Discrete adjunct attachment feature for surgical stapler von BREHM TIMOTHY N, ARONHALT TAYLOR W, BRIDGES ANDREW JAMES, SEOW CHANG Q, DAPPEL, DANIEL, M, BOUDREAUX CHAD P, HUANG ZUBIN, MESNIER PAUL R, HUNTER MORGAN R

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Circular surgical stapler for forming pattern of non-tangential staples von BAKOS GREGORY J, FEDDES JOHN E, MCGEE, ROBERT, W, BRIDGES ANDREW JAMES, BRADY JOHN E, PATEL ROHEET, VOEGELE AARON C, ROCKMAN, MICHAEL, T, BRUNS, JENS, S.A.JENKINS, DOWNING LINDA S, JONES, STEPHEN, L

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Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia von Hering, Bernhard J, Clarke, William R, Bridges, Nancy D, Eggerman, Thomas L, Alejandro, Rodolfo, Bellin, Melena D, Chaloner, Kathryn, Czarniecki, Christine W, Goldstein, Julia S, Hunsicker, Lawrence G, Kaufman, Dixon B, Korsgren, Olle, Larsen, Christian P, Luo, Xunrong, Markmann, James F, Naji, Ali, Oberholzer, Jose, Posselt, Andrew M, Rickels, Michael R, Ricordi, Camillo, Robien, Mark A, Senior, Peter A, Shapiro, A M James, Stock, Peter G, Turgeon, Nicole A

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Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry von Zhang, Fan, Wei, Kevin, Slowikowski, Kamil, Fonseka, Chamith Y., Rao, Deepak A., Kelly, Stephen, Goodman, Susan M., Tabechian, Darren, Hughes, Laura B., Salomon-Escoto, Karen, Watts, Gerald F. M., Jonsson, A. Helena, Rangel-Moreno, Javier, Meednu, Nida, Rozo, Cristina, Apruzzese, William, Eisenhaure, Thomas M., Lieb, David J., Boyle, David L., Mandelin, Arthur M., Boyce, Brendan F., DiCarlo, Edward, Gravallese, Ellen M., Gregersen, Peter K., Moreland, Larry, Firestein, Gary S., Hacohen, Nir, Nusbaum, Chad, Lederer, James A., Perlman, Harris, Pitzalis, Costantino, Filer, Andrew, Holers, V. Michael, Bykerk, Vivian P., Donlin, Laura T., Anolik, Jennifer H., Brenner, Michael B., Raychaudhuri, Soumya

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Notch signalling drives synovial fibroblast identity and arthritis pathology von Wei, Kevin, Korsunsky, Ilya, Marshall, Jennifer L., Gao, Anqi, Watts, Gerald F. M., Major, Triin, Croft, Adam P., Watts, Jordan, Blazar, Philip E., Lange, Jeffrey K., Thornhill, Thomas S., Filer, Andrew, Raza, Karim, Donlin, Laura T., Siebel, Christian W., Buckley, Christopher D., Raychaudhuri, Soumya, Brenner, Michael B.

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Structural basis for a complex I mutation that blocks pathological ROS production von Yin, Zhan, Burger, Nils, Kula-Alwar, Duvaraka, Aksentijević, Dunja, Bridges, Hannah R., Prag, Hiran A., Grba, Daniel N., Viscomi, Carlo, James, Andrew M., Mottahedin, Amin, Krieg, Thomas, Murphy, Michael P., Hirst, Judy

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Phase 3 trial of human islet‐after‐kidney transplantation in type 1 diabetes von Markmann, James F., Rickels, Michael R., Eggerman, Thomas L., Bridges, Nancy D., Lafontant, David E., Qidwai, Julie, Foster, Eric, Clarke, William R., Kamoun, Malek, Alejandro, Rodolfo, Bellin, Melena D., Chaloner, Kathryn, Czarniecki, Christine W., Goldstein, Julia S., Hering, Bernhard J., Hunsicker, Lawrence G., Kaufman, Dixon B., Korsgren, Olle, Larsen, Christian P., Luo, Xunrong, Naji, Ali, Oberholzer, José, Posselt, Andrew M., Ricordi, Camillo, Senior, Peter A., Shapiro, A. M. James, Stock, Peter G., Turgeon, Nicole A.

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National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities von Ricordi, Camillo, Goldstein, Julia S, Balamurugan, A N, Szot, Gregory L, Kin, Tatsuya, Liu, Chengyang, Czarniecki, Christine W, Barbaro, Barbara, Bridges, Nancy D, Cano, Jose, Clarke, William R, Eggerman, Thomas L, Hunsicker, Lawrence G, Kaufman, Dixon B, Khan, Aisha, Lafontant, David-Erick, Linetsky, Elina, Luo, Xunrong, Markmann, James F, Naji, Ali, Korsgren, Olle, Oberholzer, Jose, Turgeon, Nicole A, Brandhorst, Daniel, Chen, Xiaojuan, Friberg, Andrew S, Lei, Ji, Wang, Ling-Jia, Wilhelm, Joshua J, Willits, Jamie, Zhang, Xiaomin, Hering, Bernhard J, Posselt, Andrew M, Stock, Peter G, Shapiro, A M James, Chen, Xiaojuan

