The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL von Humbert, Magali, Federzoni, Elena A., Britschgi, Adrian, Schläfli, Anna M., Valk, Peter J. M., Kaufmann, Thomas, Haferlach, Torsten, Behre, Gerhard, Simon, Hans‐Uwe, Torbett, Bruce E., Fey, Martin F., Tschan, Mario P.

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Male dominance linked to size and age, but not to 'good genes' in brown trout (Salmo trutta) von Jacob, Alain, Nusslé, Sébastien, Britschgi, Adrian, Evanno, Guillaume, Müller, Rudolf, Wedekind, Claus

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PIK3CA(H1047R) induces multipotency and multi-lineage mammary tumours von Koren, Shany, Reavie, Linsey, Couto, Joana Pinto, De Silva, Duvini, Stadler, Michael B, Roloff, Tim, Britschgi, Adrian, Eichlisberger, Tobias, Kohler, Hubertus, Aina, Olulanu, Cardiff, Robert D, Bentires-Alj, Mohamed

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JAK2/STAT5 Inhibition Circumvents Resistance to PI3K/mTOR Blockade: A Rationale for Cotargeting These Pathways in Metastatic Breast Cancer von Britschgi, Adrian, Andraos, Rita, Brinkhaus, Heike, Klebba, Ina, Romanet, Vincent, Müller, Urs, Murakami, Masato, Radimerski, Thomas, Bentires-Alj, Mohamed

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Cellular Resistance Mechanisms to Targeted Protein Degradation Converge Toward Impairment of the Engaged Ubiquitin Transfer Pathway von Ottis, Philipp, Palladino, Chiara, Thienger, Phillip, Britschgi, Adrian, Heichinger, Christian, Berrera, Marco, Julien-Laferriere, Alice, Roudnicky, Filip, Kam-Thong, Tony, Bischoff, James R, Martoglio, Bruno, Pettazzoni, Piergiorgio

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The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα von Britschgi, Adrian, Duss, Stephan, Kim, Sungeun, Couto, Joana Pinto, Brinkhaus, Heike, Koren, Shany, De Silva, Duvini, Mertz, Kirsten D., Kaup, Daniela, Varga, Zsuzsanna, Voshol, Hans, Vissieres, Alexandra, Leroy, Cedric, Roloff, Tim, Stadler, Michael B., Scheel, Christina H., Miraglia, Loren J., Orth, Anthony P., Bonamy, Ghislain M. C., Reddy, Venkateshwar A., Bentires-Alj, Mohamed

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A high-throughput drug screen reveals means to differentiate triple-negative breast cancer von Vulin, Milica, Jehanno, Charly, Sethi, Atul, Correia, Ana Luísa, Obradović, Milan M. S., Couto, Joana Pinto, Coissieux, Marie-May, Diepenbruck, Maren, Preca, Bogdan-Tiberius, Volkmann, Katrin, der Maur, Priska Auf, Schmidt, Alexander, Münst, Simone, Sauteur, Loïc, Kloc, Michal, Palafox, Marta, Britschgi, Adrian, Unterreiner, Vincent, Galuba, Olaf, Claerr, Isabelle, Lopez-Romero, Sandra, Galli, Giorgio G., Baeschlin, Daniel, Okamoto, Ryoko, Soysal, Savas D., Mechera, Robert, Weber, Walter P., Radimerski, Thomas, Bentires-Alj, Mohamed

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Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy von Yousefi, Shida, Simon, Hans-Uwe, Tschan, Mario P., Ernst, Marion, Federzoni, Elena A., Batliner, Jasmin, Shan-Krauer, Deborah, Humbert, Magali, Schläfli, Anna M., Britschgi, Adrian, Jin, Jing, Torbett, Bruce E.

