The Role of Vesicle Trafficking and Release in Oligodendrocyte Biology von Reiter, Cory R., Bongarzone, Ernesto R.

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Brainstem development requires galactosylceramidase and is critical for pathogenesis in a model of Krabbe disease von Weinstock, Nadav I., Kreher, Conlan, Favret, Jacob, Nguyen, Duc, Bongarzone, Ernesto R., Wrabetz, Lawrence, Feltri, M. Laura, Shin, Daesung

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Astrocyte Support for Oligodendrocyte Differentiation can be Conveyed via Extracellular Vesicles but Diminishes with Age von Willis, Cory M., Nicaise, Alexandra M., Bongarzone, Ernesto R., Givogri, Maria, Reiter, Cory R., Heintz, Olivia, Jellison, Evan R., Sutter, Pearl A., TeHennepe, Gregg, Ananda, Guruprasad, Vella, Anthony T., Crocker, Stephen J.

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Psychosine enhances the shedding of membrane microvesicles: Implications in demyelination in Krabbe's disease von D'Auria, Ludovic, Reiter, Cory, Ward, Emma, Moyano, Ana Lis, Marshall, Michael S, Nguyen, Duc, Scesa, Giuseppe, Hauck, Zane, van Breemen, Richard, Givogri, Maria I, Bongarzone, Ernesto R

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Beyond Krabbe's disease: The potential contribution of galactosylceramidase deficiency to neuronal vulnerability in late-onset synucleinopathies von Marshall, Michael S., Bongarzone, Ernesto R.

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Hyperglycemia increases SCO-spondin and Wnt5a secretion into the cerebrospinal fluid to regulate ependymal cell beating and glucose sensing von Nualart, Francisco, Cifuentes, Manuel, Ramírez, Eder, Martínez, Fernando, Barahona, María José, Ferrada, Luciano, Saldivia, Natalia, Bongarzone, Ernesto R, Thorens, Bernard, Salazar, Katterine

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Analysis of age-related changes in psychosine metabolism in the human brain von Marshall, Michael S, Jakubauskas, Benas, Bogue, Wil, Stoskute, Monika, Hauck, Zane, Rue, Emily, Nichols, Matthew, DiAntonio, Lisa L, van Breemen, Richard B, Kordower, Jeffrey H, Saavedra-Matiz, Carlos A, Bongarzone, Ernesto R

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Krabbe disease successfully treated via monotherapy of intrathecal gene therapy von Bradbury, Allison M., Bagel, Jessica H., Duc Nguyen, Lykken, Erik A., Salvador, Jill Pesayco, Jiang, Xuntian, Swain, Gary P., Assenmacher, Charles A., Hendricks, Ian J., Miyadera, Keiko, Hess, Rebecka S., Ostrager, Arielle, ODonnell, Patricia, Sands, Mark S., Ory, Daniel S., Shelton, G. Diane, Bongarzone, Ernesto R., Gray, Steven J., Vite, Charles H.

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Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction von Weinstock, Nadav I., Shin, Daesung, Dhimal, Narayan, Hong, Xinying, Irons, Eric E., Silvestri, Nicholas J., Reed, Chelsey B., Nguyen, Duc, Sampson, Oliver, Cheng, Yung-Chih, Lau, Joseph T.Y., Bongarzone, Ernesto R., Kofler, Julia, Escolar, Maria L., Gelb, Michael H., Wrabetz, Lawrence, Feltri, M. Laura

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Intrathecal administration of AAV/GALC vectors in 10-11-day-old twitcher mice improves survival and is enhanced by bone marrow transplant von Karumuthil-Melethil, Subha, Marshall, Michael S., Heindel, Clifford, Jakubauskas, Benas, Bongarzone, Ernesto R., Gray, Steven J.

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AAVrh10 Gene Therapy Ameliorates Central and Peripheral Nervous System Disease in Canine Globoid Cell Leukodystrophy (Krabbe Disease) von Bradbury, Allison M, Rafi, Mohammed A, Bagel, Jessica H, Brisson, Becky K, Marshall, Michael S, Pesayco Salvador, Jill, Jiang, Xuntain, Swain, Gary P, Prociuk, Maria L, ODonnell, Patricia A, Fitzgerald, Caitlin, Ory, Daniel S, Bongarzone, Ernesto R, Shelton, G Diane, Wenger, David A, Vite, Charles H

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Mass spectrometry imaging and LC/MS reveal decreased cerebellar phosphoinositides in Niemann-Pick type C1-null mice[S] von Pathmasiri, Koralege C., Pergande, Melissa R., Tobias, Fernando, Rebiai, Rima, Rosenhouse-Dantsker, Avia, Bongarzone, Ernesto R., Cologna, Stephanie M.

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Psychosine Accumulates in Membrane Microdomains in the Brain of Krabbe Patients, Disrupting the Raft Architecture von White, Adam B, Givogri, Maria I, Lopez-Rosas, Aurora, Cao, Hongmei, van Breemen, Richard, Thinakaran, Gopal, Bongarzone, Ernesto R

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Tumor-targeting cell-penetrating peptide, p28, for glioblastoma imaging and therapy von Mander, Sunam, Naffouje, Samer A., Gao, Jin, Li, Weiguo, Christov, Konstantin, Green, Albert, Bongarzone, Ernesto R., Das Gupta, Tapas K., Yamada, Tohru

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The Pathogenic Sphingolipid Psychosine is Secreted in Extracellular Vesicles in the Brain of a Mouse Model of Krabbe Disease von Reiter, Cory R., Rebiai, Rima, Kwak, Angelika, Marshall, Jeff, Wozniak, Dylan, Scesa, Giusepe, Nguyen, Duc, Rue, Emily, Pathmasiri, Koralege C., Pijewski, Robert, van Breemen, Richard, Cologna, Stephanie, Crocker, Stephen J., Givogri, M Irene, Bongarzone, Ernesto R

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α-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies von Abdelkarim, Hazem, Marshall, Michael S., Scesa, Giuseppe, Smith, Rachael A., Rue, Emily, Marshall, Jeffrey, Elackattu, Vince, Stoskute, Monika, Issa, Yazan, Santos, Marta, Nguyen, Duc, Hauck, Zane, van Breemen, Richard, Celej, Maria S., Gaponenko, Vadim, Bongarzone, Ernesto R.

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P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis von Sharp, Anthony J, Polak, Paul E, Simonini, Vittoria, Lin, Shao X, Richardson, Jill C, Bongarzone, Ernesto R, Feinstein, Douglas L

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AAV-Mediated GALC Gene Therapy Rescues Alpha-Synucleinopathy in the Spinal Cord of a Leukodystrophic Lysosomal Storage Disease Mouse Model von Marshall, Michael S., Issa, Yazan, Heller, Gregory, Nguyen, Duc, Bongarzone, Ernesto R.

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Inhibition of the IGF-1-PI3K-Akt-mTORC2 pathway in lipid rafts increases neuronal vulnerability in a genetic lysosomal glycosphingolipidosis von Sural-Fehr, Tuba, Singh, Harinder, Cantuti-Catelvetri, Ludovico, Zhu, Hongling, Marshall, Michael S, Rebiai, Rima, Jastrzebski, Martin J, Givogri, Maria I, Rasenick, Mark M, Bongarzone, Ernesto R

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Synaptic Function and Dysfunction in Lysosomal Storage Diseases von Rebiai, Rima, Givogri, Maria I., Gowrishankar, Swetha, Cologna, Stephania M., Alford, Simon T., Bongarzone, Ernesto R.

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