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Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation von Douketis, James D, Spyropoulos, Alex C, Kaatz, Scott, Becker, Richard C, Caprini, Joseph A, Dunn, Andrew S, Garcia, David A, Jacobson, Alan, Jaffer, Amir K, Kong, David F, Schulman, Sam, Turpie, Alexander G.G, Hasselblad, Vic, Ortel, Thomas L

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Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes von Zhang, Fan, Jonsson, Anna Helena, Nathan, Aparna, Millard, Nghia, Curtis, Michelle, Xiao, Qian, Gutierrez-Arcelus, Maria, Apruzzese, William, Watts, Gerald F. M., Weisenfeld, Dana, Nayar, Saba, Rangel-Moreno, Javier, Meednu, Nida, Marks, Kathryne E., Mantel, Ian, Kang, Joyce B., Rumker, Laurie, Mears, Joseph, Slowikowski, Kamil, Weinand, Kathryn, Orange, Dana E., Geraldino-Pardilla, Laura, Deane, Kevin D., Tabechian, Darren, Ceponis, Arnoldas, Firestein, Gary S., Maybury, Mark, Sahbudin, Ilfita, Ben-Artzi, Ami, Mandelin, Arthur M., Nerviani, Alessandra, Lewis, Myles J., Rivellese, Felice, Pitzalis, Costantino, Hughes, Laura B., Horowitz, Diane, DiCarlo, Edward, Gravallese, Ellen M., Boyce, Brendan F., Moreland, Larry W., Goodman, Susan M., Perlman, Harris, Holers, V. Michael, Liao, Katherine P., Filer, Andrew, Bykerk, Vivian P., Wei, Kevin, Rao, Deepak A., Donlin, Laura T., Anolik, Jennifer H., Brenner, Michael B., Raychaudhuri, Soumya

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Evidential requirements for the regulatory hazard and risk assessment of respiratory sensitisers: methyl methacrylate as an example von Meek, Bette, Bridges, James W., Fasey, Andrew, Sauer, Ursula G.

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Therapies for Active Rheumatoid Arthritis after Methotrexate Failure von O'Dell, James R, Mikuls, Ted R, Taylor, Thomas H, Ahluwalia, Vandana, Brophy, Mary, Warren, Stuart R, Lew, Robert A, Cannella, Amy C, Kunkel, Gary, Phibbs, Ciaran S, Anis, Aslam H, Leatherman, Sarah, Keystone, Edward

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Improved Health-Related Quality of Life in a Phase 3 Islet Transplantation Trial in Type 1 Diabetes Complicated by Severe Hypoglycemia von Foster, Eric D, Bridges, Nancy D, Feurer, Irene D, Eggerman, Thomas L, Hunsicker, Lawrence G, Alejandro, Rodolfo

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Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue von Bell, Richard D., Brendel, Matthew, Konnaris, Maxwell A., Xiang, Justin, Otero, Miguel, Fontana, Mark A., Bai, Zilong, Krenitsky, Daria M., Meednu, Nida, Rangel-Moreno, Javier, Scheel-Toellner, Dagmar, Carr, Hayley, Nayar, Saba, McMurray, Jack, DiCarlo, Edward, Anolik, Jennifer H., Donlin, Laura T., Orange, Dana E., Kenney, H. Mark, Schwarz, Edward M., Filer, Andrew, Ivashkiv, Lionel B., Wang, Fei

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Three-Year, Randomized, Sham-Controlled Trial of Dexamethasone Intravitreal Implant in Patients with Diabetic Macular Edema von Boyer, David S., MD, Yoon, Young Hee, MD, PhD, Belfort, Rubens, MD, PhD, Bandello, Francesco, MD, Maturi, Raj K., MD, Augustin, Albert J., MD, Li, Xiao-Yan, MD, Cui, Harry, MS, Hashad, Yehia, MD, Whitcup, Scott M., MD

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Mineralogy of a Mudstone at Yellowknife Bay, Gale Crater, Mars von Vaniman, D. T., Bish, D. L., Ming, D. W., Bristow, T. F., Morris, R. V., Blake, D. F., Chipera, S. J., Morrison, S. M., Treiman, A. H., Rampe, E. B., Rice, M., Achilles, C. N., Grotzinger, J. P., McLennan, S. M., Williams, J., Bell, J. F., Newsom, H. E., Downs, R. T., Maurice, S., Sarrazin, P., Yen, A. S., Morookian, J. M., Farmer, J. D., Stack, K., Milliken, R. E., Ehlmann, B. L., Sumner, D. Y., Berger, G., Crisp, J. A., Hurowitz, J. A., Anderson, R., Des Marais, D. J., Stolper, E. M., Edgett, K. S., Gupta, S., Spanovich, N.

