Discovery of CP-690,550: A Potent and Selective Janus Kinase (JAK) Inhibitor for the Treatment of Autoimmune Diseases and Organ Transplant Rejection von Flanagan, Mark E, Blumenkopf, Todd A, Brissette, William H, Brown, Matthew F, Casavant, Jeffrey M, Shang-Poa, Chang, Doty, Jonathan L, Elliott, Eileen A, Fisher, Michael B, Hines, Michael, Kent, Craig, Kudlacz, Elizabeth M, Lillie, Brett M, Magnuson, Kelly S, McCurdy, Sandra P, Munchhof, Michael J, Perry, Bret D, Sawyer, Perry S, Strelevitz, Timothy J, Subramanyam, Chakrapani, Sun, Jianmin, Whipple, David A, Changelian, Paul S

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Preparation of eight-membered cyclic ethers by Lewis acid promoted acetal-alkene cyclizations von Blumenkopf, Todd A, Bratz, Matthias, Castaneda, Armando, Look, Gary C, Overman, Larry E, Rodriguez, Domingo, Thompson, Andrew S

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Ryanodine Action at Calcium Release Channels. 1. Importance of Hydroxyl Substituents von Jefferies, Phillip R, Blumenkopf, Todd A, Gengo, Peter J, Cole, Loretta C, Casida, John E

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Acetal-initiated cyclizations of vinylsilanes. A general synthesis of allylically unsaturated oxacyclics von Overman, Larry E, Castaneda, Armando, Blumenkopf, Todd A

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Stereochemistry of the Sakurai reaction. Additions to cyclohexenones and cycloheptenones von Blumenkopf, Todd A, Heathcock, Clayton H

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Total synthesis of (.+-.)-fawcettimine (Burnell's base A) von Heathcock, Clayton H, Smith, Karl M, Blumenkopf, Todd A

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Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor von Changelian, Paul S., Flanagan, Mark E., Ball, Douglas J., Kent, Craig R., Magnuson, Kelly S., Martin, William H., Rizzuti, Bonnie J., Sawyer, Perry S., Perry, Bret D., Brissette, William H., McCurdy, Sandra P., Kudlacz, Elizabeth M., Conklyn, Maryrose J., Elliott, Eileen A., Koslov, Erika R., Fisher, Michael B., Strelevitz, Timothy J., Yoon, Kwansik, Whipple, David A., Sun, Jianmin, Munchhof, Michael J., Doty, John L., Casavant, Jeffrey M., Blumenkopf, Todd A., Hines, Michael, Brown, Matthew F., Lillie, Brett M., Subramanyam, Chakrapani, Shang-Poa, Chang, Milici, Anthony J., Beckius, Gretchen E., Moyer, James D., Su, Chunyan, Woodworth, Thasia C., Gaweco, Anderson S., Beals, Chan R., Littman, Bruce H., Fisher, Douglas A., Smith, James F., Zagouras, Panayiotis, Magna, Holly A., Saltarelli, Mary J., Johnson, Kimberly S., Nelms, Linda F., Shelley G. Des Etages, Hayes, Lisa S., Kawabata, Thomas T., Finco-Kent, Deborah, Baker, Deanna L., Larson, Michael, Si, Ming-Sing, Paniagua, Ricardo, Higgins, John, Holm, Bari, Reitz, Bruce, Zhou, Yong-Jie, Morris, Randall E., O'Shea, John J., Borie, Dominic C.

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Efficient preparations of 8- and 9-membered cyclic ethers von Overman, Larry E, Blumenkopf, Todd A, Castaneda, Armando, Thompson, Andrew S

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Total synthesis of (.+-.)-fawcettimine von Heathcock, Clayton H, Blumenkopf, Todd A, Smith, Karl M

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Formation of .DELTA.4-oxocenes from Lewis acid promoted cyclizations of 5-hexenyl acetals. Evidence for a concerted ene cyclization mechanism von Blumenkopf, Todd A, Look, Gary C, Overman, Larry E

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Acyclic stereoselection. 22. Diastereofacial selectivity in the Lewis acid mediated reactions of allylsilanes with chiral aldehydes and enones von Heathcock, Clayton H, Kiyooka, Syunichi, Blumenkopf, Todd A

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Abstract A177: Phase 1, dose-escalation, safety, pharmacokinetic and pharmacodynamic study of single agent PF-03758309, an oral PAK inhibitor, in patients with advanced solid tumor... von Rosen, Lee S., Blumenkopf, Todd A., Breazna, Aurora, Darang, Sheree, Gallo, Jorge D., Goldman, Jonathan, Wang, Diane, Mileshkin, Linda, Eckhardt, S. Gail

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2-Acetylpyridine thiocarbonohydrazones. Potent inactivators of herpes simplex virus ribonucleotide reductase von Blumenkopf, Todd A, Harrington, Joan A, Koble, Cecilia S, Bankston, Donald D, Morrison, Robert W, Bigham, Eric C, Styles, Virgil L, Spector, Thomas

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Toward Antibody-directed Enzyme Prodrug Therapy with the T268G Mutant of Human Carboxypeptidase A1 and Novel in VivoStable Prodrugs of Methotrexate von Smith, Gary K., Banks, Sheila, Blumenkopf, Todd A., Cory, Michael, Humphreys, Joan, Laethem, Ronald M., Miller, John, Moxham, Cary P., Mullin, Robert, Ray, Paul H., Walton, Leslie M., Wolfe, Lawrence A.

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Vinylsilane- and alkynylsilane-terminated cyclization reactions von Blumenkopf, Todd A, Overman, Larry E

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Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate von Smith, G K, Banks, S, Blumenkopf, T A, Cory, M, Humphreys, J, Laethem, R M, Miller, J, Moxham, C P, Mullin, R, Ray, P H, Walton, L M, Wolfe, 3rd, L A

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Mild methods for the [formula omitted] generation of trimethylsilyl iodide von Jung, Michael E., Blumenkopf, Todd A.

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Mobility handicapped individuals in the college chemistry curriculum: Students, teachers, and researchers von Blumenkopf, Todd A, Swanson, Anne Barrett, Larsen, Robert P

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Expression and Characterization of Human Pancreatic Preprocarboxypeptidase A1 and Preprocarboxypeptidase A2 von Laethem, Ronald M., Blumenkopf, Todd A., Cory, Michael, Elwell, Lynn, Moxham, Cary P., Ray, Paul H., Walton, Leslie M., Smith, Gary K.

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Pyrrolo[2,3-D]pyrimidine compounds von BLUMENKOPF TODD A

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