A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development von Tang, Walfred W.C., Dietmann, Sabine, Irie, Naoko, Leitch, Harry G., Floros, Vasileios I., Bradshaw, Charles R., Hackett, Jamie A., Chinnery, Patrick F., Surani, M. Azim

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Human primary liver cancer–derived organoid cultures for disease modeling and drug screening von Broutier, Laura, Mastrogiovanni, Gianmarco, Verstegen, Monique MA, Francies, Hayley E, Gavarró, Lena Morrill, Bradshaw, Charles R, Allen, George E, Arnes-Benito, Robert, Sidorova, Olga, Gaspersz, Marcia P, Georgakopoulos, Nikitas, Koo, Bon-Kyoung, Dietmann, Sabine, Davies, Susan E, Praseedom, Raaj K, Lieshout, Ruby, IJzermans, Jan N M, Wigmore, Stephen J, Saeb-Parsy, Kourosh, Garnett, Mathew J, van der Laan, Luc JW, Huch, Meritxell

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H3K4 Methylation-Dependent Memory of Somatic Cell Identity Inhibits Reprogramming and Development of Nuclear Transfer Embryos von Hörmanseder, Eva, Simeone, Angela, Allen, George E., Bradshaw, Charles R., Figlmüller, Magdalena, Gurdon, John, Jullien, Jerome

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Mechanical cell competition kills cells via induction of lethal p53 levels von Wagstaff, Laura, Goschorska, Maja, Kozyrska, Kasia, Duclos, Guillaume, Kucinski, Iwo, Chessel, Anatole, Hampton-O’Neil, Lea, Bradshaw, Charles R., Allen, George E., Rawlins, Emma L., Silberzan, Pascal, Carazo Salas, Rafael E., Piddini, Eugenia

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Replication stress induces 53BP1-containing OPT domains in G1 cells von Harrigan, Jeanine A, Belotserkovskaya, Rimma, Coates, Julia, Dimitrova, Daniela S, Polo, Sophie E, Bradshaw, Charles R, Fraser, Peter, Jackson, Stephen P

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Sperm is epigenetically programmed to regulate gene transcription in embryos von Teperek, Marta, Simeone, Angela, Gaggioli, Vincent, Miyamoto, Kei, Allen, George E, Erkek, Serap, Kwon, Taejoon, Marcotte, Edward M, Zegerman, Philip, Bradshaw, Charles R, Peters, Antoine H F M, Gurdon, John B, Jullien, Jerome

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RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state von Belenguer, Germán, Mastrogiovanni, Gianmarco, Pacini, Clare, Hall, Zoe, Dowbaj, Anna M., Arnes-Benito, Robert, Sljukic, Aleksandra, Prior, Nicole, Kakava, Sofia, Bradshaw, Charles R., Davies, Susan, Vacca, Michele, Saeb-Parsy, Kourosh, Koo, Bon-Kyoung, Huch, Meritxell

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Nuclear Wave1 Is Required for Reprogramming Transcription in Oocytes and for Normal Development von Miyamoto, Kei, Teperek, Marta, Yusa, Kosuke, Allen, George E, Bradshaw, Charles R, Gurdon, J. B.

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Downregulation of extraembryonic tension controls body axis formation in avian embryos von Kunz, Daniele, Wang, Anfu, Chan, Chon U, Pritchard, Robyn H., Wang, Wenyu, Gallo, Filomena, Bradshaw, Charles R., Terenzani, Elisa, Müller, Karin H., Huang, Yan Yan Shery, Xiong, Fengzhu

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Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes von Miyamoto, Kei, Nguyen, Khoi T., Allen, George E., Jullien, Jerome, Kumar, Dinesh, Otani, Tomoki, Bradshaw, Charles R., Livesey, Frederick J., Kellis, Manolis, Gurdon, John B.

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Hierarchical Molecular Events Driven by Oocyte-Specific Factors Lead to Rapid and Extensive Reprogramming von Jullien, Jerome, Miyamoto, Kei, Pasque, Vincent, Allen, George E., Bradshaw, Charles R., Garrett, Nigel J., Halley-Stott, Richard P., Kimura, Hiroshi, Ohsumi, Keita, Gurdon, John B.

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Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription von Oikawa, Mami, Simeone, Angela, Hormanseder, Eva, Teperek, Marta, Gaggioli, Vincent, O’Doherty, Alan, Falk, Emma, Sporniak, Matthieu, D’Santos, Clive, Franklin, Valar Nila Roamio, Kishore, Kamal, Bradshaw, Charles R., Keane, Declan, Freour, Thomas, David, Laurent, Grzybowski, Adrian T., Ruthenburg, Alexander J., Gurdon, John, Jullien, Jerome

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Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarity von Winter, Julia Franziska, Höpfner, Sebastian, Korn, Kerstin, Farnung, Benjamin O., Bradshaw, Charles R., Marsico, Giovanni, Volkmer, Michael, Habermann, Bianca, Zerial, Marino

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Small-molecule–induced DNA damage identifies alternative DNA structures in human genes von Rodriguez, Raphaël, Miller, Kyle M, Forment, Josep V, Bradshaw, Charles R, Nikan, Mehran, Britton, Sébastien, Oelschlaegel, Tobias, Xhemalce, Blerta, Balasubramanian, Shankar, Jackson, Stephen P

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CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans von Gaggioli, Vincent, Zeiser, Eva, Rivers, David, Bradshaw, Charles R, Ahringer, Julie, Zegerman, Philip

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Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications von Koziol, Magdalena J, Bradshaw, Charles R, Allen, George E, Costa, Ana S H, Frezza, Christian, Gurdon, John B

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Titration of Four Replication Factors Is Essential for the Xenopus laevis Midblastula Transition von Collart, Clara, Allen, George E., Bradshaw, Charles R., Smith, James C., Zegerman, Philip

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Histone H3 lysine 9 trimethylation is required for suppressing the expression of an embryonically activated retrotransposon in Xenopus laevis von Herberg, Sarah, Simeone, Angela, Oikawa, Mami, Jullien, Jerome, Bradshaw, Charles R, Teperek, Marta, Gurdon, John, Miyamoto, Kei

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REC drives recombination to repair double-strand breaks in animal mtDNA von Klucnika, Anna, Mu, Peiqiang, Jezek, Jan, McCormack, Matthew, Di, Ying, Bradshaw, Charles R, Ma, Hansong

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Small-molecule–induced DNA damage identifies alternative DNA structures in human genes von Rodriguez, Raphaël, Miller, Kyle M, Forment, Josep V, Bradshaw, Charles R, Nikan, Mehran, Britton, Sébastien, Oelschlaegel, Tobias, Xhemalce, Blerta, Balasubramanian, Shankar, Jackson, Stephen P

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