SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma von Bill, Kate Lynn J, Garnett, Jeannine, Meaux, Isabelle, Ma, XiaoYen, Creighton, Chad J, Bolshakov, Svetlana, Barriere, Cedric, Debussche, Laurent, Lazar, Alexander J, Prudner, Bethany C, Casadei, Lucia, Braggio, Danielle, Lopez, Gonzalo, Zewdu, Abbie, Bid, Hemant, Lev, Dina, Pollock, Raphael E

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Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies von Lahat, Guy, Zhu, Quan-Sheng, Huang, Kai-Lieh, Wang, Suizhao, Bolshakov, Svetlana, Liu, Jeffery, Torres, Keila, Langley, Robert R, Lazar, Alexander J, Hung, Mien Chie, Lev, Dina

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Activated MET Is a Molecular Prognosticator and Potential Therapeutic Target for Malignant Peripheral Nerve Sheath Tumors von TORRES, Keila E, ZHU, Quan-Sheng, BELOUSOV, Roman, SUIZHAU WANG, LAHAT, Guy, JUN LIU, HERNANDEZ, Belinda, LAZAR, Alexander J, LEV, Dina, BILL, Katelynn, LOPEZ, Gonzalo, GHADIMI, Markus P, XIANBIAO XIE, YOUNG, Eric D, JUEHUI LIU, NGUYEN, Theresa, BOLSHAKOV, Svetlana

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Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation von Hannay, Jonathan A F, Liu, Juehui, Zhu, Quan-Sheng, Bolshakov, Svetlana V, Li, Lan, Pisters, Peter W T, Lazar, Alexander J F, Yu, Dihua, Pollock, Raphael E, Lev, Dina

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Autophagic Survival in Resistance to Histone Deacetylase Inhibitors: Novel Strategies to Treat Malignant Peripheral Nerve Sheath Tumors von LOPEZ, Gonzalo, TORRES, Keila, MCCONKEY, David, LEV, Dina, JUEHUI LIU, HERNANDEZ, Belinda, YOUNG, Eric, BELOUSOV, Roman, BOLSHAKOV, Svetlana, LAZA, Alexander J, SLOPIS, John M, MCCUTCHEON, Ian E

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Genomic alterations in spontaneous and carcinogen-induced murine melanoma cell lines von MELNIKOVA, Vladislava O, BOLSHAKOV, Svetlana V, WALKER, Christopher, ANANTHASWAMY, Honnavara N

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The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma von Bill, Kate Lynn J, Garnett, Jeannine, Ma, Xiaoyan, May, Caitlin D, Bolshakov, Svetlana, Lazar, Alexander J, Lev, Dina C, Pollock, Raphael E

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An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors von Peng, Tingsheng, Zhang, Pingyu, Liu, Jeffery, Nguyen, Theresa, Bolshakov, Svetlana, Belousov, Roman, Young, Eric D, Wang, Xiaoke, Brewer, Kari, López-Terrada, Delores H, Oliveira, Andre M, Lazar, Alexander J, Lev, Dina

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Epithelioid Sarcoma and Unclassified Sarcoma with Epithelioid Features: Clinicopathological Variables, Molecular Markers, and a New Experimental Model von Sakharpe, Aniket, Lahat, Guy, Gulamhusein, Taher, Liu, Ping, Bolshakov, Svetlana, Nguyen, Theresa, Zhang, Pingyu, Belousov, Roman, Young, Eric, Xie, Xianbiao, Rao, Priya, Hornick, Jason L., Lazar, Alexander J., Pollock, Raphael E., Lev, Dina

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Wild-type p53 Inhibits Nuclear Factor-κB–Induced Matrix Metalloproteinase-9 Promoter Activation: Implications for Soft Tissue Sarcoma Growth and Metastasis von Liu, Jue, Zhan, Maocheng, Hannay, Jonathan A.F., Das, Parimal, Bolshakov, Svetlana V., Kotilingam, Dhanashankren, Yu, Dihua, Lazar, Alexander F., Pollock, Raphael E., Lev, Dina

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p53 Mutations in Human Aggressive and Nonaggressive Basal and Squamous Cell Carcinomas von BOLSHAKOV, Svetlana, WALKER, Christopher M, STROM, Sara S, SELVAN, Mano S, CLAYMAN, Gary L, EL-NAGGAR, Adel, LIPPMAN, Scott M, KRIPKE, Margaret L, ANANTHASWAMY, Honnavara N

