Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates von Frank-Kamenetsky, Maria, Grefhorst, Aldo, Anderson, Norma N, Racie, Timothy S, Bramlage, Birgit, Akinc, Akin, Butler, David, Charisse, Klaus, Dorkin, Robert, Fan, Yupeng, Gamba-Vitalo, Christina, Hadwiger, Philipp, Jayaraman, Muthusamy, John, Matthias, Jayaprakash, K. Narayanannair, Maier, Martin, Nechev, Lubomir, Rajeev, Kallanthottathil G, Read, Timothy, Röhl, Ingo, Soutschek, Jürgen, Tan, Pamela, Wong, Jamie, Wang, Gang, Zimmermann, Tracy, de Fougerolles, Antonin, Vornlocher, Hans-Peter, Langer, Robert, Anderson, Daniel G, Manoharan, Muthiah, Koteliansky, Victor, Horton, Jay D, Fitzgerald, Kevin

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Targeted siRNA Delivery and mRNA Knockdown Mediated by Bispecific Digoxigenin-binding Antibodies von Schneider, Britta, Grote, Michael, John, Matthias, Haas, Alexander, Bramlage, Birgit, lckenstein, Ludger M, Jahn-Hofmann, Kerstin, Bauss, Frieder, Cheng, Weijun, Croasdale, Rebecca, Daub, Karin, Dill, Simone, Hoffmann, Eike, Lau, Wilma, Burtscher, Helmut, Ludtke, James L, Metz, Silke, Mundigl, Olaf, Neal, Zane C, Scheuer, Werner, Stracke, Jan, Herweijer, Hans, Brinkmann, Ulrjch

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs von Soutschek, Jürgen, Akinc, Akin, Bramlage, Birgit, Charisse, Klaus, Constien, Rainer, Donoghue, Mary, Elbashir, Sayda, Geick, Anke, Hadwiger, Philipp, Harborth, Jens, John, Matthias, Kesavan, Venkitasamy, Lavine, Gary, Pandey, Rajendra K, Racie, Timothy, Rajeev, Kallanthottathil G, Röhl, Ingo, Toudjarska, Ivanka, Wang, Gang, Wuschko, Silvio, Bumcrot, David, Koteliansky, Victor, Limmer, Stefan, Manoharan, Muthiah, Vornlocher, Hans-Peter

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Differential expression of the murine histone genes H3.3A and H3.3B von Bramlage, Birgit, Kosciessa, Ulrich, Doenecke, Detlef

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Characterization of a monoclonal antibody with specificity for holo-transcobalamin von Orning, Lars, Rian, Anne, Campbell, Andrew, Brady, Jeff, Fedosov, Sergey N, Bramlage, Birgit, Thompson, Keith, Quadros, Edward V

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RNAi-mediated gene silencing in non-human primates von Wheat, Amanda J, Vornlocher, Hans-Peter, Röhl, Ingo, Lam, Kieu, McClintock, Kevin, Koteliansky, Victor, Yaworski, Ed, Jeffs, Lloyd B, MacLachlan, Ian, Soutschek, Jürgen, Toudjarska, Ivanka, Palmer, Lorne R, Heyes, James A, Zedalis, William, Akinc, Akin, Lee, Amy C. H, Bumcrot, David, Manoharan, Muthiah, Judge, Adam D, Racie, Timothy, Shanmugam, Sumi, Sood, Vandana, Seiffert, Stephan, Bramlage, Birgit, Fedoruk, Matthew N, Harborth, Jens, Zimmermann, Tracy S, John, Matthias, Nechev, Lubomir V

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HIV-1 LTR as a target for synthetic ribozyme-mediated inhibition of gene expression: site selection and inhibition in cell culture von Bramlage, B, Luzi, E, Eckstein, F

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Designing ribozymes for the inhibition of gene expression von Bramlage, Birgit, Luzi, Ettore, Eckstein, Fritz

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Expression of the mouse testicular histone gene H1t during spermatogenesis von Drabent, B, Bode, C, Bramlage, B, Doenecke, D

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Compositions and methods for inhibiting expression of RRM2 genes von Bramlage, Birgit, Hossbach, Markus, Boylan, John Frederick, Reidhaar-Olson, John

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Abstract 583: RNAi Therapeutics For The Lowering Of Cholesterol von Fitzgerald, Kevin, Frank-Kamenetsky, Maria, Zimmermann, Tracy S, Horton, Jay, Akinc, Akin, Bramlage, Birgit, Bumcrot, David, Harborth, Jens, John, Matthias, Kotelianski, Victor, Manoharan, Muthiah, Maier, Martin, Nechev, Lubomir, Racie, Timothy, Roehl, Ingo, Seiffert, Stephan, Shanmugam, Sumi, Soutschek, Jurgen, Toudjarska, Ivanka, Vornlocher, Hans-Peter, Zedalis, William

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COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE PCSK9 GENE von Frank-Kamenetsky, Maria, Bramlage, Birgit, Tan, Pamela, Kotelianski, Victor E, Fitzgerald, Kevin, Akinc, Akin

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Inhibition of luciferase expression by synthetic hammerhead ribozymes and their cellular uptake von Bramlage, Birgit, Alefelder, Stefan, Marschall, Peter, Eckstein, Fritz

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The hammerhead ribozyme von Eckstein, Fritz, Bramlage, Birgit

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Compositions and Methods for Inhibiting Expression of RRM2 Genes von Bramlage, Birgit, Hossbach, Markus, Boylan, John Frederick, Reidhaar-Olson, John

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Compositions and methods for inhibiting expression of RRM2 genes von Bramlage, Birgit, Hossbach, Markus, Boylan, John Frederick, Reidhaar-Olson, John

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COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE PCSK9 GENE von Frank-Kamenetsky, Maria, Bramlage, Birgit, Tan, Pamela, Kotelianski, Victor E, Fitzgerald, Kevin, Akinc, Akin

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COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE PCSK9 GENE von AKINC, Akin, BRAMLAGE, Birgit, KOTELIANSKI, Victor E, TAN, Pamela, FRANK-KAMENETSKY, Maria, FITZGERALD, Kevin

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COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE PCSK9 GENE von TAN, PAMELA, AKINC, AKIN, KOTELIANSKI, VICTOR E, FITZGERALD, KEVIN, FRANK-KAMENETSKY, MARIA, BRAMLAGE, BIRGIT

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The Human Replacement Histone H3.3B Gene (H3F3B) von Albig, Werner, Bramlage, Birgit, Gruber, Konstanze, Klobeck, Hans-Gustav, Kunz, Jürgen, Doenecke, Detlef

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