Intrahepatic and Peripheral CXCL10 Expression in Hepatitis C Virus-Infected Patients Treated With Telaprevir, Pegylated Interferon, and Ribavirin von Zeremski, Marija, Dimova, Rositsa B., Benjamin, Samantha, Penney, Marina S., Botfield, Martyn C., Talal, Andrew H.

Volltext

Telaprevir‐based treatment effects on hepatitis C virus in liver and blood von Talal, Andrew H., Dimova, Rositsa B., Zhang, Eileen Z., Jiang, Min, Penney, Marina S., Sullivan, James C., Botfield, Martyn C., Chakilam, Ananthsrinivas, Sawant, Rishikesh, Cervini, Christine M., Zeremski, Marija, Jacobson, Ira M., Kwong, Ann D.

Volltext

Hyperpolarized helium-3 magnetic resonance lung imaging of non-sedated infants and young children: a proof-of-concept study von Altes, Talissa A, Meyer, Craig H, Mata, Jaime F, Froh, Deborah K, Paget-Brown, Alix, Gerald Teague, W, Fain, Sean B, de Lange, Eduard E, Ruppert, Kai, Botfield, Martyn C, Johnson, Mac A, Mugler, John P

Volltext

Assessment of Repeatability of Hyperpolarized Gas MR Ventilation Functional Imaging in Cystic Fibrosis von O’Sullivan, Brian, MD, Couch, Marcus, MSc, Roche, John P., PhD, Walvick, Ronn, PhD, Zheng, Shaokuan, PhD, Baker, Dawn, ARNP, Johnson, Mac, PhD, Botfield, Martyn, PhD, Albert, Mitchell S., PhD

Volltext

Active-Site Residues of Escherichia coli DNA Gyrase Required in Coupling ATP Hydrolysis to DNA Supercoiling and Amino Acid Substitutions Leading to Novobiocin Resistance von GROSS, Christian H, PARSONS, Jonathan D, RAYBUCK, Scott A, GROSSMAN, Trudy H, CHARIFSON, Paul S, BELLON, Steven, JERNEE, James, DWYER, Maureen, CHAMBERS, Stephen P, MARKLAND, William, BOTFIELD, Martyn

Volltext

Tandem SH2 Domains Confer High Specificity in Tyrosine Kinase Signaling von Ottinger, Elizabeth A., Botfield, Martyn C., Shoelson, Steven E.

Volltext

TELAPREVIR-BASED REGIMENS SUBSTANTIALLY IMPROVED SVR RATES ACROSS ALL IL28B GENOTYPES IN THE ADVANCE TRIAL von Jacobson, Ira M, Catlett, Ian M, Marcellin, Patrick, Bzowej, Natalie H, Muir, Andrew J, Adda, Nathalie, Seepersaud, Shelia, Ramachandran, Ravi, Sussky, Katherine, Bengtsson, Leif, George, Shelley, Kauffman, Robert S, Botfield, Martyn C

Volltext

Similar SVR Rates in IL28B CC, CT or TT Prior Relapser, Partial- or Null-Responder Patients Treated With Telaprevir/Peginterferon/Ribavirin: Retrospective Analysis of the Realize S... von Younossi, Zobair M, Aerssens, Jeroen, Pol, Stanislas, Pockros, Paul, Lawitz, Eric J, Zeuzem, Stefan, Andreone, Pietro, Roberts, Stuart K, Foster, Graham, Focaccia, Roberto, Horban, Andrzej, van Heeswijk, Rolf, De Meyer, Sandra, Luo, Don, Botfield, Martyn C, Beumont-Mauviel, Maria, Picchio, Gaston

Volltext

A signature for immune response correlates with HCV treatment outcome in Caucasian subjects von Hare, Brian J., Haseltine, Eric, Fleming, Mark, Chelsky, Daniel, McIntosh, Laura, Allard, Rene, Botfield, Martyn

Volltext

Discovery of Potent and Selective SH2 Inhibitors of the Tyrosine Kinase ZAP-70 von Vu, Chi B, Corpuz, Evelyn G, Merry, Taylor J, Pradeepan, Selvaluxmi G, Bartlett, Catherine, Bohacek, Regine S, Botfield, Martyn C, Eyermann, Charles J, Lynch, Berkley A, MacNeil, Ian A, Ram, Mary K, van Schravendijk, Marie Rose, Violette, Shelia, Sawyer, Tomi K

Volltext

Phage Display Selection of Ligand Residues Important for Src Homology 3 Domain Binding Specificity von Rickles, Richard J., Botfield, Martyn C., Zhou, Xiao-Mai, Henry, Pamela A., Brugge, Joan S.

