High-Throughput Activity Assay for Screening Inhibitors of the SARS-CoV‑2 Mac1 Macrodomain von Dasovich, Morgan, Zhuo, Junlin, Goodman, Jack A., Thomas, Ajit, McPherson, Robert Lyle, Jayabalan, Aravinth Kumar, Busa, Veronica F., Cheng, Shang-Jung, Murphy, Brennan A., Redinger, Karli R., Alhammad, Yousef M. O., Fehr, Anthony R., Tsukamoto, Takashi, Slusher, Barbara S., Bosch, Jürgen, Wei, Huijun, Leung, Anthony K. L.

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Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages von Winnicki, Anna C., Dietrich, Melanie H., Yeoh, Lee M., Carias, Lenore L., Roobsoong, Wanlapa, Drago, Chiara L., Malachin, Alyssa N., Redinger, Karli R., Feufack-Donfack, Lionel Brice, Baldor, Lea, Jung, Nicolai C., McLaine, Olivia S., Skomorovska-Prokvolit, Yelenna, Orban, Agnes, Opi, D. Herbert, Kirtley, Payton, Nielson, Kiersey, Aleshnick, Maya, Zanghi, Gigliola, Rezakhani, Nastaran, Vaughan, Ashley M., Wilder, Brandon K., Sattabongkot, Jetsumon, Tham, Wai-Hong, Popovici, Jean, Beeson, James G., Bosch, Jürgen, King, Christopher L.

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Identification of an Atg8-Atg3 Protein–Protein Interaction Inhibitor from the Medicines for Malaria Venture Malaria Box Active in Blood and Liver Stage Plasmodium falciparum Parasi... von Hain, Adelaide U.P, Bartee, David, Sanders, Natalie G, Miller, Alexia S, Sullivan, David J, Levitskaya, Jelena, Meyers, Caren Freel, Bosch, Jürgen

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The Conserved Macrodomain Is a Potential Therapeutic Target for Coronaviruses and Alphaviruses von Leung, Anthony K L, Griffin, Diane E, Bosch, Jürgen, Fehr, Anthony R

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Duffy antigen is expressed during erythropoiesis in Duffy-negative individuals von Dechavanne, Celia, Dechavanne, Sebastien, Bosch, Jürgen, Metral, Sylvain, Redinger, Karli R, Watson, Quentin D, Ratsimbasoa, Arsene C, Roeper, Brooke, Krishnan, Sushma, Fong, Rich, Bennett, Seth, Carias, Lenore, Chen, Edwin, Salinas, Nichole D, Ghosh, Anil, Tolia, Niraj H, Woost, Philip G, Jacobberger, James W, Colin, Yves, Gamain, Benoit, King, Christopher L, Zimmerman, Peter A

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Novel Antifungal Compounds Discovered in Medicines for Malaria Venture's Malaria Box von Jung, Eric H, Meyers, David J, Bosch, Jürgen, Casadevall, Arturo

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Human monoclonal antibodies inhibit invasion of transgenic Plasmodium knowlesi expressing Plasmodium vivax Duffy binding protein von Watson, Quentin D, Carias, Lenore L, Malachin, Alyssa, Redinger, Karli R, Bosch, Jürgen, Bardelli, Martino, Baldor, Lea, Feufack-Donfack, Lionel Brice, Popovici, Jean, Moon, Robert W, Draper, Simon J, Zimmerman, Peter A, King, Christopher L

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Voltage-gated potassium channel proteins and stereoselective S-nitroso-l-cysteine signaling von Gaston, Benjamin, Smith, Laura, Bosch, Jürgen, Seckler, James, Kunze, Diana, Kiselar, Janna, Marozkina, Nadzeya, Hodges, Craig A, Wintrobe, Patrick, McGee, Kellen, Morozkina, Tatiana S, Burton, Spencer T, Lewis, Tristan, Strassmaier, Timothy, Getsy, Paulina, Bates, James N, Lewis, Stephen J

