Reduction of exacerbations by the PDE4 inhibitor roflumilast--the importance of defining different subsets of patients with COPD von Rennard, Stephen I, Calverley, Peter M A, Goehring, Udo M, Bredenbröker, Dirk, Martinez, Fernando J

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Cardiovascular Safety in Patients Receiving Roflumilast for the Treatment of COPD von White, William B., MD, Cooke, Glen E., MD, Kowey, Peter R., MD, Calverley, Peter M.A., MD, Bredenbröker, Dirk, MD, Goehring, Udo-Michael, MD, Zhu, Haiyuan, PhD, Lakkis, Hassan, PhD, Mosberg, Hans, MD, Rowe, Paul, MD, Rabe, Klaus F., MD, PhD

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Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects von Gauvreau, Gail M, Boulet, Louis-Philippe, Schmid-Wirlitsch, Christine, Côté, Johanne, Duong, Mylinh, Killian, Kieran J, Milot, Joanne, Deschesnes, Francine, Strinich, Tara, Watson, Richard M, Bredenbröker, Dirk, O'Byrne, Paul M

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Roflumilast—an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial von Rabe, Klaus F, Bateman, Eric D, O'Donnell, Denis, Witte, Stephan, Bredenbröker, Dirk, Bethke, Thomas D

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Physiological effects of roflumilast at rest and during exercise in COPD von O'DONNELL, Denis E, BREDENBRÖKER, Dirk, BROSE, Manja, WEBB, Katherine A

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Efficacy of Roflumilast in the COPD Frequent Exacerbator Phenotype von Wedzicha, Jadwiga A., MD, Rabe, Klaus F., MD, Martinez, Fernando J., MD, Bredenbröker, Dirk, MD, Brose, Manja, MS, Goehring, Udo-Michael, MD, Calverley, Peter M.A., MD

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Roflumilast and dyspnea in patients with moderate to very severe chronic obstructive pulmonary disease: a pooled analysis of four clinical trials von Rennard, Stephen I, Sun, Shawn X, Tourkodimitris, Stavros, Rowe, Paul, Goehring, Udo M, Bredenbröker, Dirk, Calverley, Peter M A

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Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD von Grootendorst, Diana C, Gauw, Stefanie A, Verhoosel, Renate M, Sterk, Peter J, Hospers, Jeannette J, Bredenbröker, Dirk, Bethke, Thomas D, Hiemstra, Pieter S, Rabe, Klaus F

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Response von Wedzicha, Jadwiga A., Rabe, Klaus F., Martinez, Fernando J., Bredenbröker, Dirk, Brose, Manja, Goehring, Udo-Michael, Calverley, Peter M.A.

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Roflumilast, an oral, once-daily phosphodiesterase 4 inhibitor, attenuates allergen-induced asthmatic reactions von van Schalkwyk, Emmerentia, Strydom, K., Williams, Zelda, Venter, Louis, Leichtl, Stefan, Schmid-Wirlitsch, Christine, Bredenbröker, Dirk, Bardin, Philip G.

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Response von Wedzicha, Jadwiga A., MD, Rabe, Klaus F., MD, Martinez, Fernando J., MD, Bredenbröker, Dirk, MD, Brose, Manja, MS, Goehring, Udo-Michael, MD, Calverley, Peter M.A., MD

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The Effect of Roflumilast on Lung Function: Pooled Results From Seven 6-Month Studies in Subjects With Moderate-to-Severe COPD von Hanania, Nicola, MD, Karpel, Jill, MD, Goehring, Udo-Michael, MD, Brose, Manja, MS, Bredenbroker, Dirk, MD, Lakkis, Hassan, PhD, Rowe, Paul, MD, Fabbri, Leonardo, MD

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Respiratory-Associated Adverse Events in the Roflumilast COPD Safety Pool von Ferguson, Gary, MD, Hanania, Nicola, MD, Goehring, Udo-Michael, MD, Mosberg, Hans, MD, Brose, Manja, MS, Bredenbroker, Dirk, MD, Lakkis, Hassan, PhD, Rowe, Paul, MD

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Roflumilast in Asian patients with COPD: A randomized placebo-controlled trial von LEE, SANG-DO, HUI, DAVID S. C., MAHAYIDDIN, AZIAH A., ROA JR, CAMILO C., KWA, KHENG HOE, GOEHRING, UDO-MICHAEL, BREDENBRÖKER, DIRK, KUO, HAN-PIN

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Efficacy and safety of roflumilast in the treatment of asthma von Bateman, Eric D., Izquierdo, Jose L., Harnest, Ulf, Hofbauer, Peter, Magyar, Pal, Schmid-Wirlitsch, Christine, Leichtl, Stefan, Bredenbröker, Dirk

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Response von Wedzicha, Jadwiga A, Rabe, Klaus F, Martinez, Fernando J, Bredenbröker, Dirk, Brose, Manja, Goehring, Udo-Michael, Calverley, Peter M A

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Response von Wedzicha, Jadwiga A, Rabe, Klaus F, Martinez, Fernando J, Bredenbröker, Dirk, Brose, Manja, Goehring, Udo-Michael, Calverley, Peter M A

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Effects of the nitric oxide/cGMP system compared with the cAMP system on airway mucus secretion in the rat von Bredenbröker, Dirk, Dyarmand, Darius, Meingast, Uta, Fehmann, Hans-Christoph, Staats, Petra, Von Wichert, Peter, Wagner, Ulrich

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Effects of VIP and Related Peptides on Airway Mucus Secretion from Isolated Rat Trachea von Wagner, Ulrich, Bredenbröker, Dirk, Storm, Burkhard, Tackenberg, Björn, Fehmann, Hans-Christoph, von Wichert, Peter

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Effects of selective and non-selective phosphodiesterase inhibitors on tracheal mucus secretion in the rat von Wagner, Ulrich, Bredenbröker, Dirk, Fehmann, Hans-Christoph, Schwarz, Friederike, Schudt, Christian, Von Wichert, Peter

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