Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia von Baginska, Joanna, Viry, Elodie, Berchem, Guy, Poli, Aurélie, Noman, Muhammad Zaeem, van Moer, Kris, Medves, Sandrine, Zimmer, Jacques, Oudin, Anaïs, Niclou, Simone P., Bleackley, R. Chris, Goping, Ing Swie, Chouaib, Salem, Janji, Bassam

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The unmet need in the elderly: How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines von McElhaney, Janet E, Zhou, Xin, Talbot, H. Keipp, Soethout, Ernst, Bleackley, R. Chris, Granville, David J, Pawelec, Graham

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Granzyme B: a natural born killer von Lord, Sarah J., Rajotte, Ray V., Korbutt, Gregory S., Bleackley, R. Chris

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Cloning CTL-Specific Genes (And Now for Something Completely Differential) von Bleackley, R Chris

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The Human Host Defense Peptide LL-37 Induces Apoptosis in a Calpain- and Apoptosis-Inducing Factor–Dependent Manner Involving Bax Activity von Mader, Jamie S, Mookherjee, Neeloffer, Hancock, Robert E W, Bleackley, R Chris

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Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3 von Marcet-Palacios, Marcelo, Duggan, Brenda Lee, Shostak, Irene, Barry, Michele, Geskes, Tracy, Wilkins, John A, Yanagiya, Akiko, Sonenberg, Nahum, Bleackley, R Chris

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Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells von Walch, Michael, Keefe, Dennis, Kirchhausen, Tomas, Thiery, Jerome, Goping, Ing Swie, Martinvalet, Denis, Boulant, Steeve, Lieberman, Judy, Bleackley, R Chris, Boucrot, Emmanuel

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Seasonal H1N1 Influenza Virus Infection Induces Cross-Protective Pandemic H1N1 Virus Immunity through a CD8-Independent, B Cell-Dependent Mechanism von YUAN FANG, BANNER, David, KELVIN, David J, KELVIN, Alyson A, HUANG, Stephen S. H, PAIGE, Christopher J, CORFE, Steven A, KANE, Kevin P, BLEACKLEY, R. Chris, ROWE, Thomas, LEON, Alberto J

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Granzyme B-Induced Apoptosis Requires Both Direct Caspase Activation and Relief of Caspase Inhibition von Goping, Ing Swie, Barry, Michele, Liston, Peter, Sawchuk, Tracy, Constantinescu, Gabriela, Michalak, Karolina M., Shostak, Irene, Roberts, Darren L., Hunter, Allison M., Korneluk, Robert, Bleackley, R. Chris

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Cytotoxic T lymphocytes: all roads lead to death von Barry, Michele, Bleackley, R. Chris

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Changes in Endoplasmic Reticulum Luminal Environment Affect Cell Sensitivity to Apoptosis von Nakamura, Kimitoshi, Bossy-Wetzel, Ella, Burns, Kimberly, Fadel, Marc P., Lozyk, Mira, Goping, Ing Swie, Opas, Michal, Bleackley, R. Chris, Green, Douglas R., Michalak, Marek

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CD4+CD25+CD127dimFoxp3+ T cells are cytotoxic for human neurons von Haile, Yohannes, Pasychniyk, Dion, Turner, Diane, Bleackley, R. Chris, Giuliani, Fabrizio

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Identification of a Novel Human Granzyme B Inhibitor Secreted by Cultured Sertoli Cells von Sipione, Simonetta, Simmen, Katia C, Lord, Sarah J, Motyka, Bruce, Ewen, Catherine, Shostak, Irene, Rayat, Gina R, Dufour, Jannette M, Korbutt, Greg S, Rajotte, Ray V, Bleackley, R. Chris

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Protection of Porcine Islet Xenografts in Mice Using Sertoli Cells and Monoclonal Antibodies von RAMJI, Qahir A, BAYRACK, Kevin, AREFANIAN, Hossein, MARCET-PALACIOS, Marcelo, BLEACKLEY, R. Chris, RAJOTTE, Ray V, RAYAT, Gina R

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Granzyme B-inhibitor serpina3n induces neuroprotection in vitro and in vivo von Haile, Yohannes, Carmine-Simmen, Katia, Olechowski, Camille, Kerr, Bradley, Bleackley, R Chris, Giuliani, Fabrizio

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Expression of CTL Associated Transcripts Precedes the Development of Tubulitis in T‐Cell Mediated Kidney Graft Rejection von Einecke, Gunilla, Melk, Anette, Ramassar, Vido, Zhu, Lin‐Fu, Bleackley, R. Chris, Famulski, Konrad S., Halloran, Philip F.

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T Cell Responses Are Better Correlates of Vaccine Protection in the Elderly von McElhaney, Janet E, Xie, Dongxu, Hager, W. David, Barry, Mary Beth, Wang, Yazhen, Kleppinger, Alison, Ewen, Catherine, Kane, Kevin P, Bleackley, R. Chris

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The myxoma poxvirus protein, M11L, prevents apoptosis by direct interaction with the mitochondrial permeability transition pore von Everett, Helen, Barry, Michele, Sun, Xuejun, Lee, Siow Fong, Frantz, Christine, Berthiaume, Luc G, McFadden, Grant, Bleackley, R Chris

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Blockade of Granzyme B Remarkably Improves Mucocutaneous Diseases with Keratinocyte Death in Interface Dermatitis von Saito, Akimasa, Okiyama, Naoko, Kubota, Noriko, Nakamura, Yoshiyuki, Fujisawa, Yasuhiro, Watanabe, Rei, Ishitsuka, Yosuke, Bleackley, R. Chris, Fujimoto, Manabu

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Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension von Sutendra, Gopinath, Dromparis, Peter, Bonnet, Sébastien, Haromy, Alois, McMurtry, Michael S., Bleackley, R. Chris, Michelakis, Evangelos D.

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