VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research von Lai, Zhongwu, Markovets, Aleksandra, Ahdesmaki, Miika, Chapman, Brad, Hofmann, Oliver, McEwen, Robert, Johnson, Justin, Dougherty, Brian, Barrett, J Carl, Dry, Jonathan R

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Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes von Hodgson, Darren R., Dougherty, Brian A., Lai, Zhongwu, Fielding, Anitra, Grinsted, Lynda, Spencer, Stuart, O’Connor, Mark J., Ho, Tony W., Robertson, Jane D., Lanchbury, Jerry S., Timms, Kirsten M., Gutin, Alexander, Orr, Maria, Jones, Helen, Gilks, Blake, Womack, Chris, Gourley, Charlie, Ledermann, Jonathan, Barrett, J. Carl

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Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M von Thress, Kenneth S, Paweletz, Cloud P, Felip, Enriqueta, Cho, Byoung Chul, Stetson, Daniel, Dougherty, Brian, Lai, Zhongwu, Markovets, Aleksandra, Vivancos, Ana, Kuang, Yanan, Ercan, Dalia, Matthews, Sarah E, Cantarini, Mireille, Barrett, J Carl, Jänne, Pasi A, Oxnard, Geoffrey R

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Capivasertib Plus Paclitaxel Versus Placebo Plus Paclitaxel As First-Line Therapy for Metastatic Triple-Negative Breast Cancer: The PAKT Trial von Schmid, Peter, Abraham, Jacinta, Chan, Stephen, Wheatley, Duncan, Brunt, Adrian Murray, Nemsadze, Gia, Baird, Richard D, Park, Yeon Hee, Hall, Peter S, Perren, Timothy, Stein, Robert C, Mangel, László, Ferrero, Jean-Marc, Phillips, Melissa, Conibear, John, Cortes, Javier, Foxley, Andrew, de Bruin, Elza C, McEwen, Robert, Stetson, Daniel, Dougherty, Brian, Sarker, Shah-Jalal, Prendergast, Aaron, McLaughlin-Callan, Max, Burgess, Matthew, Lawrence, Cheryl, Cartwright, Hayley, Mousa, Kelly, Turner, Nicholas C

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Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phas... von Ledermann, Jonathan, Prof, Harter, Philipp, MD, Gourley, Charlie, Prof, Friedlander, Michael, Prof, Vergote, Ignace, Prof, Rustin, Gordon, Prof, Scott, Clare L, PhD, Meier, Werner, Prof, Shapira-Frommer, Ronnie, MD, Safra, Tamar, MD, Matei, Daniela, MD, Fielding, Anitra, MBChB, Spencer, Stuart, MSc, Dougherty, Brian, PhD, Orr, Maria, PhD, Hodgson, Darren, PhD, Barrett, J Carl, PhD, Matulonis, Ursula, MD

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Long-Term Responders on Olaparib Maintenance in High-Grade Serous Ovarian Cancer: Clinical and Molecular Characterization von Lheureux, Stephanie, Lai, Zhongwu, Dougherty, Brian A, Runswick, Sarah, Hodgson, Darren R, Timms, Kirsten M, Lanchbury, Jerry S, Kaye, Stan, Gourley, Charlie, Bowtell, David, Kohn, Elise C, Scott, Claire, Matulonis, Ursula, Panzarella, Tony, Karakasis, Katherine, Burnier, Julia V, Gilks, C Blake, O'Connor, Mark J, Robertson, Jane D, Ledermann, Jonathan, Barrett, J Carl, Ho, Tony W, Oza, Amit M

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Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase 2 trial von Oza, Amit M, Prof, Cibula, David, Prof, Benzaquen, Ana Oaknin, MD, Poole, Christopher, Prof, Mathijssen, Ron H J, Prof, Sonke, Gabe S, MD, Colombo, Nicoletta, MD, Špaček, Jiří, MD, Vuylsteke, Peter, MD, Hirte, Holger, MD, Mahner, Sven, MD, Plante, Marie, MD, Schmalfeldt, Barbara, Prof, Mackay, Helen, MD, Rowbottom, Jacqui, PhD, Lowe, Elizabeth S, MD, Dougherty, Brian, PhD, Barrett, J Carl, PhD, Friedlander, Michael, Prof

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Biological and clinical evidence for somatic mutations in BRCA1 and BRCA2 as predictive markers for olaparib response in high-grade serous ovarian cancers in the maintenance settin... von Dougherty, Brian A, Lai, Zhongwu, Hodgson, Darren R, Orr, Maria C M, Hawryluk, Matthew, Sun, James, Yelensky, Roman, Spencer, Stuart K, Robertson, Jane D, Ho, Tony W, Fielding, Anitra, Ledermann, Jonathan A, Barrett, J Carl

