Synthesis of N‑Substituted 3‑Amino-2-pyridones von Bolduc, Philippe N., Pfaffenbach, Magnus, Blasczak, Vanna D., Mathieu, Steven R., Peterson, Emily A.

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Carbon quaternization of redox active esters and olefins by decarboxylative coupling von Gan, Xu-Cheng, Zhang, Benxiang, Dao, Nathan, Bi, Cheng, Pokle, Maithili, Kan, Liyan, Collins, Michael R, Tyrol, Chet C, Bolduc, Philippe N, Nicastri, Michael, Kawamata, Yu, Baran, Phil S, Shenvi, Ryan

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Overcoming Limitations in Decarboxylative Arylation via Ag–Ni Electrocatalysis von Palkowitz, Maximilian D., Laudadio, Gabriele, Kolb, Simon, Choi, Jin, Oderinde, Martins S., Ewing, Tamara El-Hayek, Bolduc, Philippe N., Chen, TeYu, Zhang, Hao, Cheng, Peter T. W., Zhang, Benxiang, Mandler, Michael D., Blasczak, Vanna D., Richter, Jeremy M., Collins, Michael R., Schioldager, Ryan L., Bravo, Martin, Dhar, T. G. Murali, Vokits, Benjamin, Zhu, Yeheng, Echeverria, Pierre-Georges, Poss, Michael A., Shaw, Scott A., Clementson, Sebastian, Petersen, Nadia Nasser, Mykhailiuk, Pavel K., Baran, Phil S.

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The Discovery of 7‑Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)‑N‑(6-methylpyrazolo[1,5‑a]pyrimidin-3-yl)imidazo[1,2‑a]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selec... von Evans, Ryan, Bolduc, Philippe N., Pfaffenbach, Magnus, Gao, Fang, May-Dracka, Tricia, Fang, Terry, Hopkins, Brian T., Chodaparambil, Jayanth V, Henry, Kate L., Li, Pei, Metrick, Claire, Nelson, Ashley, Trapa, Patrick, Thomas, Ankur, Burkly, Linda, Peterson, Emily A.

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Discovery of BIO-8169A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation von Pfaffenbach, Magnus, Bolduc, Philippe N., Xin, Zhili, Gao, Fang, Evans, Ryan, Fang, Terry, Chodaparambil, Jayanth V., Henry, Kate L., Li, Pei, Mathieu, Steven, Metrick, Claire, Vera Rebollar, Jorge A., Gu, Rong-Fang, Mccarl, Christie-Ann, Silbereis, John, Peterson, Emily A.

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Synthesis of Unnatural Amino Acids via Ni/Ag Electrocatalytic Cross-Coupling von Laudadio, Gabriele, Neigenfind, Philipp, Chebolu, Rajesh, Blasczak, Vanna D., Maddirala, Shambabu Joseph, Palkowitz, Maximilian D., Bolduc, Philippe N., Nicastri, Michael C., Puthukanoori, Ravi Kumar, Paraselli, Bheema Rao, Baran, Phil S.

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Complex molecule synthesis by electrocatalytic decarboxylative cross-coupling von Zhang, Benxiang, He, Jiayan, Gao, Yang, Levy, Laura, Oderinde, Martins S., Palkowitz, Maximilian D., Dhar, T. G. Murali, Mandler, Michael D., Collins, Michael R., Schmitt, Daniel C., Bolduc, Philippe N., Chen, TeYu, Clementson, Sebastian, Petersen, Nadia Nasser, Laudadio, Gabriele, Bi, Cheng, Kawamata, Yu, Baran, Phil S.

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Nickel‐Electrocatalytic Decarboxylative Arylation to Access Quaternary Centers von Laudadio, Gabriele, Neigenfind, Philipp, Péter, Áron, Rubel, Camille Z., Emmanuel, Megan A., Oderinde, Martins S., Ewing, Tamara El‐Hayek, Palkowitz, Maximilian D., Sloane, Jack L., Gillman, Kevin W., Ridge, Daniel, Mandler, Michael D., Bolduc, Philippe N., Nicastri, Michael C., Zhang, Benxiang, Clementson, Sebastian, Petersen, Nadia Nasser, Martín‐Gago, Pablo, Mykhailiuk, Pavel, Engle, Keary M., Baran, Phil S.

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A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors von Bolduc, Philippe N., Pfaffenbach, Magnus, Evans, Ryan, Xin, Zhili, Henry, Kate L., Gao, Fang, Fang, Terry, Silbereis, John, Vera Rebollar, Jorge, Li, Pei, Chodaparambil, Jayanth V, Metrick, Claire, Peterson, Emily A.

