Linking Albinism and Immunity: The Secrets of Secretory Lysosomes von Stinchcombe, Jane, Bossi, Giovanna, Griffiths, Gillian M.

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The Immunological Synapse of CTL Contains a Secretory Domain and Membrane Bridges von Stinchcombe, Jane C., Bossi, Giovanna, Booth, Sarah, Griffiths, Gillian M.

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Cell-targeted PD-1 agonists that mimic PD-L1 are potent T cell inhibitors von Curnock, Adam P, Bossi, Giovanna, Kumaran, Jyothi, Bawden, Lindsay J, Figueiredo, Rita, Tawar, Rajeevkumar, Wiseman, Katherine, Henderson, Emma, Hoong, Sec Julie, Gonzalez, Veronica, Ghadbane, Hemza, Knight, David Eo, O'Dwyer, Ronan, Overton, David X, Lucato, Christina M, Smith, Nicola Mg, Reis, Carlos R, Page, Keith, Whaley, Lorraine M, McCully, Michelle L, Hearty, Stephen, Mahon, Tara M, Weber, Peter

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The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation von McCarthy, Corinna, Shepherd, Dawn, Fleire, Sebastian, Stronge, Victoria S, Koch, Michael, Illarionov, Petr A, Bossi, Giovanna, Salio, Mariolina, Denkberg, Galit, Reddington, Faye, Tarlton, Andrea, Reddy, B Gopal, Schmidt, Richard R, Reiter, Yoram, Griffiths, Gillian M, van der Merwe, P Anton, Besra, Gurdyal S, Jones, E Yvonne, Batista, Facundo D, Cerundolo, Vincenzo

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Sorting of Fas ligand to secretory lysosomes is regulated by mono-ubiquitylation and phosphorylation von Zuccato, Elisabetta, Blott, Emma J, Holt, Oliver, Sigismund, Sara, Shaw, Michael, Bossi, Giovanna, Griffiths, Gillian M

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Examining the presentation of tumor-associated antigens on peptide-pulsed T2 cells von Bossi, Giovanna, Gerry, Andrew B, Paston, Samantha J, Sutton, Deborah H, Hassan, Namir J, Jakobsen, Bent K

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A general role for Rab27a in secretory cells von Tolmachova, Tanya, Anders, Ross, Stinchcombe, Jane, Bossi, Giovanna, Griffiths, Gillian M, Huxley, Clare, Seabra, Miguel C

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Slp1 and Slp2-a Localize to the Plasma Membrane of CTL and Contribute to Secretion from the Immunological Synapse von Holt, Oliver, Kanno, Eiko, Bossi, Giovanna, Booth, Sarah, Daniele, Tiziana, Santoro, Alessandra, Arico, Maurizio, Saegusa, Chika, Fukuda, Mitsunori, Griffiths, Gillian M

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Fas ligand is targeted to secretory lysosomes via a proline-rich domain in its cytoplasmic tail von Blott, E J, Bossi, G, Clark, R, Zvelebil, M, Griffiths, G M

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The HLA A0201–restricted hTERT540–548 peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor von Purbhoo, Marco A., Li, Yi, Sutton, Deborah H., Brewer, Joanna E., Gostick, Emma, Bossi, Giovanna, Laugel, Bruno, Moysey, Ruth, Baston, Emma, Liddy, Nathaniel, Cameron, Brian, Bennett, Alan D., Ashfield, Rebecca, Milicic, Anita, Price, David A., Classon, Brendan J., Sewell, Andrew K., Jakobsen, Bent K.

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Centrosome polarization delivers secretory granules to the immunological synapse von Stinchcombe, Jane C, Majorovits, Endre, Bossi, Giovanna, Griffiths, Gillian M, Fuller, Stephen

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Polyfunctional response by ImmTAC (IMCgp100) redirected CD8+ and CD4+ T cells von Boudousquie, Caroline, Bossi, Giovanna, Hurst, Jacob M., Rygiel, Karolina A., Jakobsen, Bent K., Hassan, Namir J.

