Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4 von Lyssiotis, Costas A, Foreman, Ruth K, Staerk, Judith, Garcia, Michael, Mathur, Divya, Markoulaki, Styliani, Hanna, Jacob, Lairson, Luke L, Charette, Bradley D, Bouchez, Laure C, Bollong, Michael, Kunick, Conrad, Brinker, Achim, Cho, Charles Y, Schultz, Peter G, Jaenisch, Rudolf

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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen von Plouffe, David, Brinker, Achim, McNamara, Case, Henson, Kerstin, Kato, Nobutaka, Kuhen, Kelli, Nagle, Advait, Adrián, Francisco, Matzen, Jason T, Anderson, Paul, Nam, Tae-gyu, Gray, Nathanael S, Chatterjee, Arnab, Janes, Jeff, Yan, S. Frank, Trager, Richard, Caldwell, Jeremy S, Schultz, Peter G, Zhou, Yingyao, Winzeler, Elizabeth A

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Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity von Ramadoss, Nitya S., Alumasa, John N., Cheng, Lin, Wang, Yu, Li, Sharon, Chambers, Benjamin S., Chang, Hoon, Chatterjee, Arnab K., Brinker, Achim, Engels, Ingo H., Keiler, Kenneth C.

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In vivo Incorporation of Unnatural Amino Acids to Probe Structure, Dynamics, and Ligand Binding in a Large Protein by Nuclear Magnetic Resonance Spectroscopy von Cellitti, Susan E, Jones, David H, Lagpacan, Leanna, Hao, Xueshi, Zhang, Qiong, Hu, Huiyong, Brittain, Scott M, Brinker, Achim, Caldwell, Jeremy, Bursulaya, Badry, Spraggon, Glen, Brock, Ansgar, Ryu, Youngha, Uno, Tetsuo, Schultz, Peter G, Geierstanger, Bernhard H

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Synthetic Small Molecules That Control Stem Cell Fate von Ding, Sheng, Tom Y. H. Wu, Brinker, Achim, Peters, Eric C., Hur, Wooyoung, Gray, Nathanael S., Schultz, Peter G.

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Dual Function of Protein Confinement in Chaperonin-Assisted Protein Folding von Brinker, Achim, Pfeifer, Guenther, Kerner, Michael J., Naylor, Dean J., Hartl, F.Ulrich, Hayer-Hartl, Manajit

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Profiling of Tyrosine Phosphorylation Pathways in Human Cells Using Mass Spectrometry von Salomon, Arthur R., Ficarro, Scott B., Brill, Laurence M., Brinker, Achim, Phung, Qui T., Ericson, Christer, Sauer, Karsten, Brock, Ansgar, Horn, David M., Schultz, Peter G., Peters, Eric C.

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Role of the Myosin Assembly Protein UNC-45 as a Molecular Chaperone for Myosin von Barral, José M., Hutagalung, Alex H., Brinker, Achim, Hartl, F. Ulrich, Epstein, Henry F.

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Pan-Src Family Kinase Inhibitors Replace Sox2 during the Direct Reprogramming of Somatic Cells von Staerk, Judith, Lyssiotis, Costas A., Medeiro, Lea A., Bollong, Michael, Foreman, Ruth K., Zhu, Shoutian, Garcia, Michael, Gao, Qing, Bouchez, Laure C., Lairson, Luke L., Charette, Bradley D., Supekova, Lubica, Janes, Jeffrey, Brinker, Achim, Cho, Charles Y., Jaenisch, Rudolf, Schultz, Peter G.

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Evaluating Sandwich Immunoassays in Microarray Format in Terms of the Ambient Analyte Regime von Saviranta, Petri, Okon, Ryan, Brinker, Achim, Warashina, Masaki, Eppinger, Joerg, Geierstanger, Bernhard H

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Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening von O'Leary, Debra A, Sharif, Orzala, Anderson, Paul, Tu, Buu, Welch, Genevieve, Zhou, Yingyao, Caldwell, Jeremy S, Engels, Ingo H, Brinker, Achim

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Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine von Scheufler, C, Brinker, A, Bourenkov, G, Pegoraro, S, Moroder, L, Bartunik, H, Hartl, F U, Moarefi, I

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A biochemical screen for GroEL/GroES inhibitors von Johnson, Steven M., Sharif, Orzala, Mak, Puiying Annie, Wang, Hsiao-Ting, Engels, Ingo H., Brinker, Achim, Schultz, Peter G., Horwich, Arthur L., Chapman, Eli

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The Rise of the PTAB and Its Implications for Biopharma Patents von McNicholas, Janet M., Johnson, Matthew, Brinker, Achim

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Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds von Crowther, Gregory J., Napuli, Alberto J., Gilligan, James H., Gagaring, Kerstin, Borboa, Rachel, Francek, Carolyn, Chen, Zhong, Dagostino, Eleanor F., Stockmyer, Justin B., Wang, Yu, Rodenbough, Philip P., Castaneda, Lisa J., Leibly, David J., Bhandari, Janhavi, Gelb, Michael H., Brinker, Achim, Engels, Ingo H., Taylor, Jennifer, Chatterjee, Arnab K., Fantauzzi, Pascal, Glynne, Richard J., Van Voorhis, Wesley C., Kuhen, Kelli L.

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Immunoassay and antibody microarray analysis of the HUPO Plasma Proteome Project reference specimens: Systematic variation between sample types and calibration of mass spectrometry... von Haab, Brian B., Geierstanger, Bernhard H., Michailidis, George, Vitzthum, Frank, Forrester, Sara, Okon, Ryan, Saviranta, Petri, Brinker, Achim, Sorette, Martin, Perlee, Lorah, Suresh, Shubha, Drwal, Garry, Adkins, Joshua N., Omenn, Gilbert S.

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Structural Plasticity and Noncovalent Substrate Binding in the GroEL Apical Domain von Ashcroft, Alison E., Brinker, Achim, Coyle, Joseph E., Weber, Frank, Kaiser, Markus, Moroder, Luis, Parsons, Mark R., Jager, Joachim, Hartl, Ulrich F., Hayer-Hartl, Manajit, Radford, Sheena E.

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Ligand Discrimination by TPR Domains von Brinker, Achim, Scheufler, Clemens, von der Mülbe, Florian, Fleckenstein, Burkhard, Herrmann, Christian, Jung, Günther, Moarefi, Ismail, Hartl, F. Ulrich

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Crystal structures of human HSP90α-complexed with dihydroxyphenylpyrazoles von Kreusch, Andreas, Han, Shulin, Brinker, Achim, Zhou, Vicki, Choi, Ha-soon, He, Yun, Lesley, Scott A., Caldwell, Jeremy, Gu, Xiang-ju

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Structure of TPR Domain–Peptide Complexes von Scheufler, Clemens, Brinker, Achim, Bourenkov, Gleb, Pegoraro, Stefano, Moroder, Luis, Bartunik, Hans, Hartl, F.Ulrich, Moarefi, Ismail

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