HLA-B27 von Bowness, Paul

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New developments in our understanding of ankylosing spondylitis pathogenesis von Voruganti, Aniruddha, Bowness, Paul

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CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses von Hammitzsch, Ariane, Tallant, Cynthia, Fedorov, Oleg, O’Mahony, Alison, Brennan, Paul E., Hay, Duncan A., Martinez, Fernando O., Al-Mossawi, M. Hussein, de Wit, Jelle, Vecellio, Matteo, Wells, Christopher, Wordsworth, Paul, Müller, Susanne, Knapp, Stefan, Bowness, Paul

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Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis von Penkava, Frank, Velasco-Herrera, Martin Del Castillo, Young, Matthew D., Yager, Nicole, Nwosu, Lilian N., Pratt, Arthur G., Lara, Alicia Lledo, Guzzo, Charlotte, Maroof, Ash, Mamanova, Lira, Cole, Suzanne, Efremova, Mirjana, Simone, Davide, Filer, Andrew, Brown, Chrysothemis C., Croxford, Andrew L., Isaacs, John D., Teichmann, Sarah, Bowness, Paul, Behjati, Sam, Hussein Al-Mossawi, M.

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A genetics-led approach defines the drug target landscape of 30 immune-related traits von Fang, Hai, De Wolf, Hans, Knezevic, Bogdan, Burnham, Katie L., Osgood, Julie, Sanniti, Anna, Lledó Lara, Alicia, Kasela, Silva, De Cesco, Stephane, Wegner, Jörg K., Handunnetthi, Lahiru, McCann, Fiona E., Chen, Liye, Sekine, Takuya, Brennan, Paul E., Marsden, Brian D., Damerell, David, O’Callaghan, Chris A., Bountra, Chas, Bowness, Paul, Sundström, Yvonne, Milani, Lili, Berg, Louise, Göhlmann, Hinrich W., Peeters, Pieter J., Fairfax, Benjamin P., Sundström, Michael, Knight, Julian C.

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From the Genetics of Ankylosing Spondylitis to New Biology and Drug Target Discovery von Nancy, Zaarour, Yan, Li, Hui, Shi, Paul, Bowness, Liye, Chen

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Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism von Cribbs, Adam P., Terlecki-Zaniewicz, Stefan, Philpott, Martin, Baardman, Jeroen, Ahern, David, Lindow, Morten, Obad, Susanna, Oerum, Henrik, Sampey, Brante, Mander, Palwinder K., Penn, Henry, Wordsworth, Paul, Bowness, Paul, de Winther, Menno, Prinjha, Rab K., Feldmann, Marc, Oppermann, Udo

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A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis von Schwerd, Tobias, Twigg, Stephen R F, Aschenbrenner, Dominik, Manrique, Santiago, Miller, Kerry A, Taylor, Indira B, Capitani, Melania, McGowan, Simon J, Sweeney, Elizabeth, Weber, Astrid, Chen, Liye, Bowness, Paul, Riordan, Andrew, Cant, Andrew, Freeman, Alexandra F, Milner, Joshua D, Holland, Steven M, Frede, Natalie, Müller, Miryam, Schmidt-Arras, Dirk, Grimbacher, Bodo, Wall, Steven A, Jones, E Yvonne, Wilkie, Andrew O M, Uhlig, Holm H

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Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis von Bowness, Paul, Ridley, Anna, Shaw, Jacqueline, Chan, Antoni T, Wong-Baeza, Isabel, Fleming, Myles, Cummings, Fraser, McMichael, Andrew, Kollnberger, Simon

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Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming von Kochan, Grazyna, Krojer, Tobias, Harvey, David, Fischer, Roman, Chen, Liye, Vollmar, Melanie, von Delft, Frank, Kavanagh, Kathryn L, Brown, Matthew A, Bowness, Paul, Wordsworth, Paul, Kessler, Benedikt M, Oppermann, Udo

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Progress in our understanding of the pathogenesis of ankylosing spondylitis von Simone, Davide, Al Mossawi, M Hussein, Bowness, Paul

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Analysis of CD161 expression on human CD8⁺ T cells defines a distinct functional subset with tissue-homing properties von Billerbeck, Eva, Kang, Yu-Hoi, Walker, Lucy, Lockstone, Helen, Grafmueller, Stefanie, Fleming, Vicki, Flint, Jonathan, Willberg, Chris B, Bengsch, Bertram, Seigel, Bianca, Ramamurthy, Narayan, Zitzmann, Nicole, Barnes, Eleanor J, Thevanayagam, Jonarthan, Bhagwanani, Anisha, Leslie, Alasdair, Oo, Ye H, Kollnberger, Simon, Bowness, Paul, Drognitz, Oliver, Adams, David H, Blum, Hubert E, Thimme, Robert, Klenerman, Paul

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Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele von Al-Mossawi, Hussein, Yager, Nicole, Taylor, Chelsea A., Lau, Evelyn, Danielli, Sara, de Wit, Jelle, Gilchrist, James, Nassiri, Isar, Mahe, Elise A., Lee, Wanseon, Rizvi, Laila, Makino, Seiko, Cheeseman, Jane, Neville, Matt, Knight, Julian C., Bowness, Paul, Fairfax, Benjamin P.

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Critical Role of Endoplasmic Reticulum Aminopeptidase 1 in Determining the Length and Sequence of Peptides Bound and Presented by HLA–B27 von Chen, Liye, Fischer, Roman, Peng, Yanchun, Reeves, Emma, McHugh, Kirsty, Ternette, Nicola, Hanke, Tomas, Dong, Tao, Elliott, Tim, Shastri, Nilabh, Kollnberger, Simon, James, Edward, Kessler, Benedikt, Bowness, Paul

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GM-CSF Primes Proinflammatory Monocyte Responses in Ankylosing Spondylitis von Shi, Hui, Chen, Liye, Ridley, Anna, Zaarour, Nancy, Brough, India, Caucci, Cherilyn, Smith, Julia E, Bowness, Paul

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Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates von Simone, Davide, Penkava, Frank, Ridley, Anna, Sansom, Stephen, Al-Mossawi, M. Hussein, Bowness, Paul

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Increased interleukin-26 in the peripheral joints of patients with axial spondyloarthritis and psoriatic arthritis, co-localizing with CD68-positive synoviocytes von Hammitzsch, Ariane, Ossadnik, Andreas, Bachmann, Quirin, Merwald-Fraenk, Helga, Lorenz, Georg, Witt, Matthias, Wiesent, Franziska, Mühlhofer, Heinrich, Simone, Davide, Bowness, Paul, Heemann, Uwe, Arbogast, Martin, Moog, Philipp, Schmaderer, Christoph

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I130 New developments in the pathogenesis of SpA von Bowness, Paul

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I086 Introduction to single cell analyses and rheumatic disease von Bowness, Paul

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Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators von Lagou, Vasiliki, Garcia-Perez, Josselyn E., Smets, Ide, Van Horebeek, Lies, Vandebergh, Marijne, Chen, Liye, Mallants, Klara, Prezzemolo, Teresa, Hilven, Kelly, Humblet-Baron, Stephanie, Moisse, Matthieu, Van Damme, Philip, Boeckxstaens, Guy, Bowness, Paul, Dubois, Bénédicte, Dooley, James, Liston, Adrian, Goris, An

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