Consistent set of interfaces derived from a business object model von OEHLER UWE, BIJJALA RAVISHANKAR, REISERT CORINNE, LINDEMANN THIEMO, ESAU ANDREAS, SEIBEL ANDREAS, LANGENDOERFER BLEICKARD, THIENEL HANS-PETER, ULASENKA SIARHEI, SCHUETTE MARK T, ZUMBACH KLAUS, WALTEMATHE ROLF, RAUSSE CHRISTOF, KOUJALAGI MADHAVI, WELLENHOFER GEROLD, REBHOLZ SVETLANA, HENKES DIETMAR, SINGH ABHINAVA P, LEINENKUGEL CORNEL, WOLLE JENS-MARTIN, WADEWITZ PETER, SCHNEIDER THOMAS, HISSLER CHRISTIAN, HAMBRECHT KERSTIN, HERBST UDO, SCHICK EBERHARD, VIZHANYO ANDOR, HUBER-BUSCHBECK ANDREAS, WAGENKNECHT RALF, DOENIG SUSANNE, YENGOTI CHANDRAMOHAN R, BOEHM STEFAN C, PLUDER CARSTEN, HOLLBERG JUERGEN, POULIN JEROME, MASOUMEH MOGHADDAM, PANWAR HARSH, SANTOSO BUDI, RAJAMOHAN DEVASENA, EGEN GERD, SZIGETI GABOR, V SHANKAR, WERNER CHRISTIAN, ARLT GERGOR, VONDERHEID OLIVER, CHAKRABARTI RANA, VARGA TAMAS, THEISSEN HEIKO, ACHIMAN SHIRY, DOPPENSCHMIDT ASTRID

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Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells von Scholl, Claudia, Fröhling, Stefan, Dunn, Ian F., Schinzel, Anna C., Barbie, David A., Kim, So Young, Silver, Serena J., Tamayo, Pablo, Wadlow, Raymond C., Ramaswamy, Sridhar, Döhner, Konstanze, Bullinger, Lars, Sandy, Peter, Boehm, Jesse S., Root, David E., Jacks, Tyler, Hahn, William C., Gilliland, D. Gary

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Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure von Packer, Milton, Anker, Stefan D, Butler, Javed, Filippatos, Gerasimos, Pocock, Stuart J, Carson, Peter, Januzzi, James, Verma, Subodh, Tsutsui, Hiroyuki, Brueckmann, Martina, Jamal, Waheed, Kimura, Karen, Schnee, Janet, Zeller, Cordula, Cotton, Daniel, Bocchi, Edimar, Böhm, Michael, Choi, Dong-Ju, Chopra, Vijay, Chuquiure, Eduardo, Giannetti, Nadia, Janssens, Stefan, Zhang, Jian, Gonzalez Juanatey, Jose R, Kaul, Sanjay, Brunner-La Rocca, Hans-Peter, Merkely, Bela, Nicholls, Stephen J, Perrone, Sergio, Pina, Ileana, Ponikowski, Piotr, Sattar, Naveed, Senni, Michele, Seronde, Marie-France, Spinar, Jindrich, Squire, Iain, Taddei, Stefano, Wanner, Christoph, Zannad, Faiez

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Land use intensification alters ecosystem multifunctionality via loss of biodiversity and changes to functional composition von Allan, Eric, Manning, Pete, Alt, Fabian, Binkenstein, Julia, Blaser, Stefan, Blüthgen, Nico, Böhm, Stefan, Grassein, Fabrice, Hölzel, Norbert, Klaus, Valentin H, Kleinebecker, Till, Morris, E. Kathryn, Oelmann, Yvonne, Prati, Daniel, Renner, Swen C, Rillig, Matthias C, Schaefer, Martin, Schloter, Michael, Schmitt, Barbara, Schöning, Ingo, Schrumpf, Marion, Solly, Emily, Sorkau, Elisabeth, Steckel, Juliane, Steffen‐Dewenter, Ingolf, Stempfhuber, Barbara, Tschapka, Marco, Weiner, Christiane N, Weisser, Wolfgang W, Werner, Michael, Westphal, Catrin, Wilcke, Wolfgang, Fischer, Markus, Knops, Johannes

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Empagliflozin in Heart Failure with a Preserved Ejection Fraction von Anker, Stefan D, Butler, Javed, Filippatos, Gerasimos, Ferreira, João P, Bocchi, Edimar, Böhm, Michael, Brunner–La Rocca, Hans-Peter, Choi, Dong-Ju, Chopra, Vijay, Chuquiure-Valenzuela, Eduardo, Giannetti, Nadia, Gomez-Mesa, Juan Esteban, Janssens, Stefan, Januzzi, James L, Gonzalez-Juanatey, Jose R, Merkely, Bela, Nicholls, Stephen J, Perrone, Sergio V, Piña, Ileana L, Ponikowski, Piotr, Senni, Michele, Sim, David, Spinar, Jindrich, Squire, Iain, Taddei, Stefano, Tsutsui, Hiroyuki, Verma, Subodh, Vinereanu, Dragos, Zhang, Jian, Carson, Peter, Lam, Carolyn Su Ping, Marx, Nikolaus, Zeller, Cordula, Sattar, Naveed, Jamal, Waheed, Schnaidt, Sven, Schnee, Janet M, Brueckmann, Martina, Pocock, Stuart J, Zannad, Faiez, Packer, Milton

