Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia von Dafflon, C, Craig, V J, Méreau, H, Gräsel, J, Schacher Engstler, B, Hoffman, G, Nigsch, F, Gaulis, S, Barys, L, Ito, M, Aguadé-Gorgorió, J, Bornhauser, B, Bourquin, J-P, Proske, A, Stork-Fux, C, Murakami, M, Sellers, W R, Hofmann, F, Schwaller, J, Tiedt, R

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A revolutionary graphitisation system: Fully automated, compact and simple von Wacker, L., Němec, M., Bourquin, J.

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An international study of intrachromosomal amplification of chromosome 21 (iAMP21): cytogenetic characterization and outcome von Harrison, C J, Moorman, A V, Schwab, C, Carroll, A J, Raetz, E A, Devidas, M, Strehl, S, Nebral, K, Harbott, J, Teigler-Schlegel, A, Zimmerman, M, Dastuge, N, Baruchel, A, Soulier, J, Auclerc, M-F, Attarbaschi, A, Mann, G, Stark, B, Cazzaniga, G, Chilton, L, Vandenberghe, P, Forestier, E, Haltrich, I, Raimondi, S C, Parihar, M, Bourquin, J-P, Tchinda, J, Haferlach, C, Vora, A, Hunger, S P, Heerema, N A, Haas, O A

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Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy von Stankov, M V, El Khatib, M, Kumar Thakur, B, Heitmann, K, Panayotova-Dimitrova, D, Schoening, J, Bourquin, J P, Schweitzer, N, Leverkus, M, Welte, K, Reinhardt, D, Li, Z, Orkin, S H, Behrens, G M N, Klusmann, J H

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Monitoring minimal residual disease in children with high-risk relapses of acute lymphoblastic leukemia: prognostic relevance of early and late assessment von Eckert, C, Hagedorn, N, Sramkova, L, Mann, G, Panzer-Grümayer, R, Peters, C, Bourquin, J-P, Klingebiel, T, Borkhardt, A, Cario, G, Alten, J, Escherich, G, Astrahantseff, K, Seeger, K, Henze, G, von Stackelberg, A

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Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia von Peirs, S, Frismantas, V, Matthijssens, F, Van Loocke, W, Pieters, T, Vandamme, N, Lintermans, B, Dobay, M P, Berx, G, Poppe, B, Goossens, S, Bornhauser, B C, Bourquin, J-P, Van Vlierberghe, P

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Favorable outcome in infants with AML after intensive first- and second-line treatment: an AML-BFM study group report von Creutzig, U, Zimmermann, M, Bourquin, J-P, Dworzak, M N, Kremens, B, Lehrnbecher, T, von Neuhoff, C, Sander, A, von Stackelberg, A, Schmid, I, Starý, J, Steinbach, D, Vormoor, J, Reinhardt, D

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Pharmacological activity of CB-103: An oral pan-NOTCH inhibitor targeting the NOTCH transcription complex von Weber, D., Lehal, R., Frismantas, V., Bourquin, J.-P., Bauer, M., Murone, M., Radtke, F.

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Longitudinal lung function in childhood cancer survivors after hematopoietic stem cell transplantation von Otth, Maria, Yammine, Sophie, Usemann, Jakob, Latzin, Philipp, Mader, Luzius, Spycher, Ben, Güngör, Tayfun, Scheinemann, Katrin, Kuehni, Claudia E.

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P319: THE TESTICULAR NICHE OF ACUTE LYMPHOBLASTIC LEUKEMIA – MOLECULAR AND CELLULAR FACTORS FOR THE PREFERENTIAL MIGRATION AND SURVIVAL von Skroblyn, T., Joedicke, J. J., Pfau, M., Krüger, K., Bourquin, J.‐P., Izraeli, S., Eckert, C., Höpken, U. E.

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Correction: CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC von Tirado-Gonzalez, I., Czlonka, E., Nevmerzhitskaya, A., Soetopo, D., Bergonzani, E., Mahmoud, A., Contreras, A., Jeremias, I., Platzbecker, U., Bourquin, J. P., Kloz, U., Van der Hoeven, F., Medyouf, H.

