FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation von Gaschler, Michael M., Andia, Alexander A., Liu, Hengrui, Csuka, Joleen M., Hurlocker, Brisa, Vaiana, Christopher A., Heindel, Daniel W., Zuckerman, Dylan S., Bos, Pieter H., Reznik, Eduard, Ye, Ling F., Tyurina, Yulia Y., Lin, Annie J., Shchepinov, Mikhail S., Chan, Amy Y., Peguero-Pereira, Eveliz, Fomich, Maksim A., Daniels, Jacob. D., Bekish, Andrei V., Shmanai, Vadim V., Kagan, Valerian E., Mahal, Lara K., Woerpel, K. A., Stockwell, Brent R.

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Reaction-Based Enumeration, Active Learning, and Free Energy Calculations To Rapidly Explore Synthetically Tractable Chemical Space and Optimize Potency of Cyclin-Dependent Kinase... von Konze, Kyle D, Bos, Pieter H, Dahlgren, Markus K, Leswing, Karl, Tubert-Brohman, Ivan, Bortolato, Andrea, Robbason, Braxton, Abel, Robert, Bhat, Sathesh

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Catalytic Asymmetric Conjugate Addition/Oxidative Dearomatization Towards Multifunctional Spirocyclic Compounds von Rudolph, Alena, Bos, Pieter H., Meetsma, Auke, Minnaard, Adriaan J., Feringa, Ben L.

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Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents von Bos, Pieter H., Lowry, Emily R., Costa, Jonathon, Thams, Sebastian, Garcia-Diaz, Alejandro, Zask, Arie, Wichterle, Hynek, Stockwell, Brent R.

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Multivalent Small-Molecule Pan-RAS Inhibitors von Welsch, Matthew E., Kaplan, Anna, Chambers, Jennifer M., Stokes, Michael E., Bos, Pieter H., Zask, Arie, Zhang, Yan, Sanchez-Martin, Marta, Badgley, Michael A., Huang, Christine S., Tran, Timothy H., Akkiraju, Hemanth, Brown, Lewis M., Nandakumar, Renu, Cremers, Serge, Yang, Wan Seok, Tong, Liang, Olive, Kenneth P., Ferrando, Adolfo, Stockwell, Brent R.

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Combining Cloud-Based Free-Energy Calculations, Synthetically Aware Enumerations, and Goal-Directed Generative Machine Learning for Rapid Large-Scale Chemical Exploration and Optim... von Ghanakota, Phani, Bos, Pieter H, Konze, Kyle D, Staker, Joshua, Marques, Gabriel, Marshall, Kyle, Leswing, Karl, Abel, Robert, Bhat, Sathesh

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K‑RasG12D Has a Potential Allosteric Small Molecule Binding Site von Feng, Huizhong, Zhang, Yan, Bos, Pieter H, Chambers, Jennifer M, Dupont, Marcel M, Stockwell, Brent R

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Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells von Shimada, Kenichi, Reznik, Eduard, Stokes, Michael E., Krishnamoorthy, Lakshmi, Bos, Pieter H., Song, Yuyu, Quartararo, Christine E., Pagano, Nen C., Carpizo, Darren R., deCarvalho, Ana C., Lo, Donald C., Stockwell, Brent R.

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Risk for re-revision and type of antibiotic-loaded bone cement in hip or knee arthroplasty revisions: report of the Dutch Arthroplasty Register von Bos, Pieter K, Spekenbrink-Spooren, Anneke, Croughs, Peter, Bierma-Zeinstra, Sita M A, Reijman, Max, Van Oldenrijk, Jakob

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The effectiveness of high molecular weight hyaluronic acid for knee osteoarthritis in patients in the working age: a randomised controlled trial von Hermans, Job, Bierma-Zeinstra, Sita M A, Bos, Pieter K, Niesten, Dieu Donne, Verhaar, Jan A N, Reijman, Max

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Phenotypic spectrum of the SMAD3-related aneurysms–osteoarthritis syndrome von van de Laar, Ingrid M B H, van der Linde, Denise, Oei, Edwin H G, Bos, Pieter K, Bessems, Johannes H, Bierma-Zeinstra, Sita M, van Meer, Belle L, Pals, Gerard, Oldenburg, Rogier A, Bekkers, Jos A, Moelker, Adriaan, de Graaf, Bianca M, Matyas, Gabor, Frohn-Mulder, Ingrid M E, Timmermans, Janneke, Hilhorst-Hofstee, Yvonne, Cobben, Jan M, Bruggenwirth, Hennie T, van Laer, Lut, Loeys, Bart, De Backer, Julie, Coucke, Paul J, Dietz, Harry C, Willems, Patrick J, Oostra, Ben A, De Paepe, Anne, Roos-Hesselink, Jolien W, Bertoli-Avella, Aida M, Wessels, Marja W

