Attenuation of miR-126 Activity Expands HSC In Vivo without Exhaustion von Lechman, Eric R., Gentner, Bernhard, van Galen, Peter, Giustacchini, Alice, Saini, Massimo, Boccalatte, Francesco E., Hiramatsu, Hidefumi, Restuccia, Umberto, Bachi, Angela, Voisin, Veronique, Bader, Gary D., Dick, John E., Naldini, Luigi

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Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy von Zonari, Erika, Desantis, Giacomo, Petrillo, Carolina, Boccalatte, Francesco E., Lidonnici, Maria Rosa, Kajaste-Rudnitski, Anna, Aiuti, Alessandro, Ferrari, Giuliana, Naldini, Luigi, Gentner, Bernhard

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Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages von Boytard, Ludovic, Hadi, Tarik, Silvestro, Michele, Qu, Hengdong, Kumpfbeck, Andrew, Sleiman, Rayan, Fils, Kissinger Hyppolite, Alebrahim, Dornazsadat, Boccalatte, Francesco, Kugler, Matthias, Corsica, Annanina, Gelb, Bruce E., Jacobowitz, Glenn, Miller, George, Bellini, Chiara, Oakes, Jessica, Silvestre, Jean-Sébastien, Zangi, Lior, Ramkhelawon, Bhama

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The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells von King, Bryan, Boccalatte, Francesco, Moran-Crusio, Kelly, Wolf, Elmar, Wang, Jingjing, Kayembe, Clarisse, Lazaris, Charalampos, Yu, Xiaofeng, Aranda-Orgilles, Beatriz, Lasorella, Anna, Aifantis, Iannis

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Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL von Rodriguez, Sonia, Abundis, Christina, Boccalatte, Francesco, Mehrotra, Purvi, Chiang, Mark Y., Yui, Mary A., Wang, Lin, Zhang, Huajia, Zollman, Amy, Bonfim-Silva, Ricardo, Kloetgen, Andreas, Palmer, Joycelynne, Sandusky, George, Wunderlich, Mark, Kaplan, Mark H., Mulloy, James C., Marcucci, Guido, Aifantis, Iannis, Cardoso, Angelo A., Carlesso, Nadia

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Functional changes in prefrontal cortex following frequency-specific training von Bach-Morrow, Lana, Boccalatte, Francesco, DeRosa, Antonio, Devos, David, Garcia-Sanchez, Carmen, Inglese, Matilde, Droby, Amgad

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Chromatin accessibility and cell cycle progression are controlled by the HDAC-associated Sin3B protein in murine hematopoietic stem cells von Calderon, Alexander, Mestvirishvili, Tamara, Boccalatte, Francesco, Ruggles, Kelly V, David, Gregory

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Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes von Piva, Roberto, Pellegrino, Elisa, Mattioli, Michela, Agnelli, Luca, Lombardi, Luigia, Boccalatte, Francesco, Costa, Giulia, Ruggeri, Bruce A, Cheng, Mangeng, Chiarle, Roberto, Palestro, Giorgio, Neri, Antonino, Inghirami, Giorgio

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The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and t... von Boccalatte, Francesco E., Voena, Claudia, Riganti, Chiara, Bosia, Amalia, D'Amico, Lucia, Riera, Ludovica, Cheng, Mangeng, Ruggeri, Bruce, Jensen, Ole N., Goss, Valerie L., Lee, Kimberly, Nardone, Julie, Rush, John, Polakiewicz, Roberto D., Comb, Michael J., Chiarle, Roberto, Inghirami, Giorgio

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Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening von Tan, Jimin, Shenker-Tauris, Nina, Rodriguez-Hernaez, Javier, Wang, Eric, Sakellaropoulos, Theodore, Boccalatte, Francesco, Thandapani, Palaniraja, Skok, Jane, Aifantis, Iannis, Fenyö, David, Xia, Bo, Tsirigos, Aristotelis

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CRL4AMBRA1 is a master regulator of D-type cyclins von Simoneschi, Daniele, Rona, Gergely, Zhou, Nan, Jeong, Yeon-Tae, Jiang, Shaowen, Milletti, Giacomo, Arbini, Arnaldo A., O’Sullivan, Alfie, Wang, Andrew A., Nithikasem, Sorasicha, Keegan, Sarah, Siu, Yik, Cianfanelli, Valentina, Maiani, Emiliano, Nazio, Francesca, Cecconi, Francesco, Boccalatte, Francesco, Fenyö, David, Jones, Drew R., Busino, Luca, Pagano, Michele