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ImmTAC-redirected tumour cell killing induces and potentiates antigen cross-presentation by dendritic cells von Bossi, Giovanna, Buisson, Sandrine, Oates, Joanne, Jakobsen, Bent K., Hassan, Namir J.

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Enhanced target-specific delivery of docetaxel-loaded nanoparticles using engineered T cell receptors von McDaid, William J, Lissin, Nikolai, Pollheimer, Ellen, Greene, Michelle, Leach, Adam, Smyth, Peter, Bossi, Giovanna, Longley, Daniel, Cole, David K, Scott, Christopher J

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Monoclonal TCR-redirected tumor cell killing von Liddy, Nathaniel, Bossi, Giovanna, Adams, Katherine J, Lissina, Anna, Mahon, Tara M, Hassan, Namir J, Gavarret, Jessie, Bianchi, Frayne C, Pumphrey, Nicholas J, Ladell, Kristin, Gostick, Emma, Sewell, Andrew K, Lissin, Nikolai M, Harwood, Naomi E, Molloy, Peter E, Li, Yi, Cameron, Brian J, Sami, Malkit, Baston, Emma E, Todorov, Penio T, Paston, Samantha J, Dennis, Rebecca E, Harper, Jane V, Dunn, Steve M, Ashfield, Rebecca, Johnson, Andy, McGrath, Yvonne, Plesa, Gabriela, June, Carl H, Kalos, Michael, Price, David A, Vuidepot, Annelise, Williams, Daniel D, Sutton, Deborah H, Jakobsen, Bent K

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Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy von Raman, Marine C C, Rizkallah, Pierre J, Simmons, Ruth, Donnellan, Zoe, Dukes, Joseph, Bossi, Giovanna, Le Provost, Gabrielle S, Todorov, Penio, Baston, Emma, Hickman, Emma, Mahon, Tara, Hassan, Namir, Vuidepot, Annelise, Sami, Malkit, Cole, David K, Jakobsen, Bent K.

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An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific (ImmTAC) molecules von Harper, Jane, Adams, Katherine J, Bossi, Giovanna, Wright, Debbie E, Stacey, Andrea R, Bedke, Nicole, Martinez-Hague, Ruth, Blat, Dan, Humbert, Laure, Buchanan, Hazel, Le Provost, Gabrielle S, Donnellan, Zoe, Carreira, Ricardo J, Paston, Samantha J, Weigand, Luise U, Canestraro, Martina, Sanderson, Joseph P, Botta Gordon-Smith, Sophie, Lowe, Kate L, Rygiel, Karolina A, Powlesland, Alex S, Vuidepot, Annelise, Hassan, Namir J, Cameron, Brian J, Jakobsen, Bent K, Dukes, Joseph

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Polyfunctional response by Imm TAC ( IMC gp100) redirected CD 8 + and CD 4 + T cells von Boudousquie, Caroline, Bossi, Giovanna, Hurst, Jacob M., Rygiel, Karolina A., Jakobsen, Bent K., Hassan, Namir J.

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Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors von Yang, Hongbing, Buisson, Sandrine, Bossi, Giovanna, Wallace, Zoë, Hancock, Gemma, So, Chun, Ashfield, Rebecca, Vuidepot, Annelise, Mahon, Tara, Molloy, Peter, Oates, Joanne, Paston, Samantha J, Aleksic, Milos, Hassan, Namir J, Jakobsen, Bent K, Dorrell, Lucy

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58-LB: ß-Cell Targeted Immune Suppressive PD-1 Bispecific Agonists: A Novel Approach to Treat Type 1 Diabetes von BOSSI, GIOVANNA, CURNOCK, ADAM P., WEBER, PETER, KUMARAN, JYOTHI, BAWDEN, LINDSAY J., FIGUEIREDO, RITA, WISEMAN, KATHERINE E., O’DWYER, RONAN, OVERTON, DAVID, GONZALEZ, VERONICA, LUCATO, CHRISTINA M.A., PAGE, KEITH, SMITH, NICOLA, WHALEY, LORRAINE, GHADBANE, HEMZA, KNIGHT, DAVID, HENDERSON, EMMA, HEARTY, STEPHEN, MAHON, TARA

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