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The impact of even-aged and uneven-aged forest management on regional biodiversity of multiple taxa in European beech forests von Schall, Peter, Gossner, Martin M., Heinrichs, Steffi, Fischer, Markus, Boch, Steffen, Prati, Daniel, Jung, Kirsten, Baumgartner, Vanessa, Blaser, Stefan, Böhm, Stefan, Buscot, François, Daniel, Rolf, Goldmann, Kezia, Kaiser, Kristin, Kahl, Tiemo, Lange, Markus, Müller, Jörg, Overmann, Jörg, Renner, Swen C., Wemheuer, Bernd, Schulze, Ernst-Detlef, Sikorski, Johannes, Tschapka, Marco, Türke, Manfred, Weisser, Wolfgang W., Wubet, Tesfaye, Ammer, Christian

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2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failu... von McDonagh, Theresa A, Metra, Marco, Adamo, Marianna, Gardner, Roy S, Baumbach, Andreas, Böhm, Michael, Burri, Haran, Butler, Javed, Čelutkienė, Jelena, Chioncel, Ovidiu, Cleland, John G F, Coats, Andrew J S, Crespo-Leiro, Maria G, Farmakis, Dimitrios, Gilard, Martine, Heymans, Stephane, Hoes, Arno W, Jaarsma, Tiny, Jankowska, Ewa A, Lainscak, Mitja, Lam, Carolyn S P, Lyon, Alexander R, McMurray, John J V, Mebazaa, Alexandre, Mindham, Richard, Muneretto, Claudio, Francesco Piepoli, Massimo, Price, Susanna, Rosano, Giuseppe M C, Ruschitzka, Frank, Kathrine Skibelund, Anne

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Practical recommendations for the management of diabetes in patients with COVID-19 von Bornstein, Stefan R, Rubino, Francesco, Khunti, Kamlesh, Mingrone, Geltrude, Hopkins, David, Birkenfeld, Andreas L, Boehm, Bernhard, Amiel, Stephanie, Holt, Richard IG, Skyler, Jay S, DeVries, J Hans, Renard, Eric, Eckel, Robert H, Zimmet, Paul, Alberti, Kurt George, Vidal, Josep, Geloneze, Bruno, Chan, Juliana C, Ji, Linong, Ludwig, Barbara

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Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk von Fischer, Annegret, Ellinghaus, David, Nutsua, Marcel, Hofmann, Sylvia, Montgomery, Courtney G, Iannuzzi, Michael C, Rybicki, Benjamin A, Petrek, Martin, Mrazek, Frantisek, Pabst, Stefan, Grohé, Christian, Grunewald, Johan, Ronninger, Marcus, Eklund, Anders, Padyukov, Leonid, Mihailovic-Vucinic, Violeta, Jovanovic, Dragana, Sterclova, Martina, Homolka, Jiri, Nöthen, Markus M, Herms, Stefan, Gieger, Christian, Strauch, Konstantin, Winkelmann, Juliane, Boehm, Bernhard O, Brand, Stephan, Büning, Carsten, Schürmann, Manfred, Ellinghaus, Eva, Baurecht, Hansjörg, Lieb, Wolfgang, Nebel, Almut, Müller-Quernheim, Joachim, Franke, Andre, Schreiber, Stefan

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Systematic RNA interference reveals that oncogenic KRAS -driven cancers require TBK1 von Kim, So Young, Sabatini, David M, Michel, Kathrin, Tamayo, Pablo, Weir, Barbara A, Le, Hanh, Mermel, Craig, Gupta, Piyush B, Meyerson, Matthew, Hahn, William C, Schinzel, Anna C, Hoersch, Sebastian, Lander, Eric S, Sandy, Peter, Mesirov, Jill P, Sheng, Qing, Boehm, Jesse S, Meylan, Etienne, Gilliland, D. Gary, Barbie, David A, Sos, Martin L, Fröhling, Stefan, Chan, Edmond M, Wittner, Ben S, Ramaswamy, Sridhar, Livingston, David M, Root, David E, Reiling, Jan H, Wadlow, Raymond C, Dunn, Ian F, Thomas, Roman K, Scholl, Claudia, Moody, Susan E, Silver, Serena J, Jacks, Tyler