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Combined Vascular Endothelial Growth Factor Receptor/Epidermal Growth Factor Receptor Blockade with Chemotherapy for Treatment of Local, Uterine, and Metastatic Soft Tissue Sarcoma von Ren, Wenhong, Korchin, Borys, Lahat, Guy, Wei, Caimiao, Bolshakov, Svetlana, Nguyen, Theresa, Merritt, William, Dicker, Adam, Lazar, Alexander, Sood, Anil, Pollock, Raphael E, Lev, Dina

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Mutant p53 is constitutively phosphorylated at Serine 15 in UV-induced mouse skin tumors: involvement of ERK1 2 MAP kinase von MELNIKOVA, Vladislava O, SANTAMARIA, Annette B, BOLSHAKOV, Svetlana V, ANANTHASWAMY, Honnavara N

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Specific Mutations in the β- Catenin Gene ( CTNNB1 ) Correlate with Local Recurrence in Sporadic Desmoid Tumors von Lazar, Alexander J.F, Tuvin, Daniel, Hajibashi, Shohrae, Habeeb, Sultan, Bolshakov, Svetlana, Mayordomo-Aranda, Empar, Warneke, Carla L, Lopez-Terrada, Dolores, Pollock, Raphael E, Lev, Dina

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Targeting the Notch pathway: A potential therapeutic approach for desmoid tumors von Shang, Hui, Braggio, Danielle, Lee, Ya‐Jung, Al Sannaa, Ghadah A., Creighton, Chad J., Bolshakov, Svetlana, Lazar, Alexander J. F., Lev, Dina, Pollock, Raphael E.

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CXCR4/CXCL12 Mediate Autocrine Cell- Cycle Progression in NF1-Associated Malignant Peripheral Nerve Sheath Tumors von Mo, Wei, Chen, Jian, Patel, Amish, Zhang, Liang, Chau, Vincent, Li, Yanjiao, Cho, Woosung, Lim, Kyun, Xu, Jing, Lazar, Alexander J., Creighton, Chad J., Bolshakov, Svetlana, McKay, Renée M., Lev, Dina, Le, Lu Q., Parada, Luis F.

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Pleomorphic liposarcoma von Ghadimi, Markus P., Liu, Ping, Peng, Tingsheng, Bolshakov, Svetlana, Young, Eric D., Torres, Keila E., Colombo, Chiara, Hoffman, Aviad, Broccoli, Dominique, Hornick, Jason L., Lazar, Alexander J., Pisters, Peter, Pollock, Raphael E., Lev, Dina

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Correction: SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma von Bill, Kate Lynn J, Garnett, Jeannine, Meaux, Isabelle, Ma, XiaoYen, Creighton, Chad J, Bolshakov, Svetlana, Barriere, Cedric, Debussche, Laurent, Lazar, Alexander J, Prudner, Bethany C, Casadei, Lucia, Braggio, Danielle, Lopez, Gonzalo, Zewdu, Abbie, Bid, Hemant, Dina, Lev, Pollock, Raphael E

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MiR-155 Is a Liposarcoma Oncogene That Targets Casein Kinase-1α and Enhances β-Catenin Signaling von PINGYU ZHANG, BILL, Katelynn, CREIGHTON, Chad J, ANDERSON, Matthew L, LAZAR, Alexander J, CALIN, George G, POLLOCK, Raphael E, LEV, Dina, JUEHUI LIU, YOUNG, Eric, TINGSHENG PENG, BOLSHAKOV, Svetlana, HOFFMAN, Aviad, YECHUN SONG, DEMICCO, Elizabeth G, LOPEZ TERRADA, Dolores

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Experimental models of undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumor von Bhalla, Angela D., Landers, Sharon M., Singh, Anand K., Landry, Jace P., Yeagley, Michelle G., Myerson, Gabryella S. B., Delgado-Baez, Cristian B., Dunnand, Stephanie, Nguyen, Theresa, Ma, Xiaoyan, Bolshakov, Svetlana, Menegaz, Brian A., Lamhamedi-Cherradi, Salah-Eddine, Mao, Xizeng, Song, Xingzhi, Lazar, Alexander J., McCutcheon, Ian E., Slopis, John M., Ludwig, Joseph A., Lev, Dina C., Rai, Kunal, Torres, Keila E.

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