XRN2 Links Transcription Termination to DNA Damage and Replication Stress von Morales, Julio C, Richard, Patricia, Patidar, Praveen L, Motea, Edward A, Dang, Tuyen T, Manley, James L, Boothman, David A

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NQO1 targeting prodrug triggers innate sensing to overcome checkpoint blockade resistance von Li, Xiaoguang, Liu, Zhida, Zhang, Anli, Han, Chuanhui, Shen, Aijun, Jiang, Lingxiang, Boothman, David A., Qiao, Jian, Wang, Yang, Huang, Xiumei, Fu, Yang-Xin

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Overcoming Endosomal Barrier by Amphotericin B-Loaded Dual pH-Responsive PDMA-b-PDPA Micelleplexes for siRNA Delivery von Yu, Haijun, Zou, Yonglong, Wang, Yiguang, Huang, Xiaonan, Huang, Gang, Sumer, Baran D, Boothman, David A, Gao, Jinming

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Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia von Ding, Huiying, Yu, Haijun, Dong, Ying, Tian, Ruhai, Huang, Gang, Boothman, David A., Sumer, Baran D., Gao, Jinming

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Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors von Huang, Xiumei, Motea, Edward A., Moore, Zachary R., Yao, Jun, Dong, Ying, Chakrabarti, Gaurab, Kilgore, Jessica A., Silvers, Molly A., Patidar, Praveen L., Cholka, Agnieszka, Fattah, Farjana, Cha, Yoonjeong, Anderson, Glenda G., Kusko, Rebecca, Peyton, Michael, Yan, Jingsheng, Xie, Xian-Jin, Sarode, Venetia, Williams, Noelle S., Minna, John D., Beg, Muhammad, Gerber, David E., Bey, Erik A., Boothman, David A.

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Focal Adhesion Kinase Regulates the DNA Damage Response and Its Inhibition Radiosensitizes Mutant KRAS Lung Cancer von Tang, Ke-Jing, Constanzo, Jerfiz D, Venkateswaran, Niranjan, Melegari, Margherita, Ilcheva, Mariya, Morales, Julio C, Skoulidis, Ferdinandos, Heymach, John V, Boothman, David A, Scaglioni, Pier Paolo

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Depleting Tumor-NQO1 Potentiates Anoikis and Inhibits Growth of NSCLC von Madajewski, Brian, Boatman, Michael A, Chakrabarti, Gaurab, Boothman, David A, Bey, Erik A

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Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis von Xie, Daxing, Gore, Crystal, Liu, Jun, Pong, Rey-Chen, Mason, Ralph, Hao, Guiyang, Long, Michael, Kabbani, Wareef, Yu, Luyang, Zhang, Haifeng, Chen, Hong, Sun, Xiankai, Boothman, David A, Min, Wang, Hsieh, Jer-Tsong

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The transcription factor TFII-I promotes DNA translesion synthesis and genomic stability von Fattah, Farjana J, Hara, Kodai, Fattah, Kazi R, Yang, Chenyi, Wu, Nan, Warrington, Ross, Chen, David J, Zhou, Pengbo, Boothman, David A, Yu, Hongtao

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Nanoscopic micelle delivery improves the photophysical properties and efficacy of photodynamic therapy of protoporphyrin IX von Ding, Huiying, Sumer, Baran D., Kessinger, Chase W., Dong, Ying, Huang, Gang, Boothman, David A., Gao, Jinming

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NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachone von Bey, Erik A, Bentle, Melissa S, Reinicke, Kathryn E, Dong, Ying, Yang, Chin-Rang, Girard, Luc, Minna, John D, Bornmann, William G, Gao, Jinming, Boothman, David A

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cRGD-Functionalized Polymer Micelles for Targeted Doxorubicin Delivery von Nasongkla, Norased, Shuai, Xintao, Ai, Hua, Weinberg, Brent D., Pink, John, Boothman, David A., Gao, Jinming

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EGFRvIII and DNA Double-Strand Break Repair: A Molecular Mechanism for Radioresistance in Glioblastoma von MUKHERJEE, Bipasha, MCELLIN, Brian, BOOTHMAN, David A, FURNARI, Frank, CAVENEE, Webster K, BACHOO, Robert M, BURMA, Sandeep, CAMACHO, Cristel V, TOMIMATSU, Nozomi, SIRASANAGANDALA, Shyam, NANNEPAGA, Suraj, HATANPAA, Kimmo J, MICKEY, Bruce, MADDEN, Christopher, MAHER, Elizabeth

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Stress-induced Premature Senescence(SIPS)-Influence of SIPS on Radiotherapy von Suzuki, Masatoshi, Boothman, David A

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Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone von Torrente, Laura, Prieto-Farigua, Nicolas, Falzone, Aimee, Elkins, Cody M., Boothman, David A., Haura, Eric B., DeNicola, Gina M.

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Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Blockade Is an Effective Radiosensitizing Strategy for the Treatment of Non―Small Cell Lung Cancer Harboring K-RAS Muta... von KONSTANTINIDOU, Georgia, BEY, Erik A, RABELLINO, Andrea, SCHUSTER, Katja, MAIRA, Michael S, GAZDAR, Adi F, AMICI, Augusto, BOOTHMAN, David A, SCAGLIONI, Pier Paolo

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Synergistic Effect of β-Lapachone and Aminooxyacetic Acid on Central Metabolism in Breast Cancer von Chang, Mario C, Mahar, Rohit, McLeod, Marc A, Giacalone, Anthony G, Huang, Xiumei, Boothman, David A, Merritt, Matthew E

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ATM regulates insulin-like growth factor 1-secretory clusterin (IGF-1-sCLU) expression that protects cells against senescence von Luo, Xiuquan, Suzuki, Masatoshi, Ghandhi, Shanaz A, Amundson, Sally A, Boothman, David A

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Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer von Wang, Miao, Topalovski, Mary, Toombs, Jason E, Wright, Christopher M, Moore, Zachary R, Boothman, David A, Yanagisawa, Hiromi, Wang, Huamin, Witkiewicz, Agnieszka, Castrillon, Diego H, Brekken, Rolf A

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Intracellular Clusterin Inhibits Mitochondrial Apoptosis by Suppressing p53-Activating Stress Signals and Stabilizing the Cytosolic Ku70-Bax Protein Complex von Trougakos, Ioannis P, Lourda, Magda, Antonelou, Marianna H, Kletsas, Dimitris, Gorgoulis, Vassilis G, Papassideri, Issidora S, Zou, Yonglong, Margaritis, Lukas H, Boothman, David A, Gonos, Efstathios S

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