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Worsening of chronic heart failure: definition, epidemiology, management and prevention. A clinical consensus statement by the Heart Failure Association of the European Society of... von Metra, Marco, Tomasoni, Daniela, Adamo, Marianna, Bayes‐Genis, Antoni, Filippatos, Gerasimos, Abdelhamid, Magdy, Adamopoulos, Stamatis, Anker, Stefan D., Antohi, Laura, Böhm, Michael, Braunschweig, Frieder, Gal, Tuvia Ben, Butler, Javed, Cleland, John G.F., Cohen‐Solal, Alain, Damman, Kevin, Gustafsson, Finn, Hill, Loreena, Jankowska, Ewa A., Lainscak, Mitja, Lund, Lars H., McDonagh, Theresa, Mebazaa, Alexandre, Moura, Brenda, Mullens, Wilfried, Piepoli, Massimo, Ponikowski, Piotr, Rakisheva, Amina, Ristic, Arsen, Savarese, Gianluigi, Seferovic, Petar, Sharma, Rajan, Tocchetti, Carlo Gabriele, Yilmaz, Mehmet Birhan, Vitale, Cristiana, Volterrani, Maurizio, Haehling, Stephan, Chioncel, Ovidiu, Coats, Andrew J.S., Rosano, Giuseppe

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Biodiversity at multiple trophic levels is needed for ecosystem multifunctionality von Soliveres, Santiago, van der Plas, Fons, Manning, Peter, Prati, Daniel, Gossner, Martin M., Renner, Swen C., Alt, Fabian, Arndt, Hartmut, Baumgartner, Vanessa, Binkenstein, Julia, Birkhofer, Klaus, Blaser, Stefan, Blüthgen, Nico, Boch, Steffen, Böhm, Stefan, Börschig, Carmen, Buscot, Francois, Diekötter, Tim, Heinze, Johannes, Hölzel, Norbert, Jung, Kirsten, Klaus, Valentin H., Kleinebecker, Till, Klemmer, Sandra, Krauss, Jochen, Lange, Markus, Morris, E. Kathryn, Müller, Jörg, Oelmann, Yvonne, Overmann, Jörg, Pašalić, Esther, Rillig, Matthias C., Schaefer, H. Martin, Schloter, Michael, Schmitt, Barbara, Schöning, Ingo, Schrumpf, Marion, Sikorski, Johannes, Socher, Stephanie A., Solly, Emily F., Sonnemann, Ilja, Sorkau, Elisabeth, Steckel, Juliane, Steffan-Dewenter, Ingolf, Stempfhuber, Barbara, Tschapka, Marco, Türke, Manfred, Venter, Paul C., Weiner, Christiane N., Weisser, Wolfgang W., Werner, Michael, Westphal, Catrin, Wilcke, Wolfgang, Wolters, Volkmar, Wubet, Tesfaye, Wurst, Susanne, Fischer, Markus, Allan, Eric

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Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality von Schunk, Stefan J, Kleber, Marcus E, März, Winfried, Pang, Shichao, Zewinger, Stephen, Triem, Sarah, Ege, Philipp, Reichert, Matthias C, Krawczyk, Marcin, Weber, Susanne N, Jaumann, Isabella, Schmit, David, Sarakpi, Tamim, Wagenpfeil, Stefan, Kramann, Rafael, Boerwinkle, Eric, Ballantyne, Christie M, Grove, Megan L, Tragante, Vinicius, Pilbrow, Anna P, Richards, A Mark, Cameron, Vicky A, Doughty, Robert N, Dubé, Marie-Pierre, Tardif, Jean-Claude, Feroz-Zada, Yassamin, Sun, Maxine, Liu, Chang, Ko, Yi-An, Quyyumi, Arshed A, Hartiala, Jaana A, Tang, W H Wilson, Hazen, Stanley L, Allayee, Hooman, McDonough, Caitrin W, Gong, Yan, Cooper-DeHoff, Rhonda M, Johnson, Julie A, Scholz, Markus, Teren, Andrej, Burkhardt, Ralph, Martinsson, Andreas, Smith, J Gustav, Wallentin, Lars, James, Stefan K, Eriksson, Niclas, White, Harvey, Held, Claes, Waterworth, Dawn, Trompet, Stella, Jukema, J Wouter, Ford, Ian, Stott, David J, Sattar, Naveed, Cresci, Sharon, Spertus, John A, Campbell, Hannah, Tierling, Sascha, Walter, Jörn, Ampofo, Emmanuel, Niemeyer, Barbara A, Lipp, Peter, Schunkert, Heribert, Böhm, Michael, Koenig, Wolfgang, Fliser, Danilo, Laufs, Ulrich, Speer, Thimoteus

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Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency von Freitag, Nancy, Tirado-Gonzalez, Irene, Barrientos, Gabriela, Powell, Katie L., Boehm-Sturm, Philipp, Koch, Stefan P., Hecher, Kurt, Staff, Anne C., Arck, Petra C., Diemert, Anke, Blois, Sandra M.