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Induction of autophagy is a key component of all- trans -retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation von Orfali, Nina, O'Donovan, Tracey R, Nyhan, Michelle J, Britschgi, Adrian, Tschan, Mario P, Cahill, Mary R, Mongan, Nigel P, Gudas, Lorraine J, McKenna, Sharon L

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Hippo inactivation feeds tumor-initiating cells von Duss, Stephan, Britschgi, Adrian, Bentires-Alj, Mohamed

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Epigallocatechin‐3‐gallate induces cell death in acute myeloid leukaemia cells and supports all‐trans retinoic acid‐induced neutrophil differentiation via death‐associated protein... von Britschgi, Adrian, Simon, Hans‐Uwe, Tobler, Andreas, Fey, Martin F., Tschan, Mario P.

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Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation von Geering, Barbara, Zokouri, Zina, Hürlemann, Samuel, Gerrits, Bertran, Ausländer, David, Britschgi, Adrian, Tschan, Mario P., Simon, Hans-Uwe, Fussenegger, Martin

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Mesenchymal precursor cells maintain the differentiation and proliferation potentials of breast epithelial cells von Duss, Stephan, Brinkhaus, Heike, Britschgi, Adrian, Cabuy, Erik, Frey, Daniel M, Schaefer, Dirk J, Bentires-Alj, Mohamed

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Abstract 3305: Hippo kinases LATS1/2 control human breast cell fate von Britschgi, Adrian, Duss, Stephan, Kim, Sungeun, Brinkhaus, Heike, Pinto Couto, Joana, De Silva, Duvini, Miraglia, Loren, Stadler, Michael B., Orth, Anthony P., Bonamy, Ghislain M.C., Reddy, Venkateshwar A., Bentires-Alj, Mohamed

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The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα von Britschgi, Adrian, Duss, Stephan, Kim, Sungeun, Couto, Joana Pinto, Brinkhaus, Heike, Koren, Shany, De Silva, Duvini, Mertz, Kirsten D, Kaup, Daniela, Varga, Zsuzsanna, Voshol, Hans, Vissieres, Alexandra, Leroy, Cedric, Roloff, Tim, Stadler, Michael B, Scheel, Christina H, Miraglia, Loren J, Orth, Anthony P, Bonamy, Ghislain M C, Reddy, Venkateshwar A, Bentires-Alj, Mohamed

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induces multipotency and multi-lineage mammary tumours von Koren, Shany, Reavie, Linsey, Couto, Joana Pinto, De Silva, Duvini, Stadler, Michael B, Roloff, Tim, Britschgi, Adrian, Eichlisberger, Tobias, Kohler, Hubertus, Aina, Olulanu, Cardiff, Robert D, Bentires-Alj, Mohamed

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Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacological modulation von Orfali, Nina, O’Donovan, Tracey R., Nyhan, Michelle J., Britschgi, Adrian, Tschan, Mario P., Cahill, Mary R., Mongan, Nigel P., Gudas, Lorraine J., McKenna, Sharon L.

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Abstract LB-205: The calcium activated chloride channel ANO1 promotes breast cancer progression by activating EGFR- and CAMK-signaling von Britschgi, Adrian, Bill, Anke, Brinkhaus, Heike, Rothwell, Christopher, Clay, Ieuan, Duss, Stephan, Rebhan, Michael, Raman, Pichai, Guy, Chantale, Wetzel, Kristie, George, Elizabeth, Popa, M. Oana, Lilley, Sarah, Choudhury, Hedaythul, Gosling, Martin, Wang, Louis, Fitzgerald, Stephanie, Borawski, Jason, Baffoe, Jonathan, Labow, Mark, Gaither, L. Alex, Bentires-Alj, Mohamed

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Green Tea Catechin Epigallocatechin-3-Gallate (EGCG) Induces Cell Death in Acute Myeloid Leukemic Cells Via DAPK2 and Potentiates ATRA-Induced Neutrophil Differentiation von Britschgi, Adrian, Simon, Hans-Uwe, Tobler, Andreas, Fey, Martin F., Tschan, Mario P.

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The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1 von Jenal, Mathias, Trinh, Emmanuelle, Britschgi, Christian, Britschgi, Adrian, Roh, Vincent, Vorburger, Stephan A, Tobler, Andreas, Leprince, Dominique, Fey, Martin F, Helin, Kristian, Tschan, Mario P

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