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A novel sample holder for 4D live cell imaging to study cellular dynamics in complex 3D tissue cultures von Septiadi, D., Bourquin, J., Durantie, E., Petri-Fink, A., Rothen-Rutishauser, B.

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CD2-positive B-cell precursor acute lymphoblastic leukemia with an early switch to the monocytic lineage von Slamova, L, Starkova, J, Fronkova, E, Zaliova, M, Reznickova, L, van Delft, F W, Vodickova, E, Volejnikova, J, Zemanova, Z, Polgarova, K, Cario, G, Figueroa, M, Kalina, T, Fiser, K, Bourquin, J P, Bornhauser, B, Dworzak, M, Zuna, J, Trka, J, Stary, J, Hrusak, O, Mejstrikova, E

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Transplant characteristics and self-reported pulmonary outcomes in Swiss childhood cancer survivors after hematopoietic stem cell transplantation—a cohort study von Otth, Maria, Schindera, Christina, Güngör, Tayfun, Ansari, Marc, Scheinemann, Katrin, Belle, Fabiën N., Latzin, Philipp, von der Weid, Nicolas, Kuehni, Claudia E.

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Additional treatment with 2-Chloro-2-Deoxyadenosine during consolidation in children with high-risk acute myeloid leukemia does not improve survival von Creutzig, U, Dworzak, M N, Zimmermann, M, Bourquin, J-P, Gruhn, B, Fleischhack, G, Graf, N, Klingebiel, T, Kremens, B, Lehrnbecher, T, von Neuhoff, C, Stackelberg, A v, Starý, J, Reinhardt, D

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RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo von Jyotsana, N, Sharma, A, Chaturvedi, A, Scherr, M, Kuchenbauer, F, Sajti, L, Barchanski, A, Lindner, R, Noyan, F, Sühs, K-W, Grote-Koska, D, Brand, K, Vornlocher, H-P, Stanulla, M, Bornhauser, B, Bourquin, J-P, Eder, M, Thol, F, Ganser, A, Humphries, R K, Ramsay, E, Cullis, P, Heuser, M

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CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC von Tirado-Gonzalez, I, Czlonka, E, Nevmerzhitskaya, A, Soetopo, D, Bergonzani, E, Mahmoud, A, Contreras, A, Jeremias, I, Platzbecker, U, Bourquin, J P, Kloz, U, Van der Hoeven, F, Medyouf, H

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Genotype-outcome correlations in pediatric AML: the impact of a monosomal karyotype in trial AML-BFM 2004 von Rasche, M, von Neuhoff, C, Dworzak, M, Bourquin, J-P, Bradtke, J, Göhring, G, Escherich, G, Fleischhack, G, Graf, N, Gruhn, B, Haas, O A, Klingebiel, T, Kremens, B, Lehrnbecher, T, von Stackelberg, A, Tchinda, J, Zemanova, Z, Thiede, C, von Neuhoff, N, Zimmermann, M, Creutzig, U, Reinhardt, D

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S107: SOD2 PROMOTES ACUTE LEUKEMIA ADAPTATION TO AMINO ACID STARVATION THROUGH THE N‐DEGRON PATHWAY von Ibrahim, N. K., Schreek, S., Cinar, B., Loxha, L., Fehlhaber, B., Bourquin, J.‐P., Bornhauser, B., Eckert, C., Cario, G., Forster, M., Stanulla, M., Gutierrez, A., Hinze, L.

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S108: PEDIATRIC T‐ ALL RELAPSE: CONSTITUTIONAL CANCER PREDISPOSITION AND HYPERMUTATATOR PHENOTYPES von Richter‐Pechanska, P., Kunz, J., Rausch, T., Erarslan‐Uysal, B., Bornhauser, B., Frismantas, V., Assenov, Y., Zimmermann, M., Happich, M., Knebel‐Doeberitz, C., Neuhoff, N., Koehler, R., Stanulla, M., Schrappe, M., Cario, G., Escherich, G., Kischner‐Schwabe, R., Eckert, C., Avigad, S., Pfister, S., Muckenthaler, M., Bourquin, J.‐P., Korbel, J., Kulozik, A.

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