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Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer von Tcyganov, Evgenii N, Hanabuchi, Shino, Hashimoto, Ayumi, Campbell, David, Kar, Gozde, Slidel, Timothy W.F, Cayatte, Corinne, Landry, Aimee, Pilataxi, Fernanda, Hayes, Susana, Dougherty, Brian, Hicks, Kristin C, Mulgrew, Kathy, Tang, Chih- Hang Anthony, Hu, Chih-Chi Andrew, Guo, Wei, Grivennikov, Sergei, Ali, Mohammed-Alkhatim A, Beltra, Jean-Christophe, Wherry, E. John, Nefedova, Yulia, Gabrilovich, Dmitry I

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Generation of stable PDX derived cell lines using conditional reprogramming von Borodovsky, Alexandra, McQuiston, Travis J, Stetson, Daniel, Ahmed, Ambar, Whitston, David, Zhang, Jingwen, Grondine, Michael, Lawson, Deborah, Challberg, Sharon S, Zinda, Michael, Pollok, Brian A, Dougherty, Brian A, D'Cruz, Celina M

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Genetic Organization of Transposase Regions Surrounding blaKPC Carbapenemase Genes on Plasmids from Klebsiella Strains Isolated in a New York City Hospital von Gootz, Thomas D, Lescoe, Mary Kay, Dib-Hajj, Fadia, Dougherty, Brian A, He, Wen, Della-Latta, Phyllis, Huard, Richard C

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Defining actionable mutations for oncology therapeutic development von Carr, T. Hedley, McEwen, Robert, Dougherty, Brian, Johnson, Justin H., Dry, Jonathan R., Lai, Zhongwu, Ghazoui, Zara, Laing, Naomi M., Hodgson, Darren R., Cruzalegui, Francisco, Hollingsworth, Simon J., Barrett, J. Carl

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Concordance of BRCA mutation detection in tumor versus blood, and frequency of bi-allelic loss of BRCA in tumors from patients in the phase III SOLO2 trial von Hodgson, Darren R., Brown, Jessica S., Dearden, Simon P., Lai, Zhongwu, Elks, Cathy E., Milenkova, Tsveta, Dougherty, Brian A., Lanchbury, Jerry S., Perry, Michael, Timms, Kirsten M., Harrington, Elizabeth A., Barrett, J. Carl, Leary, Alexandra, Pujade-Lauraine, Eric

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Evaluation and Validation of Equivalent Circuit Photovoltaic Solar Cell Performance Models von Boyd, Matthew T, Klein, Sanford A, Reindl, Douglas T, Dougherty, Brian P

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Midwestern cropping system effects on drainage water quality and crop yields von Dougherty, Brian W., Pederson, Carl H., Mallarino, Antonio P., Andersen, Daniel S., Soupir, Michelle L., Kanwar, Ramesh S., Helmers, Matthew J.

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Comparison of the Acute Metabolic Responses to Traditional Resistance, Body-Weight, and Battling Rope Exercises von Ratamess, Nicholas A, Rosenberg, Joseph G, Klei, Samantha, Dougherty, Brian M, Kang, Jie, Smith, Charles R, Ross, Ryan E, Faigenbaum, Avery D

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Identification of 113 conserved essential genes using a high‐throughput gene disruption system in Streptococcus pneumoniae von Thanassi, Jane A., Hartman‐Neumann, Sandra L., Dougherty, Thomas J., Dougherty, Brian A., Pucci, Michael J.

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Liquid Swine Manure Application Variability: Challenges and Opportunities von Dougherty, Brian W., Andersen, Daniel Steven, Helmers, Matthew J.

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Comparative analysis of primary versus relapse/refractory DLBCL identifies shifts in mutation spectrum von Greenawalt, Danielle M, Liang, Winnie S, Saif, Sakina, Johnson, Justin, Todorov, Petar, Dulak, Austin, Enriquez, Daniel, Halperin, Rebecca, Ahmed, Ambar, Saveliev, Vladislav, Carpten, John, Craig, David, Barrett, J Carl, Dougherty, Brian, Zinda, Michael, Fawell, Stephen, Dry, Jonathan R, Byth, Kate

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Genes contributing to pain sensitivity in the normal population: an exome sequencing study von Williams, Frances M K, Scollen, Serena, Cao, Dandan, Memari, Yasin, Hyde, Craig L, Zhang, Baohong, Sidders, Benjamin, Ziemek, Daniel, Shi, Yujian, Harris, Juliette, Harrow, Ian, Dougherty, Brian, Malarstig, Anders, McEwen, Robert, Stephens, Joel C, Patel, Ketan, Menni, Cristina, Shin, So-Youn, Hodgkiss, Dylan, Surdulescu, Gabriela, He, Wen, Jin, Xin, McMahon, Stephen B, Soranzo, Nicole, John, Sally, Wang, Jun, Spector, Tim D

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