown, Jeremy K, Yang, Fu, Brownstein, David G, Gray, Mohini, Seckl, Jonathan R, Savill, John S, Chapman, Karen E

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Cyp11b1 Null Mouse, a Model of Congenital Adrenal Hyperplasia von Mullins, Linda J., Peter, Audrey, Wrobel, Nicola, McNeilly, Judith R., McNeilly, Alan S., Al-Dujaili, Emad A.S., Brownstein, David G., Mullins, John J., Kenyon, Christopher J.

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Glucocorticoid receptor is required for foetal heart maturation von Rog-Zielinska, Eva A, Thomson, Adrian, Kenyon, Christopher J, Brownstein, David G, Moran, Carmel M, Szumska, Dorota, Michailidou, Zoi, Richardson, Jennifer, Owen, Elizabeth, Watt, Alistair, Morrison, Harris, Forrester, Lesley M, Bhattacharya, Shoumo, Holmes, Megan C, Chapman, Karen E

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A Switch in the Mechanism of Hypertension in the Syndrome of Apparent Mineralocorticoid Excess von BAILEY, Matthew A, PATERSON, Janice M, HADOKE, Patrick W. F, WROBEL, Nicola, BELLAMY, Christopher O. C, BROWNSTEIN, David G, SECKL, Jonathan R, MULLINS, John J

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11β-Hydroxysteroid Dehydrogenase Type 1, But Not Type 2, Deficiency Worsens Acute Inflammation and Experimental Arthritis in Mice von Coutinho, Agnes E, Gray, Mohini, Brownstein, David G, Salter, Donald M, Sawatzky, Deborah A, Clay, Spike, Gilmour, James S, Seckl, Jonathan R, Savill, John S, Chapman, Karen E

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Mutationally activated K- ras 4A and 4B both mediate lung carcinogenesis von Patek, Charles E., Arends, Mark J., Wallace, William A.H., Luo, Feijun, Hagan, Suzanne, Brownstein, David G., Rose, Lorraine, Devenney, Paul S., Walker, Marion, Plowman, Sarah J., Berry, Rachel L., Kolch, Walter, Sansom, Owen J., Harrison, David J., Hooper, Martin L.

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Col4a1 mutation in mice causes defects in vascular function and low blood pressure associated with reduced red blood cell volume von Van Agtmael, Tom, Bailey, Matthew A., Schlötzer-Schrehardt, Ursula, Craigie, Eilidh, Jackson, Ian J., Brownstein, David G., Megson, Ian L., Mullins, John J.

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Expression of the neuroprotective slow Wallerian degeneration (WldS) gene in non-neuronal tissues von Wishart, Thomas M, Brownstein, David G, Thomson, Derek, Tabakova, Anca M, Boothe, Katherine M, Tsao, Jack W, Gillingwater, Thomas H

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Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction von Xu, Tian, St John, Maie A R, Tao, Wufan, Fei, Xiaolan, Fukumoto, Royd, Carcangiu, Maria Luisa, Brownstein, David G, Parlow, Albert F, McGrath, James

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Mice with DNA repair gene Ercc1 deficiency in a neural crest lineage are a model for late-onset Hirschsprung disease von Selfridge, Jim, Song, Liang, Brownstein, David G., Melton, David W.

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Real-Time Visualization of Human Prolactin Alternate Promoter Usage in Vivo Using a Double-Transgenic Rat Model von Semprini, Sabrina, Friedrichsen, Sonke, Harper, Claire V, McNeilly, Judith R, Adamson, Antony D, Spiller, David G, Kotelevtseva, Nina, Brooker, Gillian, Brownstein, David G, McNeilly, Alan S, White, Michael R. H, Davis, Julian R. E, Mullins, John J

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A missense mutation in the murine Opa3 gene models human Costeff syndrome von Davies, Vanessa J., Powell, Kate A., White, Kathryn E., Yip, Wanfen, Hogan, Vanessa, Hollins, Andrew J., Davies, Jennifer R., Piechota, Malgorzata, Brownstein, David G., Moat, Stuart J., Nichols, Philip P., Wride, Michael A., Boulton, Michael E., Votruba, Marcela

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A neurological phenotype in mice with DNA repair gene Ercc1 deficiency von Lawrence, Nicola J., Sacco, Joseph J., Brownstein, David G., Gillingwater, Thomas H., Melton, David W.

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The K-Ras 4A isoform promotes apoptosis but does not affect either lifespan or spontaneous tumor incidence in aging mice von Plowman, Sarah J., Arends, Mark J., Brownstein, David G., Luo, Feijun, Devenney, Paul S., Rose, Lorraine, Ritchie, Ann-Marie, Berry, Rachel L., Harrison, David J., Hooper, Martin L., Patek, Charles E.

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Murine Gammaherpesvirus-68 Infection Causes Multi-Organ Fibrosis and Alters Leukocyte Trafficking in Interferon-γ Receptor Knockout Mice von Ebrahimi, Bahram, Dutia, Bernadette M., Brownstein, David G., Nash, Anthony A.

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Topical thymidine dinucleotide application protects against UVB-induced skin cancer in mice with DNA repair gene ( Ercc1)-deficient skin von Lawrence, Nicola J., Song, Liang, Doig, Jennifer, Ritchie, Ann-Marie, Brownstein, David G., Melton, David W.

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