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AutoDesigner, a De Novo Design Algorithm for Rapidly Exploring Large Chemical Space for Lead Optimization: Application to the Design and Synthesis of d‑Amino Acid Oxidase Inhibitor... von Bos, Pieter H, Houang, Evelyne M, Ranalli, Fabio, Leffler, Abba E, Boyles, Nicholas A, Eyrich, Volker A, Luria, Yuval, Katz, Dana, Tang, Haifeng, Abel, Robert, Bhat, Sathesh

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Is T1ρ Mapping an Alternative to Delayed Gadolinium-enhanced MR Imaging of Cartilage in the Assessment of Sulphated Glycosaminoglycan Content in Human Osteoarthritic Knees? An in V... von van Tiel, Jasper, Kotek, Gyula, Reijman, Max, Bos, Pieter K, Bron, Esther E, Klein, Stefan, Nasserinejad, Kazem, van Osch, Gerjo J V M, Verhaar, Jan A N, Krestin, Gabriel P, Weinans, Harrie, Oei, Edwin H G

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AutoDesigner - Core Design, a De Novo Design Algorithm for Chemical Scaffolds: Application to the Design and Synthesis of Novel Selective Wee1 Inhibitors von Bos, Pieter H., Ranalli, Fabio, Flood, Emelie, Watts, Shawn, Inoyama, Daigo, Knight, Jennifer L., Clark, Anthony J., Placzeck, Andrew, Wang, Jiashi, Gerasyuto, Aleksey I., Silvergleid, Sarah, Yin, Wu, Sun, Shaoxian, Abel, Robert, Bhat, Sathesh

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Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using an In Silico Enabled Drug Discovery Platform von Igawa, Hideyuki, Konst, Zef A., Therrien, Eric, Shelley, Mee, Koldsø, Heidi, Bos, Pieter H., Negri, Ana, Verras, Andreas, Guo, Jiaye, Dahlgren, Markus K., Levinson, Adam, Parr, Brendan T., Kurhade, Suresh E., Latthe, Prashant, Shetty, Rajesha, Santhanakrishnan, Sridhar, Amberg-Johnson, Katherine, Futran, Alan S., Atsriku, Christian, Pelletier, Robert D., Liu, Zhijian, Bell, Jeffrey A., Bhat, Sathesh, Svensson, Mats, Gerasyuto, Aleksey I.

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Human rotavirus vaccine Rotarix™ provides protection against diverse circulating rotavirus strains in African infants: a randomized controlled trial von Steele, Andrew Duncan, Neuzil, Kathleen M, Cunliffe, Nigel A, Madhi, Shabir A, Bos, Pieter, Ngwira, Bagrey, Witte, Desiree, Todd, Stacy, Louw, Cheryl, Kirsten, Mari, Aspinall, Sanet, Van Doorn, Leen Jan, Bouckenooghe, Alain, Suryakiran, Pemmaraju V, Han, Htay Htay

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Synthetic Study toward Total Synthesis of (±)-Germine: Synthesis of (±)-4-Methylenegermine von Stork, Gilbert, Yamashita, Ayako, Hanson, Robert M, Phan, Ly, Phillips, Eifion, Dubé, Daniel, Bos, Pieter H, Clark, Andrew J, Gough, Maxwell, Greenlee, Mark L, Jiang, Yimin, Jones, Keith, Kitamura, Masato, Leonard, John, Liu, Tongzhu, Parsons, Philip J, Venkatesan, Aranapakam M

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Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) shows no change in cartilage structural composition after viscosupplementation in patients with early-stage knee osteoarthrit... von van Tiel, Jasper, Reijman, Max, Bos, Pieter K, Hermans, Job, van Buul, Gerben M, Bron, Esther E, Klein, Stefan, Verhaar, Jan A N, Krestin, Gabriel P, Bierma-Zeinstra, Sita M A, Weinans, Harrie, Kotek, Gyula, Oei, Edwin H G

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K-Ras G12D Has a Potential Allosteric Small Molecule Binding Site von Feng, Huizhong, Zhang, Yan, Bos, Pieter H, Chambers, Jennifer M, Dupont, Marcel M, Stockwell, Brent R

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Copper-catalyzed asymmetric ring opening of oxabicyclic alkenes with organolithium reagents von Bos, Pieter H, Rudolph, Alena, Pérez, Manuel, Fañanás-Mastral, Martín, Harutyunyan, Syuzanna R, Feringa, Ben L

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