Ibrutinib–Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia von Shanafelt, Tait D, Wang, Xin V, Kay, Neil E, Hanson, Curtis A, O’Brien, Susan, Barrientos, Jacqueline, Jelinek, Diane F, Braggio, Esteban, Leis, Jose F, Zhang, Cong C, Coutre, Steven E, Barr, Paul M, Cashen, Amanda F, Mato, Anthony R, Singh, Avina K, Mullane, Michael P, Little, Richard F, Erba, Harry, Stone, Richard M, Litzow, Mark, Tallman, Martin

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Long-term outcomes for ibrutinib-rituximab and chemoimmunotherapy in CLL: updated results of the E1912 trial von Shanafelt, Tait D, Wang, Xin Victoria, Hanson, Curtis A, Paietta, Elisabeth M, O'Brien, Susan, Barrientos, Jacqueline, Jelinek, Diane F, Braggio, Esteban, Leis, Jose F, Zhang, Cong Christine, Coutre, Steven E, Barr, Paul M, Cashen, Amanda F, Mato, Anthony R, Singh, Avina K, Mullane, Michael P, Little, Richard F, Erba, Harry, Stone, Richard M, Litzow, Mark, Tallman, Martin, Kay, Neil E

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Loss of FAM46C Promotes Cell Survival in Myeloma von Zhu, Yuan Xiao, Shi, Chang-Xin, Bruins, Laura A, Jedlowski, Patrick, Wang, Xuewei, Kortüm, K Martin, Luo, Moulun, Ahmann, Jonathan M, Braggio, Esteban, Stewart, A Keith

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Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes von Kortüm, K.Martin, Mai, Elias K., Hanafiah, Nur H., Shi, Chang-Xi, Zhu, Yuan-Xiao, Bruins, Laura, Barrio, Santiago, Jedlowski, Patrick, Merz, Maximilian, Xu, Jing, Stewart, Robert A., Andrulis, Mindaugas, Jauch, Anna, Hillengass, Jens, Goldschmidt, Hartmut, Bergsagel, P.Leif, Braggio, Esteban, Stewart, A.Keith, Raab, Marc S.

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Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide von Zhu, Yuan Xiao, Braggio, Esteban, Shi, Chang-Xin, Bruins, Laura A., Schmidt, Jessica E., Van Wier, Scott, Chang, Xiu-Bao, Bjorklund, Chad C., Fonseca, Rafael, Bergsagel, P. Leif, Orlowski, Robert Z., Stewart, A. Keith

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Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas von Braggio, Esteban, Van Wier, Scott, Ojha, Juhi, McPhail, Ellen, Asmann, Yan W, Egan, Jan, da Silva, Jackline Ayres, Schiff, David, Lopes, M Beatriz, Decker, Paul A, Valdez, Riccardo, Tibes, Raoul, Eckloff, Bruce, Witzig, Thomas E, Stewart, A Keith, Fonseca, Rafael, O'Neill, Brian Patrick

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Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides von Egan, Jan B., Shi, Chang-Xin, Tembe, Waibhav, Christoforides, Alexis, Kurdoglu, Ahmet, Sinari, Shripad, Middha, Sumit, Asmann, Yan, Schmidt, Jessica, Braggio, Esteban, Keats, Jonathan J., Fonseca, Rafael, Bergsagel, P. Leif, Craig, David W., Carpten, John D., Stewart, A. Keith

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Precancer Atlas to Drive Precision Prevention Trials von Spira, Avrum, Yurgelun, Matthew B, Alexandrov, Ludmil, Rao, Anjana, Bejar, Rafael, Polyak, Kornelia, Giannakis, Marios, Shilatifard, Ali, Finn, Olivera J, Dhodapkar, Madhav, Kay, Neil E, Braggio, Esteban, Vilar, Eduardo, Mazzilli, Sarah A, Rebbeck, Timothy R, Garber, Judy E, Velculescu, Victor E, Disis, Mary L, Wallace, Douglas C, Lippman, Scott M

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Novel Richter Syndrome Xenograft Models to Study Genetic Architecture, Biology, and Therapy Responses von Vaisitti, Tiziana, Braggio, Esteban, Allan, John N, Arruga, Francesca, Serra, Sara, Zamò, Alberto, Tam, Wayne, Chadburn, Amy, Furman, Richard R, Deaglio, Silvia

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Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4 von Zhu, Yuan Xiao, Shi, Chang-Xin, Bruins, Laura A., Wang, Xuewei, Riggs, Daniel L., Porter, Brooke, Ahmann, Jonathan M., de Campos, Cecilia Bonolo, Braggio, Esteban, Bergsagel, P. Leif, Stewart, A. Keith

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CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma von Shi, Chang-Xin, Kortüm, K Martin, Zhu, Yuan Xiao, Bruins, Laura A, Jedlowski, Patrick, Votruba, Patrick G, Luo, Moulun, Stewart, Robert A, Ahmann, Jonathan, Braggio, Esteban, Stewart, A Keith

