Optimization of scarless human stem cell genome editing von Yang, Luhan, Guell, Marc, Byrne, Susan, Yang, Joyce L, De Los Angeles, Alejandro, Mali, Prashant, Aach, John, Kim-Kiselak, Caroline, Briggs, Adrian W, Rios, Xavier, Huang, Po-Yi, Daley, George, Church, George

Volltext

Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA von Briggs, Adrian W, Stenzel, Udo, Meyer, Matthias, Krause, Johannes, Kircher, Martin, Pääbo, Svante

Volltext

Genetic history of an archaic hominin group from Denisova Cave in Siberia von Reich, David, Viola, Bence, Pääbo, Svante, Green, Richard E, Kircher, Martin, Krause, Johannes, Patterson, Nick, Durand, Eric Y, Briggs, Adrian W, Stenzel, Udo, Johnson, Philip L. F, Maricic, Tomislav, Good, Jeffrey M, Marques-Bonet, Tomas, Alkan, Can, Fu, Qiaomei, Mallick, Swapan, Li, Heng, Meyer, Matthias, Eichler, Evan E, Stoneking, Mark, Richards, Michael, Talamo, Sahra, Shunkov, Michael V, Derevianko, Anatoli P, Hublin, Jean-Jacques, Kelso, Janet, Slatkin, Montgomery

Volltext

A Complete mtDNA Genome of an Early Modern Human from Kostenki, Russia von Krause, Johannes, Briggs, Adrian W., Kircher, Martin, Maricic, Tomislav, Zwyns, Nicolas, Derevianko, Anatoli, Pääbo, Svante

Volltext

Hierarchical Clustering Can Identify B Cell Clones with High Confidence in Ig Repertoire Sequencing Data von Gupta, Namita T, Adams, Kristofor D, Briggs, Adrian W, Timberlake, Sonia C, Vigneault, Francois, Kleinstein, Steven H

Volltext

Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers von Briggs, Adrian W, Rios, Xavier, Chari, Raj, Yang, Luhan, Zhang, Feng, Mali, Prashant, Church, George M

Volltext

Mitochondrial genomes reveal an explosive radiation of extinct and extant bears near the Miocene-Pliocene boundary von Krause, Johannes, Unger, Tina, Noçon, Aline, Malaspinas, Anna-Sapfo, Kolokotronis, Sergios-Orestis, Stiller, Mathias, Soibelzon, Leopoldo, Spriggs, Helen, Dear, Paul H, Briggs, Adrian W, Bray, Sarah C E, O'Brien, Stephen J, Rabeder, Gernot, Matheus, Paul, Cooper, Alan, Slatkin, Montgomery, Pääbo, Svante, Hofreiter, Michael

Volltext

Engineering and optimising deaminase fusions for genome editing von Yang, Luhan, Briggs, Adrian W., Chew, Wei Leong, Mali, Prashant, Guell, Marc, Aach, John, Goodman, Daniel Bryan, Cox, David, Kan, Yinan, Lesha, Emal, Soundararajan, Venkataramanan, Zhang, Feng, Church, George

Volltext

Patterns of Damage in Genomic DNA Sequences from a Neandertal von Briggs, Adrian W., Stenzel, Udo, Johnson, Philip L. F., Green, Richard E., Kelso, Janet, Prüfer, Kay, Meyer, Matthias, Krause, Johannes, Ronan, Michael T., Lachmann, Michael, Pääbo, Svante

Volltext

Single T Cell Sequencing Demonstrates the Functional Role of αβ TCR Pairing in Cell Lineage and Antigen Specificity von Carter, Jason A, Preall, Jonathan B, Grigaityte, Kristina, Goldfless, Stephen J, Jeffery, Eric, Briggs, Adrian W, Vigneault, Francois, Atwal, Gurinder S

