IgG Fusion Proteins for Brain Delivery of Biologics via Blood–Brain Barrier Receptor-Mediated Transport von Boado, Ruben J.

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Reengineering Biopharmaceuticals for Targeted Delivery Across the Blood–Brain Barrier von Pardridge, William M., Boado, Ruben J.

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Brain and Organ Uptake in the Rhesus Monkey in Vivo of Recombinant Iduronidase Compared to an Insulin Receptor Antibody–Iduronidase Fusion Protein von Boado, Ruben J, Pardridge, William M

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Neurocognitive and somatic stabilization in pediatric patients with severe Mucopolysaccharidosis Type I after 52 weeks of intravenous brain-penetrating insulin receptor antibody-id... von Giugliani, Roberto, Giugliani, Luciana, de Oliveira Poswar, Fabiano, Donis, Karina Carvalho, Corte, Amauri Dalla, Schmidt, Mathias, Boado, Ruben J, Nestrasil, Igor, Nguyen, Carol, Chen, Steven, Pardridge, William M

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Immunologic Privilege in the Central Nervous System and the Blood–Brain Barrier von Muldoon, Leslie L, Alvarez, Jorge I, Begley, David J, Boado, Ruben J, del Zoppo, Gregory J, Doolittle, Nancy D, Engelhardt, Britta, Hallenbeck, John M, Lonser, Russell R, Ohlfest, John R, Prat, Alexandre, Scarpa, Maurizio, Smeyne, Richard J, Drewes, Lester R, Neuwelt, Edward A

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Blood-brain barrier transport of non-viral gene and RNAi therapeutics von Boado, Ruben J

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Insulin receptor antibody-iduronate 2-sulfatase fusion protein: Pharmacokinetics, anti-drug antibody, and safety pharmacology in Rhesus monkeys von Boado, Ruben J., Ka-Wai Hui, Eric, Zhiqiang Lu, Jeff, Pardridge, William M.

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Engineering and expression of a chimeric transferrin receptor monoclonal antibody for blood-brain barrier delivery in the mouse von Boado, Ruben J, Zhang, Yun, Wang, Yuntao, Pardridge, William M

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Blood-Brain Barrier Molecular Trojan Horse Enables Imaging of Brain Uptake of Radioiodinated Recombinant Protein in the Rhesus Monkey von Boado, Ruben J, Hui, Eric K.-W, Lu, Jeff Zhiqiang, Sumbria, Rachita K, Pardridge, William M

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Comparison of Blood-Brain Barrier Transport of Glial-Derived Neurotrophic Factor (GDNF) and an IgG-GDNF Fusion Protein in the Rhesus Monkey von Boado, Ruben J., Pardridge, William M.

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Intravenous RNA Interference Gene Therapy Targeting the Human Epidermal Growth Factor Receptor Prolongs Survival in Intracranial Brain Cancer von YUN ZHANG, ZHANG, Yu-Feng, BRYANT, Joshua, CHARLES, Andrew, BOADO, Ruben J, PARDRIDGE, William M

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Pharmacokinetics and brain uptake in the rhesus monkey of a fusion protein of arylsulfatase a and a monoclonal antibody against the human insulin receptor von Boado, Ruben J., Lu, Jeff Zhiqiang, Hui, Eric K.-W., Sumbria, Rachita K., Pardridge, William M.

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Genetic engineering of a lysosomal enzyme fusion protein for targeted delivery across the human blood-brain barrier von Boado, Ruben J, Zhang, Yun, Zhang, Yufeng, Xia, Chun-fang, Wang, Yuntao, Pardridge, William M

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GDNF fusion protein for targeted-drug delivery across the human blood-brain barrier von Boado, Ruben J, Zhang, Yun, Zhang, Yufeng, Wang, Yuntao, Pardridge, William M

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Pharmacokinetics and Brain Uptake of a Genetically Engineered Bifunctional Fusion Antibody Targeting the Mouse Transferrin Receptor von Boado, Ruben J, Zhou, Qing-Hui, Lu, Jeff Zhiqiang, Hui, Eric Ka-Wai, Pardridge, William M

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Genetic engineering, expression, and activity of a fusion protein of a human neurotrophin and a molecular Trojan horse for delivery across the human blood-brain barrier von Boado, Ruben J., Zhang, Yufeng, Zhang, Yun, Pardridge, William M.

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Brain-Specific Expression of an Exogenous Gene after i.v. Administration von Shi, Ningya, Zhang, Yun, Zhu, Chunni, Boado, Ruben J., Pardridge, William M.

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Pharmacokinetics and Brain Uptake of an IgG-TNF Decoy Receptor Fusion Protein Following Intravenous, Intraperitoneal, and Subcutaneous Administration in Mice von Sumbria, Rachita K, Zhou, Qing-Hui, Hui, Eric Ka-Wai, Lu, Jeff Zhiqiang, Boado, Ruben J, Pardridge, William M

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Brain-penetrating IgG-iduronate 2-sulfatase fusion protein for the mouse von Zhou, Qing-Hui, Boado, Ruben J, Lu, Jeff Zhiqiang, Hui, Eric Ka-Wai, Pardridge, William M

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Intravenous nonviral gene therapy causes normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism von YUN ZHANG, CALON, Frederic, CHUNNI ZHU, BOADO, Ruben J, PARDRIDGE, William M

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