Troglitazone-Induced Hepatic Necrosis in an Animal Model of Silent Genetic Mitochondrial Abnormalities von Ong, Michie M.K., Latchoumycandane, Calivarathan, Boelsterli, Urs A.

Volltext

Diclofenac Covalent Protein Binding Is Dependent on Acyl Glucuronide Formation and Is Inversely Related to P450-Mediated Acute Cell Injury in Cultured Rat Hepatocytes von Kretzrommel, A., Boelsterli, U.A.

Volltext

Acetaminophen hepatotoxicity in tumor necrosis factor/lymphotoxin‐α gene knockout mice von Boess, Franziska, Bopst, Martin, Althaus, Roland, Polsky, Stacey, Cohen, Steven D., Eugster, Hans‐Pietro, Boelsterli, Urs A.

Volltext

Effects of cocaine and its oxidative metabolites on mitochondrial respiration and generation of reactive oxygen species von Boess, Franziska, Ndikum-Moffor, Florence M, Boelsterli, Urs A, Roberts, Stephen M

Volltext

Nimesulide and hepatic adverse effects: Roles of reactive metabolites and host factors von Boelsterli, U A

Volltext

Mechanisms of NSAID-induced hepatotoxicity: Focus on nimesulide von BOELSTERLI, Urs A

Volltext

Selective protein adducts to membrane proteins in cultured rat hepatocytes exposed to diclofenac: radiochemical and immunochemical analysis von KRETZ-ROMMEL, A, BOELSTERLI, U. A

Volltext

Mechanisms of pathogenesis in drug hepatotoxicity putting the stress on mitochondria von Jones, Dean P, Lemasters, John J, Han, Derick, Boelsterli, Urs A, Kaplowitz, Neil

Volltext

Antioxidant and cytoprotective properties of D-tagatose in cultured murine hepatocytes von PATERNA, J. C, BOESS, F, STÄUBLI, A, BOELSTERLI, U. A

Volltext

Cytotoxic activity of T cells and non‐T cells from diclofenac‐immunized mice against cultured syngeneic hepatocytes exposed to diclofenac von Kretz‐Rommel, Anke, Boelsterli, Urs A.

Volltext

Two-dimensional database of mouse liver proteins: Changes in hepatic protein levels following treatment with acetaminophen or its nontoxic regioisomer 3-acetamidophenol von Fountoulakis, Michael, Berndt, Peter, Boelsterli, Urs A., Crameri, Flavio, Winter, Michael, Albertini, Silvio, Suter, Laura

Volltext

CYP 450 enzyme induction by chronic oral musk xylene in adult and developing rats von Suter-Eichenberger, R, Boelsterli, U.A, Conscience-Egli, M, Lichtensteiger, W, Schlumpf, M

Volltext

Healthy animals and animal models of human disease(s) in safety assessment of human pharmaceuticals, including therapeutic antibodies von Dixit, Rakesh, Boelsterli, Urs A.

Volltext

CYP 450 enzyme induction by chronic oral musk xylene in adult and developing rats von Suter-Eichenberger, R, Boelsterli, U.A, Conscience-Egli, M, Lichtensteiger, W, Schlumpf, M

Volltext

Selective Protein Adduct Formation of Diclofenac Glucuronide Is Critically Dependent on the Rat Canalicular Conjugate Export Pump (Mrp2) von Seitz, Sven, Kretz-Rommel, Anke, Oude Elferink, Ronald P. J, Boelsterli, Urs A

Volltext

Synthesis and Biodistribution of a Short Nonionic Oligonucleotide Analogue in Mouse with a Potential to Mimic Peptides von Eschgfäller, Bernd, König, Marcel, Boess, Franziska, Boelsterli, Urs A, Benner, Steven A

Volltext

Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity von Kashimshetty, Rohini, Desai, Varsha G., Kale, Vijay M., Lee, Taewon, Moland, Carrie L., Branham, William S., New, Lee S., Chan, Eric C.Y., Younis, Husam, Boelsterli, Urs A.

Volltext

Reactive oxygen species and non-peroxidative mechanisms of cocaine-induced cytotoxicity in rat hepatocyte cultures von Göldlin, Christian R., Boelsterli, Urs A.

Volltext

The heterozygous Sod2 super(+) super(/) super(-) mouse: modeling the mitochondrial role in drug toxicity von Boelsterli, U A, Hsiao, CJJ

Volltext

Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte inju... von Siu, Woen Ping, Pun, Pamela Boon Li, Latchoumycandane, Calivarathan, Boelsterli, Urs A.

Volltext