Single Gene Prognostic Biomarkers in Ovarian Cancer: A Meta-Analysis von Willis, Scooter, Villalobos, Victor M, Gevaert, Olivier, Abramovitz, Mark, Williams, Casey, Sikic, Branimir I, Leyland-Jones, Brian

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First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers von Sikic, Branimir I, Lakhani, Nehal, Patnaik, Amita, Shah, Sumit A, Chandana, Sreenivasa R, Rasco, Drew, Colevas, A Dimitrios, O'Rourke, Timothy, Narayanan, Sujata, Papadopoulos, Kyriakos, Fisher, George A, Villalobos, Victor, Prohaska, Susan S, Howard, Maureen, Beeram, Muralidhar, Chao, Mark P, Agoram, Balaji, Chen, James Y, Huang, Jie, Axt, Matthew, Liu, Jie, Volkmer, Jens-Peter, Majeti, Ravindra, Weissman, Irving L, Takimoto, Chris H, Supan, Dana, Wakelee, Heather A, Aoki, Rhonda, Pegram, Mark D, Padda, Sukhmani K

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Molecular Pathways: Regulation and Therapeutic Implications of Multidrug Resistance von CHEN, Kevin G, SIKIC, Branimir I

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A clinical trial of zosuquidar plus gemtuzumab ozogamicin (GO) in relapsed or refractory acute myeloid leukemia (RR AML): evidence of efficacy based on leukemic blast P-glycoprotei... von Marcelletti, John F., Sikic, Branimir I.

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Continuous 72-h infusion of zosuquidar with chemotherapy in patients with newly diagnosed acute myeloid leukemia stratified for leukemic blast P-glycoprotein phenotype von Marcelletti, John F., Sikic, Branimir I.

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The Syk inhibitor R406 is a modulator of P-glycoprotein (ABCB1)-mediated multidrug resistance von Duran, George E, Sikic, Branimir I

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Safety, tolerability and efficacy of agonist anti-CD27 antibody (varlilumab) administered in combination with anti-PD-1 (nivolumab) in advanced solid tumors von Sanborn, Rachel E, Pishvaian, Michael J, Callahan, Margaret K, Weise, Amy, Sikic, Branimir I, Rahma, Osama, Cho, Daniel C, Rizvi, Naiyer A, Sznol, Mario, Lutzky, Jose, Bauman, Julie E, Bitting, Rhonda L, Starodub, Alexander, Jimeno, Antonio, Reardon, David A, Kaley, Thomas, Iwamoto, Fabio, Baehring, Joachim M, Subramaniam, Deepa S, Aragon-Ching, Jeanny B, Hawthorne, Thomas R, Rawls, Tracey, Yellin, Michael, Keler, Tibor

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The miR-200 family differentially regulates sensitivity to paclitaxel and carboplatin in human ovarian carcinoma OVCAR-3 and MES-OV cells von Brozovic, Anamaria, Duran, George E., Wang, Yan C., Francisco, E. Brian, Sikic, Branimir I.

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Decreased levels of baseline and drug-induced tubulin polymerisation are hallmarks of resistance to taxanes in ovarian cancer cells and are associated with epithelial-to-mesenchyma... von Duran, George E, Wang, Yan C, Moisan, François, Francisco, E Brian, Sikic, Branimir I

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Mechanisms of resistance to cabazitaxel von Duran, George E, Wang, Yan C, Francisco, E Brian, Rose, John C, Martinez, Francisco J, Coller, John, Brassard, Diana, Vrignaud, Patricia, Sikic, Branimir I

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Safety and Activity of Varlilumab, a Novel and First-in-Class Agonist Anti-CD27 Antibody, in Patients With Advanced Solid Tumors von Burris, Howard A, Infante, Jeffrey R, Ansell, Stephen M, Nemunaitis, John J, Weiss, Geoffrey R, Villalobos, Victor M, Sikic, Branimir I, Taylor, Matthew H, Northfelt, Donald W, Carson, 3rd, William E, Hawthorne, Thomas R, Davis, Thomas A, Yellin, Michael J, Keler, Tibor, Bullock, Timothy

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Safety and activity of varlilumab, a novel and first-in-class agonist anti-CD27 antibody, for hematologic malignancies von Ansell, Stephen M., Flinn, Ian, Taylor, Matthew H., Sikic, Branimir I., Brody, Joshua, Nemunaitis, John, Feldman, Andrew, Hawthorne, Thomas R., Rawls, Tracey, Keler, Tibor, Yellin, Michael J.

