Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients von Bloom, A Joseph, Mao, Xianrong, Strickland, Amy, Sasaki, Yo, Milbrandt, Jeffrey, DiAntonio, Aaron

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Macrophage depletion blocks congenital SARM1-dependent neuropathy von Dingwall, Caitlin B, Strickland, Amy, Yum, Sabrina W, Yim, Aldrin Ky, Zhu, Jian, Wang, Peter L, Yamada, Yurie, Schmidt, Robert E, Sasaki, Yo, Bloom, A Joseph, DiAntonio, Aaron, Milbrandt, Jeffrey

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Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss von Wu, Tong, Zhu, Jian, Strickland, Amy, Ko, Kwang Woo, Sasaki, Yo, Dingwall, Caitlin B., Yamada, Yurie, Figley, Matthew D., Mao, Xianrong, Neiner, Alicia, Bloom, A. Joseph, DiAntonio, Aaron, Milbrandt, Jeffrey

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The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons von Bloom, A Joseph, Miller, Bradley R, Sanes, Joshua R, DiAntonio, Aaron

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CYP2B6 non-coding variation associated with smoking cessation is also associated with differences in allelic expression, splicing, and nicotine metabolism independent of common ami... von Bloom, A Joseph, Martinez, Maribel, Chen, Li-Shiun, Bierut, Laura J, Murphy, Sharon E, Goate, Alison

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Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy von Krus, Kelsey L, Strickland, Amy, Yamada, Yurie, Devault, Laura, Schmidt, Robert E, Bloom, A Joseph, Milbrandt, Jeffrey, DiAntonio, Aaron

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Two cardinal features of ALS, reduced STMN2 and pathogenic TDP-43, synergize to accelerate motor decline in mice von Krus, Kelsey L., Benitez, Ana Morales, Strickland, Amy, Milbrandt, Jeffrey, Bloom, A. Joseph, DiAntonio, Aaron

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Pharmacotherapy effects on smoking cessation vary with nicotine metabolism gene (CYP2A6) von Chen, Li-Shiun, Bloom, A. Joseph, Baker, Timothy B., Smith, Stevens S., Piper, Megan E., Martinez, Maribel, Saccone, Nancy, Hatsukami, Dorothy, Goate, Alison, Bierut, Laura

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Strain‐specific altered nicotine metabolism in 3,3′‐diindolylmethane (DIM) exposed mice von Bloom, A. Joseph, Upadhyaya, Pramod, Kharasch, Evan D.

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Variants in two adjacent genes, EGLN2 and CYP2A6, influence smoking behavior related to disease risk via different mechanisms von Bloom, A Joseph, Baker, Timothy B, Chen, Li-Shiun, Breslau, Naomi, Hatsukami, Dorothy, Bierut, Laura J, Goate, Alison

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Beyond cigarettes per day. A genome-wide association study of the biomarker carbon monoxide von Bloom, A Joseph, Hartz, Sarah M, Baker, Timothy B, Chen, Li-Shiun, Piper, Megan E, Fox, Louis, Martinez, Maribel, Hatsukami, Dorothy, Johnson, Eric O, Laurie, Cathy C, Saccone, Nancy L, Goate, Alison, Bierut, Laura J

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Effects upon in-vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumption von Bloom, A Joseph, Murphy, Sharon E, Martinez, Maribel, von Weymarn, Linda B, Bierut, Laura J, Goate, Alison

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A compensatory effect upon splicing results in normal function of the CYP2A614 allele von Bloom, A Joseph, Harari, Oscar, Martinez, Maribel, Zhang, Xiaochun, McDonald, Sandra A, Murphy, Sharon E, Goate, Alison

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Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6 von BLOOM, A. Joseph, HARARI, Oscar, MARTINEZ, Maribel, MADDEN, Pamela A. F, MARTIN, Nicholas G, MONTGOMERY, Grant W, RICE, John P, MURPHY, Sharon E, BIERUT, Laura J, GOATE, Alison

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The contribution of common UGT2B10 and CYP2A6 alleles to variation in nicotine glucuronidation among European Americans von Bloom, A Joseph, von Weymarn, Linda B, Martinez, Maribel, Bierut, Laura J, Goate, Alison, Murphy, Sharon E

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Phr1 regulates retinogeniculate targeting independent of activity and ephrin-A signalling von Culican, Susan M., Bloom, A. Joseph, Weiner, Joshua A., DiAntonio, Aaron

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Phr1 is required for proper retinocollicular targeting of nasal–dorsal retinal ganglion cells von VO, BRADLY Q., BLOOM, A. JOSEPH, CULICAN, SUSAN M.

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Macrophage depletion blocks congenital SARMI-dependent neuropathy von Dingwall, Caitlin B, Strickland, Amy, Yum, Sabrina W, Yim, Aldrin K.Y, Zhu, Jian, Wang, Peter L, Yamada, Yurie, Schmidt, Robert E, Sasaki, Yo, Bloom, A. Joseph, DiAntonio, Aaron, Milbrandt, Jeffrey

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The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European–Americans von Bloom, Joseph, Hinrichs, Anthony L, Wang, Jen C, von Weymarn, Linda B, Kharasch, Evan D, Bierut, Laura J, Goate, Alison, Murphy, Sharon E

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Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain von Teitelbaum, A M, Murphy, S E, Akk, G, Baker, T B, Germann, A, von Weymarn, L B, Bierut, L J, Goate, A, Kharasch, E D, Bloom, A J

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