Histamine H3 Receptor as a Drug Discovery Target von Berlin, Michael, Boyce, Christopher W, de Lera Ruiz, Manuel

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Total Syntheses of Ningalin A, Lamellarin O, Lukianol A, and Permethyl Storniamide A Utilizing Heterocyclic Azadiene Diels−Alder Reactions von Boger, Dale L, Boyce, Christopher W, Labroli, Marc A, Sehon, Clark A, Jin, Qing

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Evaluating Spray Drying and Co-Precipitation as Manufacturing Processes for Amorphous Solid Dispersions of a Low Tg API von Solomos, Marina A., Punia, Ashish, Saboo, Sugandha, John, Christopher, Boyce, Christopher W., Chin, Alexander, Taggart, Robert V., Smith, Daniel, Lamm, Matthew S., Schenck, Luke

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Activity of Tricyclic Pyrrolopyrimidine Gyrase B Inhibitor against Mycobacterium abscessus von Madani, Abdeldjalil, Negatu, Dereje A., El Marrouni, Abdellatif, Miller, Randy R., Boyce, Christopher W., Murgolo, Nicholas, Bungard, Christopher J., Zimmerman, Matthew D., Dartois, Véronique, Gengenbacher, Martin, Olsen, David B., Dick, Thomas

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Total Synthesis of Ningalin B Utilizing a Heterocyclic Azadiene Diels−Alder Reaction and Discovery of a New Class of Potent Multidrug Resistant (MDR) Reversal Agents von Boger, Dale L, Soenen, Danielle R, Boyce, Christopher W, Hedrick, Michael P, Jin, Qing

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Pharmacological evaluation of selective α2c-adrenergic agonists in experimental animal models of nasal congestion von Jia, Yanlin, Mingo, Garfield G, Hunter, John C, Lieber, Gissela B, Palamanda, Jairam R, Mei, Hong, Boyce, Christopher W, Koss, Michael C, Yu, Yongxin, Cicmil, Milenko, Hey, John A, McLeod, Robbie L

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CC-1065 and the Duocarmycins:  Synthetic Studies von Boger, Dale L, Boyce, Christopher W, Garbaccio, Robert M, Goldberg, Joel A

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The Invention of WM382, a Highly Potent PMIX/X Dual Inhibitor toward the Treatment of Malaria von de Lera Ruiz, Manuel, Favuzza, Paola, Guo, Zhuyan, Zhao, Lianyun, Hu, Bin, Lei, Zhiyu, Zhan, Dongmei, Murgolo, Nicholas, Boyce, Christopher W., Vavrek, Marissa, Thompson, Jennifer, Ngo, Anna, Jarman, Kate E., Robbins, Johnathan, Boddey, Justin, Sleebs, Brad E., Lowes, Kym N., Cowman, Alan F., Olsen, David B., McCauley, John A.

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Novel Pan-Coronavirus 3CL Protease Inhibitor MK-7845: Biological and Pharmacological Profiling von Alvarez, Nadine, Adam, Gregory C, Howe, John A, Sharma, Vijeta, Zimmerman, Matthew D, Dolgov, Enriko, Rasheed, Risha, Nizar, Fatima, Sahay, Khushboo, Nelson, Andrew M, Park, Steven, Zhou, Xiaoyan, Burlein, Christine, Fay, John F, Iwamoto, Daniel V, Bahnck-Teets, Carolyn M, Getty, Krista L, Lin Goh, Shih, Salhab, Imad, Smith, Keith, Boyce, Christopher W, Cabalu, Tamara D, Murgolo, Nicholas, Fox, Nicholas G, Mayhood, Todd W, Shurtleff, Valerie W, Layton, Mark E, Parish, Craig A, McCauley, John A, Olsen, David B, Perlin, David S

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Selective Metal Cation Activation of a DNA Alkylating Agent:  Synthesis and Evaluation of Methyl 1,2,9,9a-Tetrahydrocyclopropa[c]pyrido[3,2-e]indol-4-one-7-carboxylate (CPyI) von Boger, Dale L, Boyce, Christopher W

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Alpha-2c-Adrenergic Receptors Contribute to Basal Nasal Patency in the Anesthetized Cat von Mingo, Garfield G., Corboz, Michel R., Salisbury, Brian G., McCormick, Kevin D., Boyce, Christopher W., Mukhopadhyay, Gitali, McLeod, Robbie L.

