Evaluation of crizotinib absolute bioavailability, the bioequivalence of three oral formulations, and the effect of food on crizotinib pharmacokinetics in healthy subjects von Xu, Huiping, O'Gorman, Melissa, Boutros, Tanya, Brega, Nicoletta, Kantaridis, Constantino, Tan, Weiwei, Bello, Akintunde

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Evaluation of Proton Pump Inhibitor Esomeprazole on Crizotinib Pharmacokinetics in Healthy Participants von Xu, Huiping, O'Gorman, Melissa, Matschke, Kyle, Boutros, Tanya, Brega, Nicoletta, Tan, Weiwei, Bello, Akintunde

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Abstract CT208: Absolute bioavailability of dacomitinib (PF-00299804): Comparison of oral and intravenous administration in healthy volunteers von Giri, Nagdeep, LaBadie, Robert R., Liang, Yali, Boutros, Tanya, Goldberg, Zelanna, Bello, Carlo L.

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Investigation of the impact of hepatic impairment on the pharmacokinetics of dacomitinib von Giri, Nagdeep, Masters, Joanna C., Plotka, Anna, Liang, Yali, Boutros, Tanya, Pardo, Patricia, O’Connell, Joseph, Bello, Carlo

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Effects of Renal Function on Crizotinib Pharmacokinetics: Dose Recommendations for Patients with ALK-Positive Non-Small Cell Lung Cancer von Tan, Weiwei, Yamazaki, Shinji, Johnson, Theodore R., Wang, Rong, O’Gorman, Melissa T., Kirkovsky, Leonid, Boutros, Tanya, Brega, Nicoletta M., Bello, Akintunde

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Abstract LB-229: A phase 1 open-label fixed-sequence two-period crossover study of the effect of multiple doses of tamoxifen on palbociclib (PD-0332991) pharmacokinetics in healthy... von Hoffman, Justin T., O'Gorman, Melissa, Loi, Cho-Ming, Plotka, Anna, Boutros, Tanya, Kirkovsky, Leonid, Stampino, Corrado Gallo, Wang, Diane

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Effect of food or proton pump inhibitor treatment on the bioavailability of dacomitinib in healthy volunteers von Ruiz-Garcia, Ana, Masters, Joanna C., Mendes da Costa, Laure, LaBadie, Robert R., Liang, Yali, Ni, Grace, Ellery, Craig A., Boutros, Tanya, Goldberg, Zelanna, Bello, Carlo L.

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A phase I open-label study to investigate the potential drug-drug interaction between single-dose dacomitinib and steady-state paroxetine in healthy volunteers von Ruiz-Garcia, Ana, Giri, Nagdeep, LaBadie, Robert R., Ni, Grace, Boutros, Tanya, Richie, Nicole, Kocinsky, Hetal S., Checchio, Tina M., Bello, Carlo L.

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Influence of mild and moderate hepatic impairment on the pharmacokinetics (PK) of the pan-HER inhibitor dacomitinib von Giri, Nagdeep, Plotka, Anna, Liang, Yali, Boutros, Tanya, Ni, Grace, Masters, Joanna, DeMicco, Michael, Pardo, Patricia, Bello, Carlo, O'Connell, Joseph

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The effect of dacomitinib (PF-00299804) on CYP2D6 activity in healthy volunteers who are extensive or intermediate metabolizers von Bello, Carlo L., LaBadie, Robert R., Ni, Grace, Boutros, Tanya, McCormick, Carol, Ndongo, M. Noella

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A phase I open-label study to investigate the potential drug-drug interaction between single-dose dacomitinib and steady-state paroxetine in healthy volunteers: The Journal of Clin... von Ruiz-Garcia, Ana, Giri, Nagdeep, LaBadie, Robert R., Ni, Grace, Boutros, Tanya, Richie, Nicole, Kocinsky, Hetal S., Checchio, Tina M., Bello, Carlo L.

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Abstract 763: A phase 1 open-label study to investigate the potential drug-drug interaction (DDI) between single-dose (SD) dacomitinib (PF-00299804; DC) and steady-state (SS) parox... von RuizαGarcia, Ana, Giri, Nagdeep, LaBadie, Robert R., Ni, Grace, Boutros, Tanya, Richie, Nicole, Kocinsky, Hetal S., Bello, Carlo L.

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Photolithography of self-assembled monolayers: optimization of protecting groups by an electroanalytical method von Jennane, Jamila, Boutros, Tanya, Giasson, Richard

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Pharmacodynamic interaction between ezetimibe and rosuvastatin von Kosoglou, Teddy, Statkevich, Paul, Yang, Bo, Suresh, Ramachandran, Zhu, Yali, Boutros, Tanya, Maxwell, Stephen E., Tiessen, Renger, Cutler, David L.

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Pharmacokinetic interaction between ezetimibe and lovastatin in healthy volunteers von Reyderman, Larisa, Kosoglou, Teddy, Boutros, Tanya, Seiberling, Michael, Statkevich, Paul

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Effect of race and sex on single and multiple dose pharmacokinetics of desloratadine von Affrime, Melton, Banfield, Christopher, Gupta, Samir, Cohen, Albert, Boutros, Tanya, Thonoor, Mohan, Cayen, Mitchell

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Effect of race and sex on single and multiple dose pharmacokinetics of desloratadine: Desloratadine: Clinical Pharmacokinetics of a Novel H1 Receptor Antagonist von AFFRIME, Melton, BANFIELD, Christopher, GUPTA, Samir, COHEN, Albert, BOUTROS, Tanya, THONOOR, Mohan, CAYEN, Mitchell

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A three‐gene DNA methylation biomarker accurately classifies early stage prostate cancer von Patel, Palak G., Wessel, Thomas, Kawashima, Atsunari, Okello, John B. A., Jamaspishvili, Tamara, Guérard, Karl‐Philippe, Lee, Laura, Lee, Anna Ying‐Wah, How, Nathan E., Dion, Dan, Scarlata, Eleonora, Jackson, Chelsea L., Boursalie, Suzanne, Sack, Tanya, Dunn, Rachel, Moussa, Madeleine, Mackie/, Karen, Ellis, Audrey, Marra, Elizabeth, Chin, Joseph, Siddiqui, Khurram, Hetou, Khalil, Pickard, Lee‐Anne, Arthur‐Hayward, Vinolia, Bauman, Glenn, Chevalier, Simone, Brimo, Fadi, Boutros, Paul C., Lapointe PhD, Jacques, Bartlett, John M. S., Gooding, Robert J., Berman, David M.

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In vitro efficacy of a copper iodine complex PPE disinfectant for SARS-CoV-2 inactivation [version 2; peer review: 2 approved] von Mantlo, Emily, Rhodes, Tanya, Boutros, Jenny, Patterson-Fortin, Laura, Evans, Alex, Paessler, Slobodan

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In vitro efficacy of a copper iodine complex PPE disinfectant for SARS-CoV-2 inactivation [version 1; peer review: 1 approved, 1 approved with reservations] von Mantlo, Emily, Rhodes, Tanya, Boutros, Jenny, Patterson-Fortin, Laura, Evans, Alex, Paessler, Slobodan

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