Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes von van Eijk, Maarten, Boosman, René J., Schinkel, Alfred H., Huitema, Alwin D. R., Beijnen, Jos H.

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Exposure–Response Analysis of Osimertinib in EGFR Mutation Positive Non-Small Cell Lung Cancer Patients in a Real-Life Setting von Boosman, René J., Jebbink, Merel, Veldhuis, Wouter B., Groenland, Stefanie L., van Veggel, Bianca A. M. H., Moeskops, Pim, de Langen, Adrianus J., Beijnen, Jos H., Smit, Egbert F., Huitema, Alwin D. R., Steeghs, Neeltje

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Thyroid hormone receptor alpha modulates fibrogenesis in hepatic stellate cells von Manka, Paul, Coombes, Jason D., Sydor, Svenja, Swiderska‐Syn, Marzena K., Best, Jan, Gauthier, Karine, Grunsven, Leo A., Oo, Ye H., Wang, Cindy, Diehl, Anna M., Hönes, Georg S., Moeller, Lars C., Figge, Anja, Boosman, René J., Faber, Klaas N., Tannapfel, Andrea, Goetze, Oliver, Aspichueta, Patricia, Lange, Christian M., Canbay, Ali, Syn, Wing‐Kin

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Prediction of the pharmacokinetics of pemetrexed with a low test dose: A proof‐of‐concept study von Boosman, René J., Rouw, Nikki, Huitema, Alwin D. R., Burgers, Jacobus A., Heine, Rob

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Cumulative pemetrexed dose increases the risk of nephrotoxicity von de Rouw, N., Boosman, R.J., van de Bruinhorst, H., Biesma, B., van den Heuvel, M.M., Burger, D.M., Hilbrands, L.B., ter Heine, R., Derijks, H.J.

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A comparison of the renal function biomarkers serum creatinine, pro-enkephalin and cystatin C to predict clearance of pemetrexed von de Rouw, N., Beunders, R., Hartmann, O., Schulte, J., Boosman, R. J., Derijks, H. J., Burger, D. M., van den Heuvel, M. M., Hilbrands, L. B., Pickkers, P., ter Heine, R.

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The Pharmacoeconomic Benefits of Pemetrexed Dose Individualization in Patients With Lung Cancer von Rouw, Nikki, Boer, Merel, Boosman, René J., Heuvel, Michel M., Burger, David M., Lieverse, Joris E., Derijks, Hieronymus J., Frederix, Geert W.J., Heine, Rob

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Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib von Boosman, René J., de Gooijer, Cornedine J., Groenland, Stefanie L., Burgers, Jacobus A., Baas, Paul, van der Noort, Vincent, Beijnen, Jos H., Huitema, Alwin D.R., Steeghs, Neeltje

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Optimized Dosing: The Next Step in Precision Medicine in Non-Small-Cell Lung Cancer von Boosman, René J., Burgers, Jacobus A., Smit, Egbert F., Steeghs, Neeltje, van der Wekken, Anthonie J., Beijnen, Jos H., Huitema, Alwin D. R., ter Heine, Rob

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Increased drug load and polymer compatibility of bilayered orodispersible films von Carolina Visser, J., Weggemans, Oekie A.F., Boosman, René J., Loos, Katja U., Frijlink, Henderik W., Woerdenbag, Herman J.

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Toxicity of pemetrexed during renal impairment explained—Implications for safe treatment von Boosman, René J., Dorlo, Thomas P. C., Rouw, Nikki, Burgers, Jacobus A., Dingemans, Anne‐Marie C., Heuvel, Michel M., Hendriks, Lizza E. L., Biesma, Bonne, Aerts, Joachim G. J. V., Croes, Sander, Mathijssen, Ron H. J., Huitema, Alwin D. R., Heine, Rob

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Is age just a number? A population pharmacokinetic study of gemcitabine von Boosman, René J., Crombag, Marie-Rose B. S., van Erp, Nielka P., Beijnen, Jos H., Steeghs, Neeltje, Huitema, Alwin D. R.

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The digital scribe in clinical practice: a scoping review and research agenda von van Buchem, Marieke M., Boosman, Hileen, Bauer, Martijn P., Kant, Ilse M. J., Cammel, Simone A., Steyerberg, Ewout W.

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Optimisation of chemotherapy in the era of immunotherapy von Boosman, René, Burgers, Jacobus Sjaak Adrianus

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Renal function-based versus standard dosing of pemetrexed: a randomized controlled trial von de Rouw, Nikki, Boosman, René J., Burgers, Jacobus A., Huitema, Alwin D. R., Dingemans, Anne-Marie C., Derijks, Hieronymus. J., Burger, David M., Piet, Berber, Hendriks, Lizza E. L., Biesma, Bonne, Pruis, Melinda A., Dumoulin, Daphne W., Croes, Sander, Mathijssen, Ron H. J., van den Heuvel, Michel M., ter Heine, Rob

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Hyperhydration with cisplatin does not influence pemetrexed exposure von Rouw, Nikki, Derijks, Hieronymus J., Hilbrands, Luuk B., Boosman, René J., Piet, Berber, Koolen, Stijn L. W., Burgers, Jacobus A., Dingemans, Anne‐Marie C., Heuvel, Michel M., Hendriks, Lizza E. L., Aerts, Joachim G. J. V., Croes, Sander, Mathijssen, Ron H. J., Huitema, Alwin D. R., Burger, David M., Biesma, Bonne, Heine, Rob

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A Population Pharmacokinetic Study to Evaluate Doxorubicin Exposure Across All Age Groups von Mohmaed Ali, Ma Ida, Nijstad, A Laura, Boosman, René J, Crombag, Marie-Rose B S, Barnett, Shelby, Veal, Gareth J, Lalmohamed, Arief, van Erp, Nielka P, Steeghs, Neeltje, Zwaan, C Michel, Beijnen, Jos H, Siebinga, Hinke, Huitema, Alwin D R

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Thyroid hormone in the regulation of hepatocellular carcinoma and its microenvironment von Manka, P., Coombes, J.D., Boosman, R., Gauthier, K., Papa, S., Syn, W.K.

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Osimertinib Plasma Trough Concentration in Relation to Brain Metastases Development in Patients With Advanced EGFR-Mutated NSCLC von Gulikers, Judith L., Veerman, G.D. Marijn, Jebbink, Merel, Kruithof, Paul D., Steendam, Christi M.J., Boosman, René J., Mathijssen, Ron H.J., Tjan-Heijnen, Vivianne C.G., Driessen, Johanna H.M., Dursun, Safiye, Smit, Egbert F., Dingemans, Anne-Marie C., van Geel, Robin M.J.M., Croes, Sander, Hendriks, Lizza E.L.

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Rethinking the Application of Pemetrexed for Patients with Renal Impairment: A Pharmacokinetic Analysis von de Rouw, Nikki, Boosman, Rene J., Huitema, Alwin D. R., Hilbrands, Luuk B., Svensson, Elin M., Derijks, Hieronymus J., van den Heuvel, Michel M., Burger, David M., ter Heine, Rob

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