Systems toxicogenomics of prenatal low-dose BPA exposure on liver metabolic pathways, gut microbiota, and metabolic health in mice von Diamante, Graciel, Cely, Ingrid, Zamora, Zacary, Ding, Jessica, Blencowe, Montgomery, Lang, Jennifer, Bline, Abigail, Singh, Maya, Lusis, Aldons J., Yang, Xia

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IAPP-induced beta cell stress recapitulates the islet transcriptome in type 2 diabetes von Blencowe, Montgomery, Furterer, Allison, Wang, Qing, Gao, Fuying, Rosenberger, Madeline, Pei, Lina, Nomoto, Hiroshi, Mawla, Alex M., Huising, Mark O., Coppola, Giovanni, Yang, Xia, Butler, Peter C., Gurlo, Tatyana

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Network Modeling Approaches and Applications to Unravelling Non-Alcoholic Fatty Liver Disease von Blencowe, Montgomery, Karunanayake, Tilan, Wier, Julian, Hsu, Neil, Yang, Xia

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Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation von Adlam, David, Berrandou, Takiy-Eddine, Georges, Adrien, Nelson, Christopher P., Giannoulatou, Eleni, Henry, Joséphine, Ma, Lijiang, Blencowe, Montgomery, Turley, Tamiel N., Yang, Min-Lee, Chopade, Sandesh, Finan, Chris, Braund, Peter S., Sadeg-Sayoud, Ines, Iismaa, Siiri E., Kosel, Matthew L., Zhou, Xiang, Hamby, Stephen E., Cheng, Jenny, Liu, Lu, Tarr, Ingrid, Muller, David W. M., d’Escamard, Valentina, King, Annette, Brunham, Liam R., Baranowska-Clarke, Ania A., Debette, Stéphanie, Amouyel, Philippe, Olin, Jeffrey W., Patil, Snehal, Hesselson, Stephanie E., Junday, Keerat, Kanoni, Stavroula, Aragam, Krishna G., Butterworth, Adam S., Tweet, Marysia S., Gulati, Rajiv, Combaret, Nicolas, Kadian-Dodov, Daniella, Kalman, Jonathan M., Fatkin, Diane, Hingorani, Aroon D., Saw, Jacqueline, Webb, Tom R., Hayes, Sharonne N., Yang, Xia, Ganesh, Santhi K., Olson, Timothy M., Kovacic, Jason C., Graham, Robert M., Samani, Nilesh J., Bouatia-Naji, Nabila

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Shared and distinct pathways and networks genetically linked to coronary artery disease between human and mouse von Kurt, Zeyneb, Cheng, Jenny, Barrere-Cain, Rio, McQuillen, Caden N, Saleem, Zara, Hsu, Neil, Jiang, Nuoya, Pan, Calvin, Franzén, Oscar, Koplev, Simon, Wang, Susanna, Björkegren, Johan, Lusis, Aldons J, Blencowe, Montgomery, Yang, Xia

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Ketogenic diet therapy for pediatric epilepsy is associated with alterations in the human gut microbiome that confer seizure resistance in mice von Lum, Gregory R., Ha, Sung Min, Olson, Christine A., Blencowe, Montgomery, Paramo, Jorge, Reyes, Beck, Matsumoto, Joyce H., Yang, Xia, Hsiao, Elaine Y.

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Multi‐Tissue Multi‐Omics Nutrigenomics Indicates Context‐Specific Effects of Docosahexaenoic Acid on Rat Brain von Zhang, Guanglin, Meng, Qingying, Blencowe, Montgomery, Agrawal, Rahul, Gomez‐Pinilla, Fernando, Yang, Xia

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Gene networks and pathways for plasma lipid traits via multitissue multiomics systems analysis von Blencowe, Montgomery, Ahn, In Sook, Saleem, Zara, Luk, Helen, Cely, Ingrid, Mäkinen, Ville-Petteri, Zhao, Yuqi, Yang, Xia

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Translating GWAS Findings to Novel Therapeutic Targets for Coronary Artery Disease von Shu, Le, Blencowe, Montgomery, Yang, Xia

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PharmOmics: A species- and tissue-specific drug signature database and gene-network-based drug repositioning tool von Chen, Yen-Wei, Diamante, Graciel, Ding, Jessica, Nghiem, Thien Xuan, Yang, Jessica, Ha, Sung-Min, Cohn, Peter, Arneson, Douglas, Blencowe, Montgomery, Garcia, Jennifer, Zaghari, Nima, Patel, Paul, Yang, Xia

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Maternal High-Protein and Low-Protein Diets Perturb Hypothalamus and Liver Transcriptome and Metabolic Homeostasis in Adult Mouse Offspring von Martin, Lisa J, Meng, Qingying, Blencowe, Montgomery, Lagarrigue, Sandrine, Xiao, Sheila, Pan, Calvin, Wier, Julian, Temple, William C, Devaskar, Sherin U, Lusis, Aldons J, Yang, Xia

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Integrative Genomics Analysis Unravels Tissue-Specific Pathways, Networks, and Key Regulators of Blood Pressure Regulation von Zhao, Yuqi, Blencowe, Montgomery, Shi, Xingyi, Shu, Le, Levian, Candace, Ahn, In Sook, Kim, Stuart K, Huan, Tianxiao, Levy, Daniel, Yang, Xia

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Found in translation-core network preservation across liver diseases and species von Blencowe, Montgomery, Yang, Xia

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Abstract 12437: Network-Based Identification of Tissue-Specific Regulators and Drug Repurposing Candidates for Coronary Artery Disease von Cheng, Jenny, Blencowe, Montgomery, Lusis, Aldons J, Yang, Xia

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1698-P: Integrative Genomics Analysis Reveals Tissue-Specific Pathways and Gene Networks for Type 1 Diabetes von BLENCOWE, MONTGOMERY, SALEEM, ZARA, YANG, XIA

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Mergeomics 2.0: a web server for multi-omics data integration to elucidate disease networks and predict therapeutics von Ding, Jessica, Blencowe, Montgomery, Nghiem, Thien, Ha, Sung-min, Chen, Yen-Wei, Li, Gaoyan, Yang, Xia

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2102-LB: Dysregulation of Cholesterol Homeostasis Is an Early Signal of Beta-Cell Proteotoxicity Characteristic of Type 2 Diabetes von Gurlo, Tatyana, Liu, Ruoshui, Yang, Xia, Blencowe, Montgomery, Butler, Peter C

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Relative contributions of sex hormones, sex chromosomes, and gonads to sex differences in tissue gene regulation von Blencowe, Montgomery, Chen, Xuqi, Zhao, Yutian, Itoh, Yuichiro, McQuillen, Caden N, Han, Yanjie, Shou, Benjamin L, McClusky, Rebecca, Reue, Karen, Arnold, Arthur P, Yang, Xia

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Dysregulation of cholesterol homeostasis is an early signal of β-cell proteotoxicity characteristic of type 2 diabetes von Gurlo, Tatyana, Liu, Ruoshui, Wang, Zhongying, Hoang, Jonathan, Ryazantsev, Sergey, Daval, Marie, Butler, Alexandra E, Yang, Xia, Blencowe, Montgomery, Butler, Peter C

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Differential metabolic and multi-tissue transcriptomic responses to fructose consumption among genetically diverse mice von Zhang, Guanglin, Byun, Hyae Ran, Ying, Zhe, Blencowe, Montgomery, Zhao, Yuqi, Hong, Jason, Shu, Le, Chella Krishnan, Karthick, Gomez-Pinilla, Fernando, Yang, Xia

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