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Nickel‐Electrocatalytic Decarboxylative Arylation to Access Quaternary Centers von Laudadio, Gabriele, Neigenfind, Philipp, Péter, Áron, Rubel, Camille Z., Emmanuel, Megan A., Oderinde, Martins S., Ewing, Tamara El‐Hayek, Palkowitz, Maximilian D., Sloane, Jack L., Gillman, Kevin W., Ridge, Daniel, Mandler, Michael D., Bolduc, Philippe N., Nicastri, Michael C., Zhang, Benxiang, Clementson, Sebastian, Petersen, Nadia Nasser, Martín‐Gago, Pablo, Mykhailiuk, Pavel, Engle, Keary M., Baran, Phil S.

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Endovascular repair of traumatic rupture of the aortic isthmus: Midterm results von Marcheix, Bertrand, Dambrin, Camille, Bolduc, Jean-Philippe, Arnaud, Catherine, Hollington, Lucy, Cron, Christophe, Mugniot, Antoine, Soula, Philippe, Bennaceur, Mehdi, Chabbert, Valérie, Otal, Philippe, Cérène, Alain, Rousseau, Hervé

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Efficient Macrocyclization Achieved via Conformational Control Using Intermolecular Noncovalent π-Cation/Arene Interactions von Bolduc, Philippe, Jacques, Alexandre, Collins, Shawn K

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Discovery of [18F]F-687-TCO: An Optimized Tracer for Pretargeted PET Imaging in the CNS von Cook, Brendon, Pickel, Thomas, Jiang, Di, Bolduc, Philippe, Nag, Sangram, Tang, Sac-Pham, Nasr, Khaled, Boscutti, Giulia, Plisson, Christophe, Morén, Anton, Ochniewicz, Piotr, Halldin, Christer, Peterson, Emily, Martarello, Laurent, Kaliszczak, Maciej

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A small-molecule inhibitor of C5 complement protein von Jendza, Keith, Kato, Mitsunori, Salcius, Michael, Srinivas, Honnappa, De Erkenez, Andrea, Nguyen, Anh, McLaughlin, Doug, Be, Celine, Wiesmann, Christian, Murphy, Jason, Bolduc, Philippe, Mogi, Muneto, Duca, Jose, Namil, Abdel, Capparelli, Michael, Darsigny, Veronique, Meredith, Erik, Tichkule, Ritesh, Ferrara, Luciana, Heyder, Jessica, Liu, Fang, Horton, Patricia A., Romanowski, Michael J., Schirle, Markus, Mainolfi, Nello, Anderson, Karen, Michaud, Gregory A.

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Midterm results of endovascular treatment of atherosclerotic aneurysms of the descending thoracic aorta von Marcheix, Bertrand, Dambrin, Camille, Bolduc, Jean-Philippe, Arnaud, Catherine, Cron, Christophe, Hollington, Lucy, Mugniot, Antoine, Soula, Philippe, Bennaceur, Mehdi, Chabbert, Valérie, Massabuau, Pierre, Otal, Philippe, Cérène, Alain, Rousseau, Hervé

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The Discovery of ( S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1 H-inden-4-yl)pyridin-2-yl)-5-methyl-1 H-pyrazole-4-carboxylic Acid, a... von Ehara, Takeru, Adams, Christopher M, Bevan, Doug, Ji, Nan, Meredith, Erik L, Belanger, David B, Powers, James, Kato, Mitsunori, Solovay, Catherine, Liu, Donglei, Capparelli, Michael, Bolduc, Philippe, Grob, Jonathan E, Daniels, Matthew H, Ferrara, Luciana, Yang, Louis, Li, Byron, Towler, Christopher S, Stacy, Rebecca C, Prasanna, Ganesh, Mogi, Muneto

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Functional popliteal artery entrapment syndrome (FPAES) treatment with incobotulinumtoxinA: 3 successful clinical cases von Petitclerc, Marc, Bolduc, Jean-Philippe, Drolet, Pascale

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Clindamycin/Primaquine Versus Trimethoprim-Sulfamethoxazole as Primary Therapy for Pneumocystis carinii Pneumonia in AIDS: A Randomized, Double-Blind Pilot Trial von Toma, Emil, Fournier, Sylvie, Dumont, Marc, Bolduc, Philippe, Deschamps, Helene

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The Discovery of (S)‑1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro‑1H‑inden-4-yl)pyridin-2-yl)-5-methyl‑1H‑pyrazole-4-carboxylic Acid, a So... von Ehara, Takeru, Adams, Christopher M, Bevan, Doug, Ji, Nan, Meredith, Erik L, Belanger, David B, Powers, James, Kato, Mitsunori, Solovay, Catherine, Liu, Donglei, Capparelli, Michael, Bolduc, Philippe, Grob, Jonathan E, Daniels, Matthew H, Ferrara, Luciana, Yang, Louis, Li, Byron, Towler, Christopher S, Stacy, Rebecca C, Prasanna, Ganesh, Mogi, Muneto

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IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS IRAK4 INHIBITORS AND THEIR USE IN THE TREATMENT OF DISEASE von Evans, Ryan, Peterson, Emily Anne, Gao, Fang, Pfaffenbach, Magnus, Xin, Zhili, Bolduc, Philippe

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