Volltext

Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation von Clancy, J P, Rowe, Steven M, Accurso, Frank J, Aitken, Moira L, Amin, Raouf S, Ashlock, Melissa A, Ballmann, Manfred, Boyle, Michael P, Bronsveld, Inez, Campbell, Preston W, De Boeck, Kris, Donaldson, Scott H, Dorkin, Henry L, Dunitz, Jordan M, Durie, Peter R, Jain, Manu, Leonard, Anissa, McCoy, Karen S, Moss, Richard B, Pilewski, Joseph M, Rosenbluth, Daniel B, Rubenstein, Ronald C, Schechter, Michael S, Botfield, Martyn, Ordoñez, Claudia L, Spencer-Green, George T, Vernillet, Laurent, Wisseh, Steve, Yen, Karl, Konstan, Michael W

Volltext

Use of hyperpolarized helium-3 MRI to assess response to ivacaftor treatment in patients with cystic fibrosis von Altes, Talissa A, Johnson, Mac, Fidler, Meredith, Botfield, Martyn, Tustison, Nicholas J, Leiva-Salinas, Carlos, de Lange, Eduard E, Froh, Deborah, Mugler, John P

Volltext

Hepatitis C pharmacogenetics: State of the art in 2010 von Afdhal, Nezam H., McHutchison, John G., Zeuzem, Stefan, Mangia, Alessandra, Pawlotsky, Jean‐Michel, Murray, Jeffrey S., Shianna, Kevin V., Tanaka, Yasuhito, Thomas, David L., Booth, David R., Goldstein, David B.

Volltext

Limited impact of IL28B genotype on response rates in telaprevir-treated patients with prior treatment failure von Pol, Stanislas, Aerssens, Jeroen, Zeuzem, Stefan, Andreone, Pietro, Lawitz, Eric J, Roberts, Stuart, Younossi, Zobair, Foster, Graham R, Focaccia, Roberto, Horban, Andrzej, Pockros, Paul J, Van Heeswijk, Rolf P.G, De Meyer, Sandra, Luo, Don, Botfield, Martyn, Beumont, Maria, Picchio, Gaston

Volltext

Telaprevir‐based treatment effects on hepatitis C virus in liver and blood von Talal, Andrew H., Dimova, Rositsa B., Zhang, Eileen Z., Jiang, Min, Penney, Marina S., Sullivan, James C., Botfield, Martyn C., Chakilam, Ananthsrinivas, Sawant, Rishikesh, Cervini, Christine M., Zeremski, Marija, Jacobson, Ira M., Kwong, Ann D.

Volltext

A signature for immune response correlates with HCV treatment outcome in Caucasian subjects von Hare, Brian J., Haseltine, Eric, Fleming, Mark, Chelsky, Daniel, McIntosh, Laura, Allard, Rene, Botfield, Martyn

Volltext

Objective Measurement of Gait Abnormalities in Huntington Disease using a Shoe-Worn Inertial Sensor (P5.291) von Hogarth, Penelope, Lenahan, Arthur, Portillo, Alicia, Ramachandran, Ravi, Stenson, Katie, Legedza, Anna, Botfield, Martyn, Horak, Fay, McNames, James, El-Gohary, Mahmoud

Volltext

Evaluating more naturalistic outcome measures: A 1-year smartphone study in multiple sclerosis von Bove, Riley, White, Charles C, Giovannoni, Gavin, Glanz, Bonnie, Golubchikov, Victor, Hujol, Johnny, Jennings, Charles, Langdon, Dawn, Lee, Michelle, Legedza, Anna, Paskavitz, James, Prasad, Sashank, Richert, John, Robbins, Allison, Roberts, Susan, Weiner, Howard, Ramachandran, Ravi, Botfield, Martyn, De Jager, Philip L

Volltext

The construction of a cysteine-less melibiose carrier from E. coli von Weissborn, Audrey C, Botfield, Martyn C, Kuroda, Masayuki, Tsuchiya, Tomofusa, Wilson, T.Hastings

Volltext