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Cabazitaxel is more active than first-generation taxanes in ABCB1(+) cell lines due to its reduced affinity for P-glycoprotein von Duran, George E., Derdau, Volker, Weitz, Dietmar, Philippe, Nicolas, Blankenstein, Jörg, Atzrodt, Jens, Sémiond, Dorothée, Gianolio, Diego A., Macé, Sandrine, Sikic, Branimir I.

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Carboplatin-induced upregulation of pan β-tubulin and class III β-tubulin is implicated in acquired resistance and cross-resistance of ovarian cancer von Pernar Kovač, Margareta, Tadić, Vanja, Kralj, Juran, Duran, George E., Stefanelli, Alessia, Stupin Polančec, Darija, Dabelić, Sanja, Bačić, Niko, Tomicic, Maja T., Heffeter, Petra, Sikic, Branimir I., Brozovic, Anamaria

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A Network Model of a Cooperative Genetic Landscape in Brain Tumors von Bredel, Markus, Scholtens, Denise M, Harsh, Griffith R, Bredel, Claudia, Chandler, James P, Renfrow, Jaclyn J, Yadav, Ajay K, Vogel, Hannes, Scheck, Adrienne C, Tibshirani, Robert, Sikic, Branimir I

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Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas von Bredel, Markus, Bredel, Claudia, Juric, Dejan, Harsh, Griffith R, Vogel, Hannes, Recht, Lawrence D, Sikic, Branimir I

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Enhancement of paclitaxel and carboplatin therapies by CCL2 blockade in ovarian cancers von Moisan, Francois, Francisco, Edgar B., Brozovic, Anamaria, Duran, George E., Wang, Yan C., Chaturvedi, Shalini, Seetharam, Shobha, Snyder, Linda A., Doshi, Parul, Sikic, Branimir I.

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Chromatin-Remodeling Complex SWI/SNF Controls Multidrug Resistance by Transcriptionally Regulating the Drug Efflux Pump ABCB1 von Dubey, Ramin, Lebensohn, Andres M, Bahrami-Nejad, Zahra, Marceau, Caleb, Champion, Magali, Gevaert, Olivier, Sikic, Branimir I, Carette, Jan E, Rohatgi, Rajat

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A first-in-human phase I study to evaluate the MEK1/2 inhibitor, cobimetinib, administered daily in patients with advanced solid tumors von Rosen, Lee S., LoRusso, Patricia, Ma, Wen Wee, Goldman, Jonathan W., Weise, Amy, Colevas, A. Dimitrios, Adjei, Alex, Yazji, Salim, Shen, Angela, Johnston, Stuart, Hsieh, Hsin-Ju, Chan, Iris T., Sikic, Branimir I.

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NFKBIA Deletion in Glioblastomas von Bredel, Claudia, Bredel, Markus, Scholtens, Denise M, Yadav, Ajay K, Alvarez, Angel A, Renfrow, Jaclyn J, Chandler, James P, Yu, Irene L.Y, Carro, Maria S, Dai, Fangping, Tagge, Michael J, Ferrarese, Roberto, Phillips, Heidi S, Lukac, Paul J, Robe, Pierre A, Weyerbrock, Astrid, Vogel, Hannes, Dubner, Steven, Mobley, Bret, He, Xiaolin, Scheck, Adrienne C, Sikic, Branimir I, Aldape, Kenneth D, Chakravarti, Arnab, Harsh, Griffith R

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