Deubiquitinase Inhibition by Small-Molecule WP1130 Triggers Aggresome Formation and Tumor Cell Apoptosis von KAPURIA, Vaibhav, PETERSON, Luke F, DEXING FANG, BORNMANN, William G, TALPAZ, Moshe, DONATO, Nicholas J

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NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachone von Bey, Erik A, Bentle, Melissa S, Reinicke, Kathryn E, Dong, Ying, Yang, Chin-Rang, Girard, Luc, Minna, John D, Bornmann, William G, Gao, Jinming, Boothman, David A

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Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo von Meng, Jieru, Dai, Bingbing, Fang, Bingliang, Bekele, B Nebiyou, Bornmann, William G, Sun, Duoli, Peng, Zhenghong, Herbst, Roy S, Papadimitrakopoulou, Vassiliki, Minna, John D, Peyton, Michael, Roth, Jack A

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Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis von Sun, Hanshi, Kapuria, Vaibhav, Peterson, Luke F., Fang, Dexing, Bornmann, William G., Bartholomeusz, Geoffrey, Talpaz, Moshe, Donato, Nicholas J.

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Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apop... von Chen, Min‐Yu, Liao, Warren S.‐L., Lu, Zhen, Bornmann, William G., Hennessey, Violeta, Washington, Michele N., Rosner, Gary L., Yu, Yinhua, Ahmed, Ahmed Ashour, Bast, Robert C.

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Association Between Imatinib-Resistant BCR-ABL Mutation-Negative Leukemia and Persistent Activation of LYN Kinase von Wu, Ji, Meng, Feng, Kong, Ling-Yuan, Peng, Zhenghong, Ying, Yunming, Bornmann, William G., Darnay, Bryant G., Lamothe, Betty, Sun, Hanshi, Talpaz, Moshe, Donato, Nicholas J.

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STAT3 Mediates Resistance to MEK Inhibitor through MicroRNA miR-17 von BINGBING DAI, JIERU MENG, PEYTON, Michael, GIRARD, Luc, BORNMANN, William G, LIN JI, MINNA, John D, BINGLIANG FANG, ROTH, Jack A

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Aggresome disruption : A novel strategy to enhance bortezomib- induced apoptosis in pancreatic cancer cells von NAWROCKI, Steffan T, CAREW, Jennifer S, XIONG, Henry, ABBRUZZESE, James L, MCCONKEY, David J, PINO, Maria S, HIGHSHAW, Ralph A, ANDTBACKA, Robert H. I, DUNNER, Kenneth, PAL, Ashutosh, BORNMANN, William G, CHIAO, Paul J, PENG HUANG

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Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation von Antonio, Tamara, Childers, Steven R, Rothman, Richard B, Dersch, Christina M, King, Christine, Kuehne, Martin, Bornmann, William G, Eshleman, Amy J, Janowsky, Aaron, Simon, Eric R, Reith, Maarten E A, Alper, Kenneth

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Intratumoral Delivery of β-Lapachone via Polymer Implants for Prostate Cancer Therapy von Dong, Ying, Chin, Shook-Fong, Blanco, Elvin, Bey, Erik A, Kabbani, Wareef, Xie, Xian-Jin, Bornmann, William G, Boothman, David A, Gao, Jinming

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Combining PCI-24781, a Novel Histone Deacetylase Inhibitor, with Chemotherapy for the Treatment of Soft Tissue Sarcoma von Lopez, Gonzalo, Liu, Juehui, Ren, Wenhong, Wei, Wei, Wang, Suizhao, Lahat, Guy, Zhu, Quan-Sheng, Bornmann, William G, McConkey, David J, Pollock, Raphael E, Lev, Dina C

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Gleevec Inhibits β-Amyloid Production but Not Notch Cleavage von Netzer, William J., Dou, Fei, Cai, Dongming, Veach, Darren, Jean, Stephanie, Li, Yueming, Bornmann, William G., Clarkson, Bayard, Xu, Huaxi, Greengard, Paul

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Activity of lapatinib is independent of EGFR expression level in HER2-overexpressing breast cancer cells von Zhang, Dongwei, Pal, Ashutosh, Bornmann, William G, Yamasaki, Fumiyuki, Esteva, Francisco J, Hortobagyi, Gabriel N, Bartholomeusz, Chandra, Ueno, Naoto T

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Dual targeting of AKT and mammalian target of rapamycin: A potential therapeutic approach for malignant peripheral nerve sheath tumor von Zou, Changye Y, Smith, Kerrington D, Zhu, Quan-Sheng, Liu, Jun, McCutcheon, Ian E, Slopis, John M, Meric-Bernstam, Funda, Peng, Zhenghong, Bornmann, William G, Mills, Gordon B, Lazar, Alexander J, Pollock, Raphael E, Lev, Dina

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Loss of p53 Impedes the Antileukemic Response to BCR-ABL Inhibition von Wendel, Hans-Guido, de Stanchina, Elisa, Cepero, Enriqué, Ray, Sagarika, Emig, Michael, Fridman, Jordan S., Veach, Darren R., Bornmann, William G., Clarkson, Bayard, McCombie, W. Richard, Kogan, Scott C., Hochhaus, Andreas, Lowe, Scott W.

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Activity of Dual SRC-ABL Inhibitors Highlights the Role of BCR/ABL Kinase Dynamics in Drug Resistance von Azam, Mohammad, Nardi, Valentina, Shakespeare, William C., Metcalf, Chester A., Bohacek, Regine S., Wang, Yihan, Sundaramoorthi, Raji, Sliz, Piotr, Veach, Darren R., Bornmann, William G., Clarkson, Bayard, Dalgarno, David C., Sawyer, Tomi K., Daley, George Q.

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Total Synthesis of 5-N-Acetylardeemin and Amauromine:  Practical Routes to Potential MDR Reversal Agents von Depew, Kristopher M, Marsden, Stephen P, Zatorska, Danuta, Zatorski, Andrzej, Bornmann, William G, Danishefsky, Samuel J

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Two Distinct Phosphorylation Pathways Have Additive Effects on Abl Family Kinase Activation von Tanis, Keith Q., Veach, Darren, Duewel, Henry S., Bornmann, William G., Koleske, Anthony J.

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Degrasyn-like symmetrical compounds: Possible therapeutic agents for multiple myeloma (MM-I) von Peng, Zhenghong, Maxwell, David S., Sun, Duoli, Bhanu Prasad, Basvoju A., Schuber, Paul T., Pal, Ashutosh, Ying, Yunming, Han, Dongmei, Gao, Liwei, Wang, Shimei, Levitzki, Alexander, Kapuria, Vaibhav, Talpaz, Moshe, Young, Matthew, Showalter, Hollis D., Donato, Nicholas J., Bornmann, William G.

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Asymmetric synthesis of the C1–C6 portion of the psymberin using an Evans chiral auxiliary von Pal, Ashutosh, Peng, Zhenghong, Schuber, Paul T., Bhanu Prasad, Basvoju A., Bornmann, William G.

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