ABHD6 Blockade Exerts Antiepileptic Activity in PTZ-Induced Seizures and in Spontaneous Seizures in R6/2 Mice von Naydenov, Alipi V., Horne, Eric A., Cheah, Christine S., Swinney, Katie, Hsu, Ku-Lung, Cao, Jessica K., Marrs, William R., Blankman, Jacqueline L., Tu, Sarah, Cherry, Allison E., Fung, Susan, Wen, Andy, Li, Weiwei, Saporito, Michael S., Selley, Dana E., Cravatt, Benjamin F., Oakley, John C., Stella, Nephi

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Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders von Cisar, Justin S, Weber, Olivia D, Clapper, Jason R, Blankman, Jacqueline L, Henry, Cassandra L, Simon, Gabriel M, Alexander, Jessica P, Jones, Todd K, Ezekowitz, R. Alan B, O’Neill, Gary P, Grice, Cheryl A

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ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC von Blankman, Jacqueline L., Long, Jonathan Z., Trauger, Sunia A., Siuzdak, Gary, Cravatt, Benjamin F.

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In situ identification of cellular drug targets in mammalian tissue von Pang, Zhengyuan, Schafroth, Michael A., Ogasawara, Daisuke, Wang, Yu, Nudell, Victoria, Lal, Neeraj K., Yang, Dong, Wang, Kristina, Herbst, Dylan M., Ha, Jacquelyn, Guijas, Carlos, Blankman, Jacqueline L., Cravatt, Benjamin F., Ye, Li

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The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors von Marrs, William R, Blankman, Jacqueline L, Horne, Eric A, Thomazeau, Aurore, Lin, Yi Hsing, Coy, Jonathan, Bodor, Agnes L, Muccioli, Giulio G, Hu, Sherry Shu-Jung, Woodruff, Grace, Fung, Susan, Lafourcade, Mathieu, Alexander, Jessica P, Long, Jonathan Z, Li, Weiwei, Xu, Cong, Möller, Thomas, Mackie, Ken, Manzoni, Olivier J, Cravatt, Benjamin F, Stella, Nephi

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Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice von Pan, Bin, Wang, Wei, Zhong, Peng, Blankman, Jacqueline L, Cravatt, Benjamin F, Liu, Qing-song

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Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system von Kinsey, Steven G, Schlosburg, Joel E, Thomas, Elizabeth A, Cravatt, Benjamin F, Nomura, Daniel K, Selley, Dana E, Long, Jonathan Z, Sim-Selley, Laura J, Booker, Lamont, Liu, Qing-song, Blankman, Jacqueline L, Ramesh, Divya, Lichtman, Aron H, Nguyen, Peter T, Burston, James J, Pan, Bin

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Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening von Bachovchin, Daniel A., Ji, Tianyang, Li, Weiwei, Simon, Gabriel M., Blankman, Jacqueline L., Adibekian, Alexander, Hoover, Heather, Niessen, Sherry, Cravatt, Benjamin F., Shokat, Kevan M.

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Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action von Viader, Andreu, Blankman, Jacqueline L., Zhong, Peng, Liu, Xiaojie, Schlosburg, Joel E., Joslyn, Christopher M., Liu, Qing-Song, Tomarchio, Aaron J., Lichtman, Aron H., Selley, Dana E., Sim-Selley, Laura J., Cravatt, Benjamin F.

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A Functional Proteomic Strategy to Discover Inhibitors for Uncharacterized Hydrolases von Li, Weiwei, Blankman, Jacqueline L, Cravatt, Benjamin F

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The Serine Hydrolase ABHD6 Is a Critical Regulator of the Metabolic Syndrome von Thomas, Gwynneth, Betters, Jenna L., Lord, Caleb C., Brown, Amanda L., Marshall, Stephanie, Ferguson, Daniel, Sawyer, Janet, Davis, Matthew A., Melchior, John T., Blume, Lawrence C., Howlett, Allyn C., Ivanova, Pavlina T., Milne, Stephen B., Myers, David S., Mrak, Irina, Leber, Vera, Heier, Christoph, Taschler, Ulrike, Blankman, Jacqueline L., Cravatt, Benjamin F., Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Zimmermann, Robert, Brown, H. Alex, Brown, J. Mark

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Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling von Hoover, Heather S., Blankman, Jacqueline L., Niessen, Sherry, Cravatt, Benjamin F.

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Chemical probes of endocannabinoid metabolism von Blankman, Jacqueline L, Cravatt, Benjamin F

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Genetic deletion of monoacylglycerol lipase alters endocannabinoid‐mediated retrograde synaptic depression in the cerebellum von Zhong, Peng, Pan, Bin, Gao, Xiu‐ping, Blankman, Jacqueline L., Cravatt, Benjamin F., Liu, Qing‐song

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Activation of the endocannabinoid system by organophosphorus nerve agents von Blankman, Jacqueline L, Simon, Gabriel M, Nomura, Daniel K, Cravatt, Benjamin F, Fujioka, Kazutoshi, Issa, Roger S, Ward, Anna M, Casida, John E

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Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation von Nomura, Daniel K., Morrison, Bradley E., Blankman, Jacqueline L., Long, Jonathan Z., Kinsey, Steven G., Marcondes, Maria Cecilia G., Ward, Anna M., Hahn, Yun Kyung, Lichtman, Aron H., Conti, Bruno, Cravatt, Benjamin F.

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Selective inhibitors of SARM1 targeting an allosteric cysteine in the autoregulatory ARM domain von Feldman, Hannah C, Merlini, Elisa, Guijas, Carlos, DeMeester, Kristen E, Njomen, Evert, Kozina, Ellen M, Yokoyama, Minoru, Vinogradova, Ekaterina, Reardon, Holly T, Melillo, Bruno, Schreiber, Stuart L, Loreto, Andrea, Blankman, Jacqueline L, Cravatt, Benjamin F

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Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pa... von Ahn, Kay, Smith, Sarah E, Liimatta, Marya B, Beidler, David, Sadagopan, Nalini, Dudley, David T, Young, Tim, Wren, Paul, Zhang, Yanhua, Swaney, Steven, Van Becelaere, Keri, Blankman, Jacqueline L, Nomura, Daniel K, Bhattachar, Shobha N, Stiff, Cory, Nomanbhoy, Tyzoon K, Weerapana, Eranthie, Johnson, Douglas S, Cravatt, Benjamin F

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The fatty acid amide hydrolase (FAAH) inhibitor PF‐3845 acts in the nervous system to reverse LPS‐induced tactile allodynia in mice von Booker, Lamont, Kinsey, Steven G, Abdullah, Rehab A, Blankman, Jacqueline L, Long, Jonathan Z, Ezzili, Cyrine, Boger, Dale L, Cravatt, Benjamin F, Lichtman, Aron H

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Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators von Clapper, Jason R, Henry, Cassandra L, Niphakis, Micah J, Knize, Anna M, Coppola, Aundrea R, Simon, Gabriel M, Ngo, Nhi, Herbst, Rachel A, Herbst, Dylan M, Reed, Alex W, Cisar, Justin S, Weber, Olivia D, Viader, Andreu, Alexander, Jessica P, Cunningham, Mark L, Jones, Todd K, Fraser, Iain P, Grice, Cheryl A, Ezekowitz, R Alan B, O'Neill, Gary P, Blankman, Jacqueline L

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