PARP Inhibitors: Clinical Relevance, Mechanisms of Action and Tumor Resistance von Rose, Maddison, Burgess, Joshua T., O’Byrne, Kenneth, Richard, Derek J., Bolderson, Emma

Volltext

Nucleophosmin: from structure and function to disease development von Box, Joseph K, Paquet, Nicolas, Adams, Mark N, Boucher, Didier, Bolderson, Emma, O'Byrne, Kenneth J, Richard, Derek J

Volltext

hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage von Boucher, Didier, Kariawasam, Ruvini, Burgess, Joshua, Gimenez, Adrian, Ocampo, Tristan E., Ferguson, Blake, Naqi, Ali, Walker, Graeme J., Bolderson, Emma, Gamsjaeger, Roland, O’Byrne, Kenneth J., Cubeddu, Liza, Khanna, Kum Kum, Richard, Derek J.

Volltext

Recent Advances in Cancer Therapy Targeting Proteins Involved in DNA Double-Strand Break Repair von BOLDERSON, Emma, RICHARD, Derek J, ZHOU, Bin-Bing S, KHANNA, Kum Kum

Volltext

Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage von Bolderson, Emma, Burgess, Joshua T., Li, Jun, Gandhi, Neha S., Boucher, Didier, Croft, Laura V., Beard, Samuel, Plowman, Jennifer J., Suraweera, Amila, Adams, Mark N., Naqi, Ali, Zhang, Shu-Dong, Sinclair, David A., O’Byrne, Kenneth J., Richard, Derek J.

Volltext

The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair von Sobanski, Thais, Suraweera, Amila, Burgess, Joshua T., Richard, Iain, Cheong, Chee Man, Dave, Keyur, Rose, Maddison, Adams, Mark N., O’Byrne, Kenneth J., Richard, Derek J., Bolderson, Emma

Volltext

Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions von Tomimatsu, Nozomi, Mukherjee, Bipasha, Deland, Katherine, Kurimasa, Akihiro, Bolderson, Emma, Khanna, Kum Kum, Burma, Sandeep

Volltext

SASH1 is a prognostic indicator and potential therapeutic target in non-small cell lung cancer von Burgess, Joshua T., Bolderson, Emma, Adams, Mark N., Duijf, Pascal H. G., Zhang, Shu-Dong, Gray, Steven G., Wright, Gavin, Richard, Derek J., O’Byrne, Kenneth J.

Volltext

Cell Metabolism and DNA Repair Pathways: Implications for Cancer Therapy von Sobanski, Thais, Rose, Maddison, Suraweera, Amila, O'Byrne, Kenneth, Richard, Derek J, Bolderson, Emma

Volltext

The Therapeutic Potential of DNA Damage Repair Pathways and Genomic Stability in Lung Cancer von Burgess, Joshua T., Rose, Maddison, Boucher, Didier, Plowman, Jennifer, Molloy, Christopher, Fisher, Mark, O'Leary, Connor, Richard, Derek J., O'Byrne, Kenneth J., Bolderson, Emma

Volltext

Beyond PARP1: The Potential of Other Members of the Poly (ADP-Ribose) Polymerase Family in DNA Repair and Cancer Therapeutics von Richard, Iain A, Burgess, Joshua T, O'Byrne, Kenneth J, Bolderson, Emma

Volltext

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks von Bolderson, Emma, Tomimatsu, Nozomi, Richard, Derek J, Boucher, Didier, Kumar, Rakesh, Pandita, Tej K, Burma, Sandeep, Khanna, Kum Kum

Volltext

Tumor Hypoxia Drives Genomic Instability von Tang, Ming, Bolderson, Emma, O'Byrne, Kenneth J, Richard, Derek J

Volltext

The expression and role of the Lem-D proteins Ankle2, Emerin, Lemd2, and TMPO in triple-negative breast cancer cell growth von Rose, Maddison, Burgess, Joshua T, Cheong, Chee Man, Adams, Mark N, Shahrouzi, Parastoo, O'Byrne, Kenneth J, Richard, Derek J, Bolderson, Emma

Volltext

Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis von Richard, Derek J., Bolderson, Emma, Khanna, Kum Kum

Volltext

Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising von Jekimovs, Christian, Bolderson, Emma, Suraweera, Amila, Adams, Mark, O'Byrne, Kenneth J, Richard, Derek J

Volltext

hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway von Paquet, Nicolas, Adams, Mark N, Leong, Vincent, Ashton, Nicholas W, Touma, Christine, Gamsjaeger, Roland, Cubeddu, Liza, Beard, Sam, Burgess, Joshua T, Bolderson, Emma, O'Byrne, Ken J, Richard, Derek J

Volltext

Human single-stranded DNA binding proteins are essential for maintaining genomic stability von Ashton, Nicholas W, Bolderson, Emma, Cubeddu, Liza, O'Byrne, Kenneth J, Richard, Derek J

Volltext

Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy von Kildey, Katrina, Gandhi, Neha S., Sahin, Katherine B., Shah, Esha T., Boittier, Eric, Duijf, Pascal H. G., Molloy, Christopher, Burgess, Joshua T., Beard, Sam, Bolderson, Emma, Suraweera, Amila, Richard, Derek J., O’Byrne, Kenneth J., Adams, Mark N.

Volltext

hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage Response von Li, Yongjiang, Bolderson, Emma, Kumar, Rakesh, Muniandy, Parameswary A., Xue, Yutong, Richard, Derek J., Seidman, Michael, Pandita, Tej K., Khanna, Kum Kum, Wang, Weidong

Volltext