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Recent advances in the development of histamine H3 antagonists von Berlin, Michael, Boyce, Christopher W

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Recent advances in the development of histamine H 3 antagonists von Berlin, Michael, Boyce, Christopher W

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Synthesis and SAR studies of benzimidazolone derivatives as histamine H3-receptor antagonists von Zeng, Qingbei, Rosenblum, Stuart B., Yang, Zhaoxia, Jiang, Yueheng, McCormick, Kevin D., Aslanian, Robert G., Duguma, Luli, Kozlowski, Joseph A., Shih, Neng-Yang, Hey, John A., West, Robert E., Korfmacher, Walter A., Berlin, Michael, Boyce, Christopher W.

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A New Method of in Situ Activation for a Novel Class of DNA Alkylating Agents:  Tunable Metal Cation Complexation and Activation von Boger, Dale L, Wolkenberg, Scott E, Boyce, Christopher W

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Role of α2-adrenoceptors in electrical field stimulation-induced contraction of pig nasal mucosa and pharmacologic characterization of a novel α2C-adrenoceptor agonist von Corboz, Michel R, Rivelli, Maria A, Shah, Himanshu, Boyce, Christopher W, McCormick, Kevin D, Chapman, Richard W, Hunter, John C

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Histamine H 3 Receptor as a Drug Discovery Target von Berlin, Michael, Boyce, Christopher W., de Lera Ruiz, Manuel

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Reduction of hERG inhibitory activity in the 4-piperidinyl urea series of H3 antagonists von Berlin, Michael, Lee, Yoon Joo, Boyce, Christopher W., Wang, Yi, Aslanian, Robert, McCormick, Kevin D., Sorota, Steve, Williams, Shirley M., West, Robert E., Korfmacher, Walter

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Invention of MK-7845, a SARS-CoV‑2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic von Shurtleff, Valerie W., Layton, Mark E., Parish, Craig A., Perkins, James J., Schreier, John D., Wang, Yunyi, Adam, Gregory C., Alvarez, Nadine, Bahmanjah, Soheila, Bahnck-Teets, Carolyn M., Boyce, Christopher W., Burlein, Christine, Cabalu, Tamara D., Campbell, Brian T., Carroll, Steven S., Chang, Wonsuk, de Lera Ruiz, Manuel, Dolgov, Enriko, Fay, John F., Fox, Nicholas G., Goh, Shih Lin, Hartingh, Timothy J., Hurzy, Danielle M., Kelly, Michael J., Klein, Daniel J., Klingler, Franca-Maria, Krishnamurthy, Harini, Kudalkar, Shalley, Mayhood, Todd W., McKenna, Philip M., Murray, Edward M., Nahas, Debbie, Nawrat, Christopher C., Park, Steven, Qian, Dongming, Roecker, Anthony J., Sharma, Vijeta, Shipe, William D., Su, Jing, Taggart, Robert V., Truong, Quang, Wu, Yin, Zhou, Xiaoyan, Zhuang, Ningning, Perlin, David S., Olsen, David B., Howe, John A., McCauley, John A.

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Evaluating Spray Drying and Co-Precipitation as Manufacturing Processes for Amorphous Solid Dispersions of a Low T g API von Solomos, Marina A, Punia, Ashish, Saboo, Sugandha, John, Christopher, Boyce, Christopher W, Chin, Alexander, Taggart, Robert V, Smith, Daniel, Lamm, Matthew S, Schenck, Luke

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