Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation von Seidah, Nabil G, Poirier, Steve, Denis, Maxime, Parker, Rex, Miao, Bowman, Mapelli, Claudio, Prat, Annik, Wassef, Hanny, Davignon, Jean, Hajjar, Katherine A, Mayer, Gaétan

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Pharmacologic profile of the Adnectin BMS-962476, a small protein biologic alternative to PCSK9 antibodies for low-density lipoprotein lowering von Mitchell, Tracy, Chao, Ginger, Sitkoff, Doree, Lo, Fred, Monshizadegan, Hossain, Meyers, Daniel, Low, Simon, Russo, Katie, DiBella, Rose, Denhez, Fabienne, Gao, Mian, Myers, Joseph, Duke, Gerald, Witmer, Mark, Miao, Bowman, Ho, Siew P, Khan, Javed, Parker, Rex A

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Raising HDL cholesterol without inducing hepatic steatosis and hypertriglyceridemia by a selective LXR modulator von Miao, Bowman, Zondlo, Susan, Gibbs, Sandy, Cromley, Debra, Hosagrahara, Vinayak P., Kirchgessner, Todd G., Billheimer, Jeffrey, Mukherjee, Ranjan

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Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters von Huber, Reid M, Murphy, Kathleen, Miao, Bowman, Link, John R, Cunningham, Mark R, Rupar, Mark J, Gunyuzlu, Paul L, Haws, Thomas F, Kassam, Altaf, Powell, Francoise, Hollis, Gregory F, Young, Peter R, Mukherjee, Ranjan, Burn, Timothy C

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Retinoid X Receptor (RXR) Agonist-induced Antagonism of Farnesoid X Receptor (FXR) Activity due to Absence of Coactivator Recruitment and Decreased DNA Binding von Kassam, Altaf, Miao, Bowman, Young, Peter R, Mukherjee, Ranjan

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Synthesis and structure–activity relationships of 2-aryl-4-oxazolylmethoxy benzylglycines and 2-aryl-4-thiazolylmethoxy benzylglycines as novel, potent PPARα selective activators-... von Ye, Xiang-Yang, Chen, Stephanie, Zhang, Hao, Locke, Kenneth T., O’Malley, Kevin, Zhang, Litao, Srivastava, Raijit, Miao, Bowman, Meyers, Daniel, Monshizadegan, Hossain, Search, Debra, Grimm, Denise, Zhang, Rongan, Lippy, Jonathan, Twamley, Celeste, Muckelbauer, Jodi K., Chang, Chiehying, An, Yongmi, Hosagrahara, Vinayak, Zhang, Lisa, Yang, T.-J., Mukherjee, Ranjan, Cheng, Peter T.W., Tino, Joseph A.

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Effects of the Prosegment and pH on the Activity of PCSK9: EVIDENCE FOR ADDITIONAL PROCESSING EVENTS von Benjannet, Suzanne, Luna Saavedra, Yascara Grisel, Hamelin, Josée, Asselin, Marie-Claude, Essalmani, Rachid, Pasquato, Antonella, Lemaire, Peter, Duke, Gerald, Miao, Bowman, Duclos, Franck, Parker, Rex, Mayer, Gaétan, Seidah, Nabil G

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Discovery of an Oxybenzylglycine Based Peroxisome Proliferator Activated Receptor α Selective Agonist 2-((3-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl... von Li, Jun, Kennedy, Lawrence J, Shi, Yan, Tao, Shiwei, Ye, Xiang-Yang, Chen, Stephanie Y, Wang, Ying, Hernández, Andrés S, Wang, Wei, Devasthale, Pratik V, Chen, Sean, Lai, Zhi, Zhang, Hao, Wu, Shung, Smirk, Rebecca A, Bolton, Scott A, Ryono, Denis E, Zhang, Huiping, Lim, Ngiap-Kie, Chen, Bang-Chi, Locke, Kenneth T, O’Malley, Kevin M, Zhang, Litao, Srivastava, Rai Ajit, Miao, Bowman, Meyers, Daniel S, Monshizadegan, Hossain, Search, Debra, Grimm, Denise, Zhang, Rongan, Harrity, Thomas, Kunselman, Lori K, Cap, Michael, Kadiyala, Pathanjali, Hosagrahara, Vinayak, Zhang, Lisa, Xu, Carrie, Li, Yi-Xin, Muckelbauer, Jodi K, Chang, Chiehying, An, Yongmi, Krystek, Stanley R, Blanar, Michael A, Zahler, Robert, Mukherjee, Ranjan, Cheng, Peter T. W, Tino, Joseph A

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Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARα Selective Agonist von Shi, Yan, Li, Jun, Kennedy, Lawrence J, Tao, Shiwei, Hernández, Andrés S, Lai, Zhi, Chen, Sean, Wong, Henry, Zhu, Juliang, Trehan, Ashok, Lim, Ngiap-Kie, Zhang, Huiping, Chen, Bang-Chi, Locke, Kenneth T, O’Malley, Kevin M, Zhang, Litao, Srivastava, Rai Ajit, Miao, Bowman, Meyers, Daniel S, Monshizadegan, Hossain, Search, Debra, Grimm, Denise, Zhang, Rongan, Harrity, Thomas, Kunselman, Lori K, Cap, Michael, Muckelbauer, Jodi, Chang, Chiehying, Krystek, Stanley R, Li, Yi-Xin, Hosagrahara, Vinayak, Zhang, Lisa, Kadiyala, Pathanjali, Xu, Carrie, Blanar, Michael A, Zahler, Robert, Mukherjee, Ranjan, Cheng, Peter T. W, Tino, Joseph A

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Effects of the Prosegment and pH on the Activity of PCSK9 von Benjannet, Suzanne, Luna Saavedra, Yascara Grisel, Hamelin, Josée, Asselin, Marie-Claude, Essalmani, Rachid, Pasquato, Antonella, Lemaire, Peter, Duke, Gerald, Miao, Bowman, Duclos, Franck, Parker, Rex, Mayer, Gaétan, Seidah, Nabil G.