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Development of small molecule inhibitors targeting PBX1 transcription signaling as a novel cancer therapeutic strategy von Shen, Yao-An, Jung, Jin, Shimberg, Geoffrey D., Hsu, Fang-Chi, Rahmanto, Yohan Suryo, Gaillard, Stephanie L., Hong, Jiaxin, Bosch, Jürgen, Shih, Ie-Ming, Chuang, Chi-Mu, Wang, Tian-Li

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The bactofilin cytoskeleton protein BacM of Myxococcus xanthus forms an extended β-sheet structure likely mediated by hydrophobic interactions von Zuckerman, David M, Boucher, Lauren E, Xie, Kefang, Engelhardt, Harald, Bosch, Jürgen, Hoiczyk, Egbert

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A BAC Transgene Expressing Human CFTR under Control of Its Regulatory Elements Rescues Cftr Knockout Mice von Gawenis, Lara R., Hodges, Craig A., McHugh, Daniel R., Valerio, Dana M., Miron, Alexander, Cotton, Calvin U., Liu, Jinghua, Walker, Nancy M., Strubberg, Ashlee M., Gillen, Austin E., Mutolo, Michael J., Kotzamanis, George, Bosch, Jürgen, Harris, Ann, Drumm, Mitchell L., Clarke, Lane L.

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Structure-Based Screening of Plasmodium berghei Glutathione S-Transferase Identifies CB-27 as a Novel Antiplasmodial Compound von Colón-Lorenzo, Emilee E, Colón-López, Daisy D, Vega-Rodríguez, Joel, Dupin, Alice, Fidock, David A, Baerga-Ortiz, Abel, Ortiz, José G, Bosch, Jürgen, Serrano, Adelfa E

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Avidity maturation of humoral response following primary and booster doses of BNT162b2 mRNA vaccine among nursing home residents and healthcare workers von Oyebanji, Oladayo A., Sundheimer, Nicholas, Ragavapuram, Vaishnavi, Wilson, Brigid M., Abul, Yasin, Gravenstein, Stefan, Bosch, Jürgen, King, Christopher L., Canaday, David H.

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The structure of Plasmodium falciparum 3D7_0606800 reveals a bi‐lobed architecture that supports re‐annotation as a Venus Flytrap protein von Parker, Michelle L., Ramaswamy, Raghavendran, van Gordon, Kyle, Powell, Cameron J., Bosch, Jürgen, Boulanger, Martin J.

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Discovery of Plasmodium (M)TRAP–Aldolase Interaction Stabilizers Interfering with Sporozoite Motility and Invasion von Boucher, Lauren E, Hopp, Christine S, Muthinja, Julianne Mendi, Frischknecht, Friedrich, Bosch, Jürgen

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Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box von Çelik, Haydar, Hong, Sung-Hyeok, Colón-López, Daisy D, Han, Jenny, Kont, Yasemin Saygideger, Minas, Tsion Z, Swift, Matthew, Paige, Mikell, Glasgow, Eric, Toretsky, Jeffrey A, Bosch, Jürgen, Üren, Aykut

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Structural characterization and inhibition of the Plasmodium Atg8–Atg3 interaction von Hain, Adelaide U.P., Weltzer, Ryan R., Hammond, Holly, Jayabalasingham, Bamini, Dinglasan, Rhoel R., Graham, David R.M., Colquhoun, David R., Coppens, Isabelle, Bosch, Jürgen

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Virtual Screening and Experimental Validation Identify Novel Inhibitors of the Plasmodium falciparum Atg8-Atg3 Protein-Protein Interaction von Hain, Adelaide U. P., Miller, Alexia S., Levitskaya, Jelena, Bosch, Jürgen

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PPI inhibitor and stabilizer development in human diseases von Bosch, Jürgen

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Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses von Everts, Bart, Perona-Wright, Georgia, Smits, Hermelijn H, Hokke, Cornelis H, van der Ham, Alwin J, Fitzsimmons, Colin M, Doenhoff, Michael J, van der Bosch, Jürgen, Mohrs, Katja, Haas, Helmut, Mohrs, Markus, Yazdanbakhsh, Maria, Schramm, Gabriele

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