Volltext

Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes von Briggs, Adrian W, Good, Jeffrey M, Green, Richard E, Krause, Johannes, Maricic, Tomislav, Stenzel, Udo, Lalueza-Fox, Carles, Rudan, Pavao, Brajković, Dejana, Kućan, Željko, Gušić, Ivan, Schmitz, Ralf, Doronichev, Vladimir B, Golovanova, Liubov V, de la Rasilla, Marco, Fortea, Javier, Rosas, Antonio, Pääbo, Svante

Volltext

Analysis of one million base pairs of Neanderthal DNA von Ronan, Michael T, Egholm, Michael, Paunovic, Maja, Pääbo, Svante, Green, Richard E, Ptak, Susan E, Rothberg, Jonathan M, Briggs, Adrian W, Simons, Jan F, Krause, Johannes, Du, Lei

Volltext

Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers von Spencer, Sarah J, Tamminen, Manu V, Preheim, Sarah P, Guo, Mira T, Briggs, Adrian W, Brito, Ilana L, A Weitz, David, Pitkänen, Leena K, Vigneault, Francois, Virta, Marko PJuhani, Alm, Eric J

Volltext

A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data von Cui, Ang, Di Niro, Roberto, Vander Heiden, Jason A, Briggs, Adrian W, Adams, Kris, Gilbert, Tamara, O'Connor, Kevin C, Vigneault, Francois, Shlomchik, Mark J, Kleinstein, Steven H

Volltext

The Neandertal genome and ancient DNA authenticity von Green, Richard E, Briggs, Adrian W, Krause, Johannes, Prüfer, Kay, Burbano, Hernán A, Siebauer, Michael, Lachmann, Michael, Pääbo, Svante

Volltext

Targeted Investigation of the Neandertal Genome by Array-Based Sequence Capture von Burbano, Hernán A, Hodges, Emily, Green, Richard E, Briggs, Adrian W, Krause, Johannes, Meyer, Matthias, Good, Jeffrey M, Maricic, Tomislav, Johnson, Philip L.F, Xuan, Zhenyu, Rooks, Michelle, Bhattacharjee, Arindam, Brizuela, Leonardo, Albert, Frank W, de la Rasilla, Marco, Fortea, Javier, Rosas, Antonio, Lachmann, Michael, Hannon, Gregory J, Pääbo, Svante

Volltext

A High-Coverage Genome Sequence from an Archaic Denisovan Individual von Meyer, Matthias, Kircher, Martin, Gansauge, Marie-Theres, Li, Heng, Racimo, Fernando, Mallick, Swapan, Schraiber, Joshua G., Jay, Flora, Prüfer, Kay, de Filippo, Cesare, Sudmant, Peter H., Alkan, Can, Fu, Qiaomei, Do, Ron, Rohland, Nadin, Tandon, Arti, Siebauer, Michael, Green, Richard E., Bryc, Katarzyna, Briggs, Adrian W., Stenzel, Udo, Dabney, Jesse, Shendure, Jay, Kitzman, Jacob, Hammer, Michael F., Shunkov, Michael V., Derevianko, Anatoli P., Patterson, Nick, Andrés, Aida M., Eichler, Evan E., Slatkin, Montgomery, Reich, David, Kelso, Janet, Pääbo, Svante

Volltext

Road blocks on paleogenomes--polymerase extension profiling reveals the frequency of blocking lesions in ancient DNA von Heyn, Patricia, Stenzel, Udo, Briggs, Adrian W, Kircher, Martin, Hofreiter, Michael, Meyer, Matthias

Volltext

Stable gene targeting in human cells using single-strand oligonucleotides with modified bases von Rios, Xavier, Briggs, Adrian W, Christodoulou, Danos, Gorham, Josh M, Seidman, Jonathan G, Church, George M

Volltext

Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing von Tsioris, Konstantinos, Gupta, Namita T, Ogunniyi, Adebola O, Zimnisky, Ross M, Qian, Feng, Yao, Yi, Wang, Xiaomei, Stern, Joel N H, Chari, Raj, Briggs, Adrian W, Clouser, Christopher R, Vigneault, Francois, Church, George M, Garcia, Melissa N, Murray, Kristy O, Montgomery, Ruth R, Kleinstein, Steven H, Love, J Christopher

Volltext