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Discovery of an Oxybenzylglycine Based Peroxisome Proliferator Activated Receptor [alpha] Selective Agonist 2-((3-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxyca... von Li, Jun, Kennedy, Lawrence J., Shi, Yan, Tao, Shiwei, Ye, Xiang-Yang, Chen, Stephanie Y., Wang, Ying, Hernndez, Andrs S., Wang, Wei, Devasthale, Pratik V., Chen, Sean, Lai, Zhi, Zhang, Hao, Wu, Shung, Smirk, Rebecca A., Bolton, Scott A., Ryono, Denis E., Zhang, Huiping, Lim, Ngiap-Kie, Chen, Bang-Chi, Locke, Kenneth T., O’Malley, Kevin M., Zhang, Litao, Srivastava, Rai Ajit, Miao, Bowman, Meyers, Daniel S., Monshizadegan, Hossain, Search, Debra, Grimm, Denise, Zhang, Rongan, Harrity, Thomas, Kunselman, Lori K., Cap, Michael, Kadiyala, Pathanjali, Hosagrahara, Vinayak, Zhang, Lisa, Xu, Carrie, Li, Yi-Xin, Muckelbauer, Jodi K., Chang, Chiehying, An, Yongmi, Krystek, Stanley R., Blanar, Michael A., Zahler, Robert, Mukherjee, Ranjan, Cheng, Peter T.W., Tino, Joseph A.

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Ligand and coactivator recruitment preferences of peroxisome proliferator activated receptor α von Mukherjee, Ranjan, Sun, Shaoxian, Santomenna, Linda, Miao, Bowman, Walton, Harry, Liao, Boshan, Locke, Kenneth, Zhang, Ji-Hu, Nguyen, Sonny H., Zhang, Li Tao, Murphy, Kathleen, Ross, Harold O, Xia, M.X., Teleha, Christopher, Chen, S.-Y., Selling, Bernard, Wynn, Richard, Burn, Timothy, Young, Peter R.

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FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND PCSK9 von Mitchell, Tracy S, Sitkoff, Doree F, Rakestraw, Ginger C, Lo, Ching-Hsiung Frederick, Parker, Rex A, Davis, Jonathan H, Denhez, Fabienne M, Miao, Bowman, Russo, Katie A, CAMPHAUSEN, Ray, Low, Chee Meng, Cload, Sharon T, Lipovsek, Dasa, Saeed-Kothe, Amna

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Fibronectin based scaffold domain proteins that bind PCSK9 von Mitchell, Tracy S, Sitkoff, Doree F, Rakestraw, Ginger C, Lo, Ching-Hsiung Frederick, Parker, Rex A, Camphausen, Ray, Davis, Jonathan H, Denhez, Fabienne M, Miao, Bowman, Russo, Katie A, Low, Chee Meng, Cload, Sharon T, Lipovsek, Dasa, Saeed-Kothe, Amna

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Synthesis and structure-activity relationships of 2-aryl-4-oxazolylmethoxy benzylglycines and 2-aryl-4-thiazolylmethoxy benzylglycines as novel, potent PPARalpha selective activato... von Ye, Xiang-Yang, Chen, Stephanie, Zhang, Hao, Locke, Kenneth T, O'Malley, Kevin, Zhang, Litao, Srivastava, Raijit, Miao, Bowman, Meyers, Daniel, Monshizadegan, Hossain, Search, Debra, Grimm, Denise, Zhang, Rongan, Lippy, Jonathan, Twamley, Celeste, Muckelbauer, Jodi K, Chang, Chiehying, An, Yongmi, Hosagrahara, Vinayak, Zhang, Lisa, Yang, T-J, Mukherjee, Ranjan, Cheng, Peter T W, Tino, Joseph A

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Ligand-induced coactivator recruitment to peroxisome proliferator-activated receptorα characterized by fluorescence resonance energy transfer von Miao, Bowman, Sun, Shaoxian, Santomenna, Linda D., Zhang, Ji Hu, Young, Peter, Mukherjee, Ranjan

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ANTIBODIES THAT BIND NOVEL PCSK9 VARIANTS von Miao, Bowman, Chen, Jian, Parker, Rex Arnold, Mintier, Gabriel A, Feder, John N

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Fibronectin based scaffold domain proteins that bind PCSK9 von Mitchell, Tracy S, Sitkoff, Doree F, Rakestraw, Ginger C, Lo, Ching-Hsiung Frederick, Parker, Rex A, Camphausen, Ray, Davis, Jonathan H, Denhez, Fabienne M, Miao, Bowman, Russo, Katie A, Low, Chee Meng, Cload, Sharon T, Lipovsek, Dasa, Saeed-Kothe, Amna

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FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND PCSK9 von LIPOVSEK, Dasa, MIAO, Bowman, LOW, Chee Meng, RAKESTRAW, Ginger C, SITKOFF, Doree F, LO, Ching-Hsiung Frederick, DENHEZ, Fabienne M, DAVIS, Jonathan H, SAEED-KOTHE, Amna, RUSSO, Katie A, CAMPHAUSEN, Ray, MITCHELL, Tracy S, CLOAD, Sharon T, PARKER, Rex A

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ANTIBODIES THAT BIND NOVEL PCSK9 VARIANTS von MINTIER Gabriel A, Chen Jian, Miao Bowman, Feder John N, Parker Rex Arnold

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