Magnetic relaxation pathways in lanthanide single-molecule magnets von Blagg, Robin J., Ungur, Liviu, Tuna, Floriana, Speak, James, Comar, Priyanka, Collison, David, Wernsdorfer, Wolfgang, McInnes, Eric J. L., Chibotaru, Liviu F., Winpenny, Richard E. P.

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Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor von Khandelwal, Anuj, Kent, Caitlin N., Balch, Maurie, Peng, Shuxia, Mishra, Sanket J., Deng, Junpeng, Day, Victor W., Liu, Weiya, Subramanian, Chitra, Cohen, Mark, Holzbeierlein, Jeffery M., Matts, Robert, Blagg, Brian S. J.

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A first-in-class Polymerase Theta Inhibitor selectively targets Homologous-Recombination-Deficient Tumors von Zhou, Jia, Gelot, Camille, Pantelidou, Constantia, Li, Adam, Yücel, Hatice, Davis, Rachel E, Färkkilä, Anniina, Kochupurakkal, Bose, Syed, Aleem, Shapiro, Geoffrey I, Tainer, John A, Blagg, Brian S J, Ceccaldi, Raphael, D'Andrea, Alan D

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Hsp90 activator Aha1 drives production of pathological tau aggregates von Shelton, Lindsey B., Baker, Jeremy D., Zheng, Dali, Sullivan, Leia E., Solanki, Parth K., Webster, Jack M., Sun, Zheying, Sabbagh, Jonathan J., Nordhues, Bryce A., Koren, John, Ghosh, Suman, Blagg, Brian S. J., Blair, Laura J., Dickey, Chad A.

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Engineering an Antibiotic to Fight Cancer: Optimization of the Novobiocin Scaffold to Produce Anti-proliferative Agents von Zhao, Huiping, Donnelly, Alison C, Kusuma, Bhaskar R, Brandt, Gary E. L, Brown, Douglas, Rajewski, Roger A, Vielhauer, George, Holzbeierlein, Jeffrey, Cohen, Mark S, Blagg, Brian S. J

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Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding von Que, Nanette L. S, Crowley, Vincent M, Duerfeldt, Adam S, Zhao, Jinbo, Kent, Caitlin N, Blagg, Brian S. J, Gewirth, Daniel T

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Hsp90β inhibition upregulates interferon response and enhances immune checkpoint blockade therapy in murine tumors von Rahmy, Sharif, Mishra, Sanket J, Murphy, Sean, Blagg, Brian S J, Lu, Xin

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JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells von Walters, Z S, Villarejo-Balcells, B, Olmos, D, Buist, T W S, Missiaglia, E, Allen, R, Al-Lazikani, B, Garrett, M D, Blagg, J, Shipley, J

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Gambogic Acid, a Natural Product Inhibitor of Hsp90 von Davenport, Jason, Manjarrez, Jacob R, Peterson, Laura, Krumm, Brian, Blagg, Brian S. J, Matts, Robert L

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Inhibiting spinal cord-specific hsp90 isoforms reveals a novel strategy to improve the therapeutic index of opioid treatment von Duron, David I., Tanguturi, Parthasaradhireddy, Campbell, Christopher S., Chou, Kerry, Bejarano, Paul, Gabriel, Katherin A., Bowden, Jessica L., Mishra, Sanket, Brackett, Christopher, Barlow, Deborah, Houseknecht, Karen L., Blagg, Brian S. J., Streicher, John M.

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Pentametallic lanthanide-alkoxide square-based pyramids: high energy barrier for thermal relaxation in a holmium single molecule magnet von Blagg, Robin J, Tuna, Floriana, McInnes, Eric J L, Winpenny, Richard E P

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C-Terminal Heat Shock Protein 90 Inhibitor Decreases Hyperglycemia-induced Oxidative Stress and Improves Mitochondrial Bioenergetics in Sensory Neurons von Zhang, Liang, Zhao, Huiping, Blagg, Brian S. J, Dobrowsky, Rick T

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Click chemistry to probe Hsp90: Synthesis and evaluation of a series of triazole-containing novobiocin analogues von Peterson, Laura B., Blagg, Brian S.J.

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3-Arylcoumarin Derivatives Manifest Anti-proliferative Activity through Hsp90 Inhibition von Zhao, Huiping, Yan, Bin, Peterson, Laura B, Blagg, Brian S. J

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Identification and initial SAR of silybin: An Hsp90 inhibitor von Zhao, Huiping, Brandt, Gary E., Galam, Lakshmi, Matts, Robert L., Blagg, Brian S.J.

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The Development of Hsp90β-Selective Inhibitors to Overcome Detriments Associated with pan-Hsp90 Inhibition von Mishra, Sanket J, Liu, Weiya, Beebe, Kristin, Banerjee, Monimoy, Kent, Caitlin N, Munthali, Vitumbiko, Koren, John, Taylor, John A, Neckers, Leonard M, Holzbeierlein, Jeffrey, Blagg, Brian S. J

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Modulating molecular chaperones improves sensory fiber recovery and mitochondrial function in diabetic peripheral neuropathy von Urban, Michael J., Pan, Pan, Farmer, Kevin L., Zhao, Huiping, Blagg, Brian S.J., Dobrowsky, Rick T.

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Novel C‐terminal heat shock protein 90 inhibitors target breast cancer stem cells and block migration, self‐renewal, and epithelial–mesenchymal transition von Subramanian, Chitra, Grogan, Patrick T., Wang, Ton, Bazzill, Joseph, Zuo, Ang, White, Peter T., Kalidindi, Avinaash, Kuszynski, Dawn, Wang, Grace, Blagg, Brian S. J., Cohen, Mark S.

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Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma von Stothert, Andrew R., Suntharalingam, Amirthaa, Tang, Xiaolan, Crowley, Vincent M., Mishra, Sanket J., Webster, Jack M., Nordhues, Bryce A., Huard, Dustin J. E., Passaglia, Christopher L., Lieberman, Raquel L., Blagg, Brian S. J., Blair, Laura J., Koren, John, Dickey, Chad A.

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Protection against Aβ-induced neuronal damage by KU-32: PDHK1 inhibition as important target von Pal, Ranu, Hui, Dongwei, Menchen, Heather, Zhao, Huiping, Mozziconacci, Olivier, Wilkins, Heather, Blagg, Brian S J, Schöneich, Christian, Swerdlow, Russell H, Michaelis, Mary L, Michaelis, Elias K

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