MICE Models: Superior to the HERG Model in Predicting Torsade de Pointes von Kramer, James, Obejero-Paz, Carlos A., Myatt, Glenn, Kuryshev, Yuri A., Bruening-Wright, Andrew, Verducci, Joseph S., Brown, Arthur M.

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A history of the role of the hERG channel in cardiac risk assessment von Rampe, David, Brown, Arthur M.

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Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes von Doherty, Kimberly R., Wappel, Robert L., Talbert, Dominique R., Trusk, Patricia B., Moran, Diarmuid M., Kramer, James W., Brown, Arthur M., Shell, Scott A., Bacus, Sarah

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The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes von Peng, Shengde, Lacerda, Antonio E., Kirsch, Glenn E., Brown, Arthur M., Bruening-Wright, Andrew

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Role of the Cytosolic Chaperones Hsp70 and Hsp90 in Maturation of the Cardiac Potassium Channel hERG von Ficker, Eckhard, Dennis, Adrienne T, Wang, Lu, Brown, Arthur M

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Mechanisms of Arsenic-Induced Prolongation of Cardiac Repolarization von Ficker, Eckhard, Kuryshev, Yuri A, Dennis, Adrienne T, Obejero-Paz, Carlos, Wang, Lu, Hawryluk, Peter, Wible, Barbara A, Brown, Arthur M

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Quantitative Profiling of the Effects of Vanoxerine on Human Cardiac Ion Channels and its Application to Cardiac Risk von Obejero-Paz, Carlos A., Bruening-Wright, Andrew, Kramer, James, Hawryluk, Peter, Tatalovic, Milos, Dittrich, Howard C., Brown, Arthur M.

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COR-ART: A multicenter, randomized, double-blind, placebo-controlled dose-ranging study to evaluate single oral doses of vanoxerine for conversion of recent-onset atrial fibrillati... von Dittrich, Howard C., MD, Feld, Gregory K., MD, FHRS, Bahnson, Tristram D., MD, FHRS, Camm, A. John, MD, FHRS, Golitsyn, Sergey, MD, Katz, Amos, MD, Koontz, Jason I., MD, PhD, Kowey, Peter R., MD, FHRS, Waldo, Albert L., MD, PhD, FHRS (Hon), Brown, Arthur M., MD, PhD

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Evaluating state dependence and subtype selectivity of calcium channel modulators in automated electrophysiology assays von Kuryshev, Yuri A, Brown, Arthur M, Duzic, Emir, Kirsch, Glenn E

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Variability in the measurement of hERG potassium channel inhibition: Effects of temperature and stimulus pattern von Kirsch, Glenn E., Trepakova, Elena S., Brimecombe, Jessica C., Sidach, Serguei S., Erickson, Hope D., Kochan, Mary C., Shyjka, Lisa M., Lacerda, Antonio E., Brown, Arthur M.

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The Binding Site for Channel Blockers That Rescue Misprocessed Human Long QT Syndrome Type 2 ether-a-gogo-related Gene (HERG) Mutations von Ficker, Eckhard, Zhao, Shuxia, Obejero-Paz, Carlos A., Brown, Arthur M.

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High throughput functional screening of an ion channel library for drug safety and efficacy von Brown, Arthur M

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Vanoxerine: Cellular Mechanism of a New Antiarrhythmic von LACERDA, ANTONIO E., KURYSHEV, YURI A., YAN, GAN-XIN, WALDO, ALBERT L., BROWN, ARTHUR M.

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Molecular Determinants of Dofetilide Block of HERG K+ Channels von Ficker, Eckhard, Jarolimek, Wolfgang, Kiehn, Johann, Baumann, Arnd, Brown, Arthur M

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A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG von Rampe, David, Roy, Mary-Louise, Dennis, Adrienne, Brown, Arthur M

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Spermine and Spermidine as Gating Molecules for Inward Rectifier $K^+$ Channels von Ficker, Eckhard, Taglialatela, Maurizio, Wible, Barbara A., Henley, Charles M., Brown, Arthur M.

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HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine von ROY, M.-L, DUMAINE, R, BROWN, A. M

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Vanoxerine, a New Drug for Terminating Atrial Fibrillation and Flutter von MATSUMOTO, NAOMICHI, KHRESTIAN, CELEEN M., RYU, KYUNGMOO, LACERDA, ANTONIO E., BROWN, ARTHUR M., WALDO, ALBERT L.

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Multiple mechanisms of Na+ channel-linked long-QT syndrome von DUMAINE, R, QING WANG, KEATING, M. T, HARTMANN, H. A, SCHWARTZ, P. J, BROWN, A. M, KIRSCH, G. E

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Test article concentrations in the hERG assay: Losses through the perfusion, solubility and stability von Brimecombe, Jessica C., Kirsch, Glenn E., Brown, Arthur M.

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