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The genomic landscape of VkMYC myeloma highlights shared pathways of transformation between mice and humans von Maura, Francesco, Coffey, David G., Stein, Caleb K., Braggio, Esteban, Ziccheddu, Bachisio, Sharik, Meaghen E., Du, Megan T., Tafoya Alvarado, Yuliza, Shi, Chang-Xin, Zhu, Yuan Xiao, Meermeier, Erin W., Morgan, Gareth J., Landgren, Ola, Bergsagel, P. Leif, Chesi, Marta

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Hypodiploid multiple myeloma is characterized by more aggressive molecular markers than non-hyperdiploid multiple myeloma von Van Wier, Scott, Braggio, Esteban, Baker, Angela, Ahmann, Gregory, Levy, Joan, Carpten, John D, Fonseca, Rafael

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KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival von Vendramini, Elena, Bomben, Riccardo, Pozzo, Federico, Benedetti, Dania, Bittolo, Tamara, Rossi, Francesca Maria, Dal Bo, Michele, Rabe, Kari G., Pozzato, Gabriele, Zaja, Francesco, Chiarenza, Annalisa, Di Raimondo, Francesco, Braggio, Esteban, Parikh, Sameer A., Kay, Neil E., Shanafelt, Tait D., Del Poeta, Giovanni, Gattei, Valter, Zucchetto, Antonella

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Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans von Kleinstern, Geffen, Weinberg, J. Brice, Parikh, Sameer A., Braggio, Esteban, Achenbach, Sara J., Robinson, Dennis P., Norman, Aaron D., Rabe, Kari G., Boddicker, Nicholas J., Vachon, Celine M., Lesnick, Connie E., Call, Timothy G., Brander, Danielle M., Rassenti, Laura Z., Kipps, Thomas J., Olson, Janet E., Cerhan, James R., Kay, Neil E., Furman, Richard R., Hanson, Curtis A., Shanafelt, Tait D., Slager, Susan L.

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MicroRNA and long non-coding RNA analysis in IgM-monoclonal gammopathies reveals epigenetic influence on cellular functions and oncogenesis von Chohan, Karan, Paludo, Jonas, Dasari, Surendra, Mondello, Patrizia, Novak, Joseph P, Abeykoon, Jithma P, Wenzl, Kerstin, Yang, Zhi-Zhang, Jalali, Shahrzad, Krull, Jordan E, Braggio, Esteban, Manske, Michelle K, Paulus, Aneel, Reeder, Craig B, Ailawadhi, Sikander, Chanan-Khan, Asher, Kapoor, Prashant, Kyle, Robert A, Gertz, Morie A, Novak, Anne J, Ansell, Stephen M

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Identification of PIKfyve kinase as a target in multiple myeloma von de Campos, Cecilia Bonolo, Zhu, Yuan Xiao, Sepetov, Nikolai, Romanov, Sergei, Bruins, Laura Ann, Shi, Chang-Xin, Stein, Caleb K., Petit, Joachim L., Polito, Alysia N., Sharik, Meaghen E., Meermeier, Erin W., Ahmann, Gregory J., Armenta, Ilsel D. Lopez, Kruse, Jonas, Bergsagel, P. Leif, Chesi, Marta, Meurice, Nathalie, Braggio, Esteban, Stewart, A. Keith

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Associations of history of vaccination and hospitalization due to infection with risk of monoclonal B-cell lymphocytosis von Boddicker, Nicholas J., Achenbach, Sara J., Parikh, Sameer A., Kleinstern, Geffen, Braggio, Esteban, Norman, Aaron D., Rabe, Kari G., Vachon, Celine M., Lesnick, Connie E., Call, Timothy G., Olson, Janet E., Cerhan, James R., Kay, Neil E., Hanson, Curtis A., Shanafelt, Tait D., Slager, Susan L.

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Evaluation of NUC-1031: a first-in-class ProTide in biliary tract cancer von Arora, Mansi, Bogenberger, James M., Abdelrahman, Amro, Leiting, Jennifer L., Chen, Xianfeng, Egan, Jan B., Kasimsetty, Aradhana, Lenkiewicz, Elzbieta, Malasi, Smriti, Uson, Pedro Luiz Serrano, Nagalo, Bolni Marius, Zhou, Yumei, Salomao, Marcela A., Kosiorek, Heidi E., Braggio, Esteban, Barrett, Michael T., Truty, Mark J., Borad, Mitesh J.

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Proteasome inhibitors block Ikaros degradation by lenalidomide in multiple myeloma von Shi, Chang-Xin, Kortüm, Klaus Martin, Zhu, Yuan Xiao, Jedlowski, Patrick, Bruins, Laura, Braggio, Esteban, Stewart, A Keith

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