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Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK von Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Hill, Helen, Lazarus, Rajeka, Lawrie, Alison M, McGregor, Alastair, Villafana, Tonya L, Gilbert, Sarah C, Aban, Marites, Aboagye, Jeremy, Adam, Matthew, Adams, Kirsty, Alves, Mariana P.S., Barnes, Eleanor, Berrie, Eleanor, Bewley, Kevin R., Bletchly, Heather, Borthwick, Nicola, Brown, Phillip, Buttigieg, Karen R., Cashen, Paul, Castro, Lucia Carratala, Chadwick, Jim, Chapman, David, Charlton, Sue, Clark, Matthew, Clutterbuck, Elizabeth A., Cooper, Cushla, Cooper, Rachel, Darroch, Paula, Dearlove, David, Drake-Brockman, Rachael, van Eck, Samual, Farrar, Madi, Fraiman, Pedro H.A., Gracie, Lara, Grossi, Leonardo, Hanrath, Aidan T., Harris, Tara, Hassan, Shadin, Hay, Jodie, Head, Ian, Hodges, Gina, Horne, Elizea, Hou, Mimi M., Humphries, Holly E., Hyder-Wright, Angela, Jeffers, Helen, Karampatsas, Konstantinos, Keen, Jade, Khan, Liaquat, King, Thomas B., Klenerman, Paul, Lees, Emily A., Li, Yuanyuan, Loew, Lisa, Marques, Gabriela N., Masilela, Mduduzi, Mathew, Moncy, Meijs, Wilma, Morris, Susan, Mpelembue, Mushiya, Noal, Helena, Nugent, Fay L., O'Connor, Daniel, Olchawski, Victoria, O'Reilly, Paula, Phillips, Daniel J., Pickup, Lorinda, Du Plessis, Joan, Pollard, Samuel, Poulton, Ian, Pulido, David, Reiné, Jesús, Resuello-Dauti, Mila, Richter, Alex, Roche, Sophie, Rollier, Christine, Ruiz, Sarah, Sala, Claudia, Sanchez-Gonzalez, Amada, Sharpe, Hannah E., Smith, Daniel C., Smith, Holly E., Soares, Tiago, Souza, Cinthia M.C.D.L., Spina, Fernanda, Steven, Jill, Stockdale, Lisa, Stockwell, Lisa V., Sturdy, Ann, Tarr, Alexander W., Taylor, Ursula, Themistocleous, Andreas, Tsheko, Betty Lebogang, Turabi, Aadil, Waddington, Claire S., Wallis, Erica, Webb, Stewart

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Effect of Intravenous Tenecteplase Dose on Cerebral Reperfusion Before Thrombectomy in Patients With Large Vessel Occlusion Ischemic Stroke: The EXTEND-IA TNK Part 2 Randomized Cli... von Campbell, Bruce C. V, Mitchell, Peter J, Churilov, Leonid, Yassi, Nawaf, Kleinig, Timothy J, Dowling, Richard J, Yan, Bernard, Bush, Steven J, Thijs, Vincent, Scroop, Rebecca, Simpson, Marion, Brooks, Mark, Asadi, Hamed, Wu, Teddy Y, Shah, Darshan G, Wijeratne, Tissa, Zhao, Henry, Alemseged, Fana, Ng, Felix, Bailey, Peter, Rice, Henry, de Villiers, Laetitia, Dewey, Helen M, Choi, Philip M. C, Brown, Helen, Redmond, Kendal, Leggett, David, Fink, John N, Collecutt, Wayne, Kraemer, Thomas, Krause, Martin, Cordato, Dennis, Field, Deborah, Ma, Henry, O’Brien, Bill, Clissold, Benjamin, Miteff, Ferdinand, Clissold, Anna, Cloud, Geoffrey C, Bolitho, Leslie E, Bonavia, Luke, Bhattacharya, Arup, Wright, Alistair, Mamun, Abul, O’Rourke, Fintan, Worthington, John, Wong, Andrew A, Levi, Christopher R, Bladin, Christopher F, Sharma, Gagan, Desmond, Patricia M, Parsons, Mark W, Donnan, Geoffrey A, Davis, Stephen M

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Long‐Term Electrical and Mechanical Function Monitoring of a Human‐on‐a‐Chip System von Oleaga, Carlota, Lavado, Andrea, Riu, Anne, Rothemund, Sandra, Carmona‐Moran, Carlos A., Persaud, Keisha, Yurko, Andrew, Lear, Jennifer, Narasimhan, Narasimhan Sriram, Long, Christopher J., Sommerhage, Frank, Bridges, Lee Richard, Cai, Yunqing, Martin, Candace, Schnepper, Mark T., Goswami, Arindom, Note, Reine, Langer, Jessica, Teissier, Silvia, Cotovio, José, Hickman, James J.

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X-ray Diffraction Results from Mars Science Laboratory: Mineralogy of Rocknest at Gale Crater von Bish, D. L., Blake, D. F., Vaniman, D. T., Chipera, S. J., Morris, R. V., Ming, D. W., Treiman, A. H., Sarrazin, P., Morrison, S. M., Downs, R. T., Achilles, C. N., Yen, A. S., Bristow, T. F., Crisp, J. A., Morookian, J. M., Farmer, J. D., Rampe, E. B., Stolper, E. M., Spanovich, N.

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