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A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery von Meybohm, Patrick, Bein, Berthold, Brosteanu, Oana, Cremer, Jochen, Gruenewald, Matthias, Stoppe, Christian, Coburn, Mark, Schaelte, Gereon, Böning, Andreas, Niemann, Bernd, Roesner, Jan, Kletzin, Frank, Strouhal, Ulrich, Reyher, Christian, Laufenberg-Feldmann, Rita, Ferner, Marion, Brandes, Ivo F, Bauer, Martin, Stehr, Sebastian N, Kortgen, Andreas, Wittmann, Maria, Baumgarten, Georg, Meyer-Treschan, Tanja, Kienbaum, Peter, Heringlake, Matthias, Schön, Julika, Sander, Michael, Treskatsch, Sascha, Smul, Thorsten, Wolwender, Ewa, Schilling, Thomas, Fuernau, Georg, Hasenclever, Dirk, Zacharowski, Kai

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Patient profiling in heart failure for tailoring medical therapy. A consensus document of the Heart Failure Association of the European Society of Cardiology von Rosano, Giuseppe M.C., Moura, Brenda, Metra, Marco, Böhm, Michael, Bauersachs, Johann, Ben Gal, Tuvia, Adamopoulos, Stamatis, Abdelhamid, Magdy, Bistola, Vasiliki, Čelutkienė, Jelena, Chioncel, Ovidiu, Farmakis, Dimitrios, Ferrari, Roberto, Filippatos, Gerasimos, Hill, Loreena, Jankowska, Ewa A., Jaarsma, Tiny, Jhund, Pardeep, Lainscak, Mitja, Lopatin, Yuri, Lund, Lars H., Milicic, Davor, Mullens, Wilfried, Pinto, Fausto, Ponikowski, Piotr, Savarese, Gianluigi, Thum, Thomas, Volterrani, Maurizio, Anker, Stefan D., Seferovic, Petar M., Coats, Andrew J.S.

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Low homoarginine concentration is a novel risk factor for heart disease von Pilz, Stefan, Meinitzer, Andreas, Tomaschitz, Andreas, Drechsler, Christiane, Ritz, Eberhard, Krane, Vera, Wanner, Christoph, Boehm, Bernhard O, März, Winfried

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Vaginal Ureaplasma parvum serovars and spontaneous preterm birth von Rittenschober-Böhm, Judith, Waldhoer, Thomas, Schulz, Stefan M., Pimpel, Birgit, Goeral, Katharina, Kasper, David C., Witt, Armin, Berger, Angelika

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Universal definition and classification of heart failure: a report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanes... von Bozkurt, Biykem, Coats, Andrew J.S., Tsutsui, Hiroyuki, Abdelhamid, Ca Magdy, Adamopoulos, Stamatis, Albert, Nancy, Anker, Stefan D., Atherton, John, Böhm, Michael, Butler, Javed, Drazner, Mark H., Michael Felker, G., Filippatos, Gerasimos, Fiuzat, Mona, Fonarow, Gregg C., Gomez‐Mesa, Juan‐Esteban, Heidenreich, Paul, Imamura, Teruhiko, Jankowska, Ewa A., Januzzi, James, Khazanie, Prateeti, Kinugawa, Koichiro, Lam, Carolyn S.P., Matsue, Yuya, Metra, Marco, Ohtani, Tomohito, Francesco Piepoli, Massimo, Ponikowski, Piotr, Rosano, Giuseppe M.C., Sakata, Yasushi, Seferović, Petar, Starling, Randall C., Teerlink, John R., Vardeny, Orly, Yamamoto, Kazuhiro, Yancy, Clyde, Zhang, Jian, Zieroth, Shelley

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Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling von Corsello, Steven M, Nagari, Rohith T, Spangler, Ryan D, Rossen, Jordan, Kocak, Mustafa, Bryan, Jordan G, Humeidi, Ranad, Peck, David, Wu, Xiaoyun, Tang, Andrew A, Wang, Vickie M, Bender, Samantha A, Lemire, Evan, Narayan, Rajiv, Montgomery, Philip, Ben-David, Uri, Garvie, Colin W, Chen, Yejia, Rees, Matthew G, Lyons, Nicholas J, McFarland, James M, Wong, Bang T, Wang, Li, Dumont, Nancy, O'Hearn, Patrick J, Stefan, Eric, Doench, John G, Harrington, Caitlin N, Greulich, Heidi, Meyerson, Matthew, Vazquez, Francisca, Subramanian, Aravind, Roth, Jennifer A, Bittker, Joshua A, Boehm, Jesse S, Mader, Christopher C, Tsherniak, Aviad, Golub, Todd R

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