Synthesis of 2,5-disubstituted-3-cyanoindoles von Bobko, Mark A., Evans, Karen A., Kaura, Arun C., Shuster, Leanna E., Su, Dai-Shi

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Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach von Smith, Roger A, Barbosa, James, Blum, Cheri L, Bobko, Mark A, Caringal, Yolanda V, Dally, Robert, Johnson, Jeffrey S, Katz, Michael E, Kennure, Nancy, Kingery-Wood, Jill, Lee, Wendy, Lowinger, Timothy B, Lyons, John, Marsh, Vivienne, Rogers, Daniel H, Swartz, Stephen, Walling, Tracy, Wild, Hanno

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Novel Synthesis of 5-Amino-3-bromo-1-(tert-butyl)-1H-pyrazole-4-carbonitrile: A Versatile Intermediate for the Preparation of 5-Amino-3-aryl-1-(tert-butyl)-1H-pyrazole-4-carboxamid... von Bobko, Mark A, Kaura, Arun C, Evans, Karen A, Su, Dai-Shi

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Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors von Medina, Jesús R, Becker, Christopher J, Blackledge, Charles W, Duquenne, Celine, Feng, Yanhong, Grant, Seth W, Heerding, Dirk, Li, William H, Miller, William H, Romeril, Stuart P, Scherzer, Daryl, Shu, Arthur, Bobko, Mark A, Chadderton, Antony R, Dumble, Melissa, Gardiner, Christine M, Gilbert, Seth, Liu, Qi, Rabindran, Sridhar K, Sudakin, Valery, Xiang, Hong, Brady, Pat G, Campobasso, Nino, Ward, Paris, Axten, Jeffrey M

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Rapid synthesis of diversely functionalized 3,4,7-trisubstituted indoles von Grant, Seth W., Gallagher, Timothy F., Bobko, Mark A., Duquenne, Celine, Axten, Jeffrey M.

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Acylprolinamides: A new class of peptide deformylase inhibitors with in vivo antibacterial activity von Axten, Jeffrey M., Medina, Jesús R., Blackledge, Charles W., Duquenne, Céline, Grant, Seth W., Bobko, Mark A., Peng, Tony, Miller, William H., Pinckney, Theresa, Gallagher, Timothy F., Kulkarni, Swarupa, Lewandowski, Thomas, Van Aller, Glenn S., Zonis, Rimma, Ward, Paris, Campobasso, Nino

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Expeditious Synthesis of a Potent Allosteric HIV‑1 Integrase Inhibitor GSK3839919A von Bobko, Mark A., Elward, Jennifer M., Naidu, B. Narasimhulu, Nieves-Quinones, Yexenia E., Reiher, Christopher A., Su, Qiaogong, Sun, Liang, Woodard, John, Xie, Shiping, Yang, Wuxing, Yin, Yunxing

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Discovery and SAR of novel [1,6]Naphthyridines as potent inhibitors of spleen tyrosine kinase (SYK) von Cywin, Charles L, Zhao, Bao-Ping, McNeil, Daniel W, Hrapchak, Matt, Prokopowicz, Anthony S, Goldberg, Daniel R, Morwick, Tina M, Gao, Amy, Jakes, Scott, Kashem, Mohammed, Magolda, Ronald L, Soll, Richard M, Player, Mark R, Bobko, Mark A, Rinker, James, DesJarlais, Renee L, Winters, Michael P

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Optimization of the 4-aryl group of 4-aryl-pyridine glucagon antagonists: development of an efficient, alternative synthesis von Smith, Roger A., Hertzog, Donald L., Osterhout, Martin H., Ladouceur, Gaetan H., Korpusik, Mary, Bobko, Mark A., Jones, J.Howard, Phelan, Kathleen, Romero, Romulo H., Hundertmark, Thomas, MacDougall, Margit L., Livingston, James N., Schoen, William R.

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Novel Synthesis of 5-Amino-3-bromo-1-( tert- butyl)-1 H -pyrazole-4-carbonitrile: A Versatile Intermediate for the Preparation of 5-Amino-3-aryl-1-( tert- butyl)-1 H -pyrazole-4-ca... von Bobko, Mark A., Kaura, Arun C., Evans, Karen A., Su, Dai-Shi

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Analogues of human parathyroid hormone (1-31)NH2; further evaluation of the effect of conformational constraint on biological activity von CONDON, Stephen M, DARNBROUGH, Shelley, BURNS, Christopher J, BOBKO, Mark A, MORIZE, Isabelle, UHL, Joanne, JARIWALA, Navinchandra U, BURKE, Kathleen, LABAUDINIERE, Richard F

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Structure, determination, pharmacological evaluation, and structure-activity studies of a new cyclic peptide substance P antagonist containing the new amino acid 3-prenyl-.beta.-hy... von Barrow, Colin J, Doleman, Muriel S, Bobko, Mark A, Cooper, Raymond

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ChemInform Abstract: Novel Synthesis of 5-Amino-3-bromo-1-(tert-butyl)-1H-pyrazole-4-carbonitrile: A Versatile Intermediate for the Preparation of 5-Amino-3-aryl-1-(tert-butyl)-1H-... von Bobko, Mark A., Kaura, Arun C., Evans, Karen A., Su, Dai-Shi

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ChemInform Abstract: Synthesis of 2,5-Disubstituted-3-cyanoindoles von Bobko, Mark A., Evans, Karen A., Kaura, Arun C., Shuster, Leanna E., Su, Dai-Shi

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ISOLATION AND STRUCTURE ELUCIDATION OF TWO NEW CALPAIN INHIBITORS FROM Streptomyces griseus von ALVAREZ, M. ESTELA, HOUCK, DAVID R., WHITE, CAROLE B., BROWNELL, JAMES E., BOBKO, MARK A., RODGER, CHARLES A., STAWICKI, MARY B., SUN, HAO H., GILLUM, AMANDA M., COOPER, RAYMOND

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Solid-phase synthesis of a library of piperazinediones and diazepinediones via kaiser oxime resin von Smith, Roger A., Bobko, Mark A., Lee, Wendy

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Synthesis, Characterization, and Conformational Analysis of the D/L-Tic7 Stereoisomers of Bradykinin Receptor Antagonist D-Arg0[Hyp3,Thi5,D-Tic7,Oic8]bradykinin von Sawutz, David G, Salvino, Joseph M, Seoane, Peter R, Douty, Brent D, Houck, Wayne T, Bobko, Mark A, Doleman, Muriel S, Dolle, Roland E, Wolfe, Henry R

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Analogues of human parathyroid hormone (1-31)NH(2): further evaluation of the effect of conformational constraint on biological activity von Condon, Stephen M, Darnbrough, Shelley, Burns, Christopher J, Bobko, Mark A, Morize, Isabelle, Uhl, Joanne, Jariwala, Navinchandra U, Burke, Kathleen, Labaudiniere, Richard F

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Analogues of Human Parathyroid Hormone (1–31)NH 2: Further Evaluation of the Effect of Conformational Constraint on Biological Activity von Condon, Stephen M, Darnbrough, Shelley, Burns, Christopher J, Bobko, Mark A, Morize, Isabelle, Uhl, Joanne, Jariwala, Navinchandra U, Burke, Kathleen, Labaudiniere, Richard F

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ChemInform Abstract: Rapid Synthesis of Diversely Functionalized 3,4,7-Trisubstituted Indoles von Grant, Seth W., Gallagher, Timothy F., Bobko, Mark A., Duquenne, Celine, Axten, Jeffrey M.

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