The Pharmacology and Function of Receptors for Short-Chain Fatty Acids von Bolognini, Daniele, Tobin, Andrew B., Milligan, Graeme, Moss, Catherine E.

Volltext

Cannabidiol, a non-psychoactive cannabinoid compound, inhibits proliferation and invasion in U87-MG and T98G glioma cells through a multitarget effect von Solinas, Marta, Massi, Paola, Cinquina, Valentina, Valenti, Marta, Bolognini, Daniele, Gariboldi, Marzia, Monti, Elena, Rubino, Tiziana, Parolaro, Daniela

Volltext

Chemogenetics defines a short-chain fatty acid receptor gut-brain axis von Barki, Natasja, Bolognini, Daniele, Börjesson, Ulf, Jenkins, Laura, Riddell, John, Hughes, David I, Ulven, Trond, Hudson, Brian D, Ulven, Elisabeth Rexen, Dekker, Niek, Tobin, Andrew B, Milligan, Graeme

Volltext

Chemogenetics defines receptor-mediated functions of short chain free fatty acids von Bolognini, Daniele, Barki, Natasja, Butcher, Adrian J., Hudson, Brian D., Sergeev, Eugenia, Molloy, Colin, Moss, Catherine E., Bradley, Sophie J., Le Gouill, Christian, Bouvier, Michel, Tobin, Andrew B., Milligan, Graeme

Volltext

Phosphorylation bar-coding of free fatty acid receptor 2 is generated in a tissue-specific manner von Barki, Natasja, Jenkins, Laura, Marsango, Sara, Dedeo, Domonkos, Bolognini, Daniele, Dwomoh, Louis, Abdelmalik, Aisha M, Nilsen, Margaret, Stoffels, Manon, Nagel, Falko, Schulz, Stefan, Tobin, Andrew B, Milligan, Graeme

Volltext

A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional Bias von Bolognini, Daniele, Moss, Catherine E., Nilsson, Karolina, Petersson, Annika U., Donnelly, Iona, Sergeev, Eugenia, König, Gabriele M., Kostenis, Evi, Kurowska-Stolarska, Mariola, Miller, Ashley, Dekker, Niek, Tobin, Andrew B., Milligan, Graeme

Volltext

CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency von Smoum, Reem, Baraghithy, Saja, Chourasia, Mukesh, Breuer, Aviva, Mussai, Naama, Attar-Namdar, Malka, Kogan, Natalya M., Raphael, Bitya, Bolognini, Daniele, Cascio, Maria G., Marini, Pietro, Pertwee, Roger G., Shurki, Avital, Mechoulam, Raphael, Bab, Itai

Volltext

On-target and off-target effects of novel orthosteric and allosteric activators of GPR84 von Mancini, Sarah J., Mahmud, Zobaer Al, Jenkins, Laura, Bolognini, Daniele, Newman, Robert, Barnes, Matt, Edye, Michelle E., McMahon, Stephen B., Tobin, Andrew B., Milligan, Graeme

Volltext

A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias von Sergeev, Eugenia, Hansen, Anders Højgaard, Bolognini, Daniele, Kawakami, Kouki, Kishi, Takayuki, Aoki, Junken, Ulven, Trond, Inoue, Asuka, Hudson, Brian D., Milligan, Graeme

Volltext

Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 3. Synthesis, Structure−Affinity Relationships, and Pharmacological Characterization of 6-Substituted 4-Quinolone-3-carbo... von Pasquini, Serena, Ligresti, Alessia, Mugnaini, Claudia, Semeraro, Teresa, Cicione, Lavinia, De Rosa, Maria, Guida, Francesca, Luongo, Livio, De Chiaro, Maria, Cascio, Maria Grazia, Bolognini, Daniele, Marini, Pietro, Pertwee, Roger, Maione, Sabatino, Marzo, Vincenzo Di, Corelli, Federico

Volltext

Loss of Huntingtin Function Complemented by Small Molecules Acting as Repressor Element 1/Neuron Restrictive Silencer Element Silencer Modulators von Rigamonti, Dorotea, Bolognini, Daniele, Mutti, Cesare, Zuccato, Chiara, Tartari, Marzia, Sola, Francesco, Valenza, Marta, Kazantsev, Aleksey G., Cattaneo, Elena

Volltext

Treatment of Active Crohn’s Disease With an Ordinary Food-based Diet That Replicates Exclusive Enteral Nutrition von Svolos, Vaios, Hansen, Richard, Nichols, Ben, Quince, Christopher, Ijaz, Umer Z., Papadopoulou, Rodanthi T., Edwards, Christine A., Watson, David, Alghamdi, Adel, Brejnrod, Asker, Ansalone, Cecilia, Duncan, Hazel, Gervais, Lisa, Tayler, Rachel, Salmond, Jonathan, Bolognini, Daniele, Klopfleisch, Robert, Gaya, Daniel R., Milling, Simon, Russell, Richard K., Gerasimidis, Konstantinos

Volltext

Adaptation of NS cells growth and differentiation to high-throughput screening-compatible plates von Garavaglia, Alessia, Moiana, Alessia, Camnasio, Stefano, Bolognini, Daniele, Papait, Roberto, Rigamonti, Dorotea, Cattaneo, Elena

Volltext

P273 Chemogenetic analysis of how receptors for short chain fatty acids regulate the gut-brain axis von Barki, Natasja, Bolognini, Daniele, Jenkins, Laura, Hudson, Brian, Tobin, Andrew, Milligan, Graeme

Volltext

Metabolic and inflammatory functions of short-chain fatty acid receptors von Bolognini, Daniele, Dedeo, Domonkos, Milligan, Graeme

Volltext

Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties von Hansen, Anders Højgaard, Sergeev, Eugenia, Bolognini, Daniele, Sprenger, Richard R, Ekberg, Jeppe Hvidtfeldt, Ejsing, Christer S, McKenzie, Christine J, Rexen Ulven, Elisabeth, Milligan, Graeme, Ulven, Trond

Volltext

CB1 Receptor Allosteric Modulators Display Both Agonist and Signaling Pathway Specificity von Baillie, Gemma L., Horswill, James G., Anavi-Goffer, Sharon, Reggio, Patricia H., Bolognini, Daniele, Abood, Mary E., McAllister, Sean, Strange, Phillip G., Stephens, Gary J., Pertwee, Roger G., Ross, Ruth A.

Volltext

Phosphorylation bar-coding of free fatty acid receptor 2 is generated in a tissue-specific manner von Barki, Natasja, Jenkins, Laura, Marsango, Sara, Dedeo, Domonkos, Bolognini, Daniele, Dwomoh, Louis, Abdelmalik, Aisha M, Nilsen, Margaret, Stoffels, Manon, Nagel, Falko, Schulz, Stefan, Tobin, Andrew B, Milligan, Graeme

Volltext

AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor von Bolognini, Daniele, Cascio, Maria Grazia, Parolaro, Daniela, Pertwee, Roger G

Volltext

AM630 behaves as a protean ligand at the human cannabinoid CB 2 receptor von Bolognini, Daniele, Cascio, Maria Grazia, Parolaro, Daniela, Pertwee, Roger G

Volltext