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Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia von Kloetgen, Andreas, Thandapani, Palaniraja, Ntziachristos, Panagiotis, Ghebrechristos, Yohana, Nomikou, Sofia, Lazaris, Charalampos, Chen, Xufeng, Hu, Hai, Bakogianni, Sofia, Wang, Jingjing, Fu, Yi, Boccalatte, Francesco, Zhong, Hua, Paietta, Elisabeth, Trimarchi, Thomas, Zhu, Yixing, Van Vlierberghe, Pieter, Inghirami, Giorgio G., Lionnet, Timothee, Aifantis, Iannis, Tsirigos, Aristotelis

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223Ra Induces Transient Functional Bone Marrow Toxicity von Parlani, Maria, Boccalatte, Francesco, Yeaton, Anna, Wang, Feng, Zhang, Jianhua, Aifantis, Iannis, Dondossola, Eleonora

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223 Ra Induces Transient Functional Bone Marrow Toxicity von Parlani, Maria, Boccalatte, Francesco, Yeaton, Anna, Wang, Feng, Zhang, Jianhua, Aifantis, Iannis, Dondossola, Eleonora

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3D chromatin hubs as regulatory units of identity and survival in human acute leukemia von Gambi, Giovanni, Boccalatte, Francesco, Rodriguez Hernaez, Javier, Lin, Ziyan, Nadorp, Bettina, Polyzos, Alexander, Tan, Jimin, Avrampou, Kleopatra, Inghirami, Giorgio, Kentsis, Alex, Apostolou, Effie, Aifantis, Iannis, Tsirigos, Aristotelis

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Assessment of tocilizumab in the treatment of cancer cachexia von Berti, Alvise, Boccalatte, Francesco, Sabbadini, Maria Grazia, Dagna, Lorenzo

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Endothelial cell–leukemia interactions remodel drug responses, uncovering T-ALL vulnerabilities von Cappelli, Luca Vincenzo, Fiore, Danilo, Phillip, Jude M., Yoffe, Liron, Di Giacomo, Filomena, Chiu, William, Hu, Yang, Kayembe, Clarisse, Ginsberg, Michael, Consolino, Lorena, Barcia Duran, Jose Gabriel, Zamponi, Nahuel, Melnick, Ari M., Boccalatte, Francesco, Tam, Wayne, Elemento, Olivier, Chiaretti, Sabina, Guarini, Anna, Foà, Robin, Cerchietti, Leandro, Rafii, Shahin, Inghirami, Giorgio

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Advances and Hurdles in CAR T Cell Immune Therapy for Solid Tumors von Boccalatte, Francesco, Mina, Roberto, Aroldi, Andrea, Leone, Sarah, Suryadevara, Carter M, Placantonakis, Dimitris G, Bruno, Benedetto

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miRNA-126 Orchestrates an Oncogenic Program in B Cell Precursor Acute Lymphoblastic Leukemia von Nucera, Silvia, Giustacchini, Alice, Boccalatte, Francesco, Calabria, Andrea, Fanciullo, Cristiana, Plati, Tiziana, Ranghetti, Anna, Garcia-Manteiga, Jose, Cittaro, Davide, Benedicenti, Fabrizio, Lechman, Eric R., Dick, John E., Ponzoni, Maurilio, Ciceri, Fabio, Montini, Eugenio, Gentner, Bernhard, Naldini, Luigi

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CRL4.sup.AMBRA1 is a master regulator of D-type cyclins von Simoneschi, Daniele, Rona, Gergely, Zhou, Nan, Jeong, Yeon-Tae, Jiang, Shaowen, Milletti, Giacomo, Arbini, Arnaldo A, O'Sullivan, Alfie, Wang, Andrew A, Nithikasem, Sorasicha, Keegan, Sarah, Siu, Yik, Cianfanelli, Valentina, Maiani, Emiliano, Nazio, Francesca, Cecconi, Francesco, Boccalatte, Francesco

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