Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications von Kovacikova, Lucia, Prnova, Marta Soltesova, Majekova, Magdalena, Bohac, Andrej, Karasu, Cimen, Stefek, Milan

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Cu(II) mediated oxidation of cemtirestat yields its disulfide under physiological conditions in vitro von Bodo, Pavol, Kovacikova, Lucia, Bohac, Andrej, Stefek, Milan

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Synthesis of glycolysis inhibitor (E)-3-(pyridin-3-yl)-1-(pyridin-4-yl)prop-2-en-1-one (3PO) and its inhibition of HUVEC proliferation alone or in a combination with the multi-kina... von Murár, Miroslav, Horvathová, Jana, Moravčík, Roman, Addová, Gabriela, Zeman, Michal, Boháč, Andrej

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Synthesis of Glycolysis Inhibitor PFK15 and Its Synergistic Action with an Approved Multikinase Antiangiogenic Drug on Human Endothelial Cell Migration and Proliferation von Zlacká, Jana, Murár, Miroslav, Addová, Gabriela, Moravčík, Roman, Boháč, Andrej, Zeman, Michal

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Inhibition of Glycolysis Suppresses Cell Proliferation and Tumor Progression In Vivo: Perspectives for Chronotherapy von Horváthová, Jana, Moravčík, Roman, Matúšková, Miroslava, Šišovský, Vladimír, Boháč, Andrej, Zeman, Michal

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Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Sele... von Hlaváč, Matúš, Kováčiková, Lucia, Prnová, Marta Šoltésová, Šramel, Peter, Addová, Gabriela, Májeková, Magdaléna, Hanquet, Gilles, Boháč, Andrej, Štefek, Milan

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Convenient synthesis and unusual reactivity of 2-oxo-2H,5H-pyrano[3,2-c]chromenes von Lácová, Margita, Stankovičová, Henrieta, Boháč, Andrej, Kotzianová, Bibiána

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Novel substituted N-benzyl(oxotriazinoindole) inhibitors of aldose reductase exploiting ALR2 unoccupied interactive pocket von Hlaváč, Matúš, Kováčiková, Lucia, Šoltésová Prnová, Marta, Addová, Gabriela, Hanquet, Gilles, Štefek, Milan, Boháč, Andrej

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Selectivity of N(2)-substituted oxotriazinoindole aldose reductase inhibitors is determined by the interaction pattern with Pro301-Arg312 loop of aldehyde reductase von Kováčiková, Lucia, Gaikwad, Sunil, Almášiová, Kristína, Almássy, Ambroz, Addová, Gabriela, Májeková, Magdaléna, Hanquet, Gilles, Dobričić, Vladimir, Boháč, Andrej, Štefek, Milan

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Novel CLK1 inhibitors based on N-aryloxazol-2-amine skeleton - A possible way to dual VEGFR2 TK/CLK ligands von Murár, Miroslav, Dobiaš, Juraj, Šramel, Peter, Addová, Gabriela, Hanquet, Gilles, Boháč, Andrej

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Molecular structure, pKa, lipophilicity, solubility, absorption, polar surface area, and blood brain barrier penetration of some antiangiogenic agents von Remko, Milan, Boháč, Andrej, Kováčiková, Lucia

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A development of chimeric VEGFR2 TK inhibitor based on two ligand conformers from PDB: 1Y6A complex – Medicinal chemistry consequences of a TKs analysis von Lintnerová, Lucia, García-Caballero, Melissa, Gregáň, Fridrich, Melicherčík, Milan, Quesada, Ana R., Dobiaš, Juraj, Lác, Ján, Sališová, Marta, Boháč, Andrej

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Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase von Kimani, Stanley G, Kumar, Sushil, Davra, Viralkumar, Chang, Yun-Juan, Kasikara, Canan, Geng, Ke, Tsou, Wen-I, Wang, Shenyan, Hoque, Mainul, Boháč, Andrej, Lewis-Antes, Anita, De Lorenzo, Mariana S, Kotenko, Sergei V, Birge, Raymond B

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Ynamide Click chemistry in development of triazole VEGFR2 TK modulators von Vojtičková, Margaréta, Dobiaš, Juraj, Hanquet, Gilles, Addová, Gabriela, Cetin-Atalay, Rengul, Yildirim, Deniz Cansen, Boháč, Andrej

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Synthesis and antibacterial activity of furo[3,2-b]pyrrole derivatives von Zemanová, Ivana, Gašparová, Renata, Boháč, Andrej, Maliar, Tibor, Kraic, Filip, Addová, Gabriela

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2H-Pyrano[3,2-c]quinolin-2-ones: their convenient synthesis and selected reactions von Čakurda, Matúš, Koiš, Pavol, Addová, Gabriela, Lácová, Margita, Boháč, Andrej

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A novel and efficient synthesis of 3-aryl-5-(2-hydroxybenzoyl)pyridin-2(1H)-ones by re-cyclization of N-(oxopyranochromenyl)acetamides and their antineoplastic screening von Lácová, Margita, Čakurda, Matúš, Koiš, Pavol, Addová, Gabriela, Boháč, Andrej

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Synergic effects of inhibition of glycolysis and multikinase receptor signalling on proliferation and migration of endothelial cells von Horváthová, Jana, Moravčík, Roman, Boháč, Andrej, Zeman, Michal

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Medicinal chemistry: an effect of a desolvation penalty of an amide group in the development of kinase inhibitors von Dobiaš, Juraj, Ondruš, Marek, Hlaváč, Matúš, Murár, Miroslav, Kóňa, Juraj, Addová, Gabriela, Boháč, Andrej

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Synthesis of 5-(ethylsulfonyl)-2-methoxyaniline: An important pharmacological fragment of VEGFR2 and other inhibitors von Murár, Miroslav, Addová, Gabriela, Boháč, Andrej

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