The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design von Russell, Rupert J., Haire, Lesley F., Stevens, David J., Collins, Patrick J., Lin, Yi Pu, Blackburn, G. Michael, Hay, Alan J., Gamblin, Steven J., Skehel, John J.

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Thermokinetic profile of NDM-1 and its inhibition by small carboxylic acids von Wang, Qian, He, Yuan, Lu, Rui, Wang, Wen-Ming, Yang, Ke-Wu, Fan, Hai Ming, Jin, Yi, Blackburn, G Michael

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Nucleic Acids in Chemistry and Biology von Blackburn, G. Michael, Egli, Martin, Gait, Michael J, Watts, Jonathan K

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Structure and catalytic mechanism of the human histone methyltransferase SET7/9 von Xiao, Bing, Jing, Chun, Wilson, Jonathan R., Walker, Philip A., Vasisht, Nishi, Kelly, Geoff, Howell, Steven, Taylor, Ian A., Blackburn, G. Michael, Gamblin, Steven J.

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Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo von Ilyushin, Denis G., Smirnov, Ivan V., Belogurov, Alexey A., Dyachenko, Igor A., Zharmukhamedova, Tatiana lu, Novozhilova, Tatjana I., Bychikhin, Eugene A., Serebryakova, Marina V., Kharybin, Oleg N., Murashev, Arkadii N., Anikienko, Konstantin A., Nikolaev, Eugene N., Ponomarenko, Natalia A., Genkin, Dmitry D., Blackburn, G. Michael, Masson, Patrick, Gabibov, Alexander G.

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α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction von Jin, Yi, Bhattasali, Debabrata, Pellegrini, Erika, Forget, Stephanie M., Baxter, Nicola J., Cliff, Matthew J., Bowler, Matthew W., Jakeman, David L., Blackburn, G. Michael, Waltho, Jonathan P.

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Near attack conformers dominate β-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate von Griffin, Joanna L, Bowler, Matthew W, Baxter, Nicola J, Leigh, Katherine N, Dannatt, Hugh R. W, Hounslow, Andrea M, Blackburn, G. Michael, Webster, Charles Edwin, Cliff, Matthew J, Waltho, Jonathan P

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Anionic Charge Is Prioritized over Geometry in Aluminum and Magnesium Fluoride Transition State Analogs of Phosphoryl Transfer Enzymes von Baxter, Nicola J, Blackburn, G. Michael, Marston, James P, Hounslow, Andrea M, Cliff, Matthew J, Bermel, Wolfgang, Williams, Nicholas H, Hollfelder, Florian, Wemmer, David E, Waltho, Jonathan P

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Metal Fluorides as Analogues for Studies on Phosphoryl Transfer Enzymes von Jin, Yi, Richards, Nigel G., Waltho, Jonathan P., Blackburn, G. Michael

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Chiral phosphoproline-catalyzed asymmetric Michael addition of ketones to nitroolefins: an experimental and theoretical study von Zeng, Zhiping, Luo, Ping, Jiang, Yao, Liu, Yan, Tang, Guo, Xu, Pengxiang, Zhao, Yufen, Blackburn, G Michael

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A Trojan horse transition state analogue generated by MgF3− formation in an enzyme active site von Baxter, Nicola J, Olguin, Luis F, Golicnik, Marko, Feng, Guoqiang, Hounslow, Andrea M, Bermel, Wolfgang, Blackburn, G Michael, Hollfelder, Florian, Waltho, Jonathan P, Williams, Nicholas H

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Why did Nature select phosphate for its dominant roles in biology? von Bowler, Matthew W., Cliff, Matthew J., Waltho, Jonathan P., Blackburn, G. Michael

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Arginine Kinase Activates Arginine for Phosphorylation by Pyramidalization and Polarization von Falcioni, Fabio, Molt, Robert W., Jin, Yi, Waltho, Jonathan P., Hay, Sam, Richards, Nigel G. J., Blackburn, G. Michael

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Metal Fluorides: Tools for Structural and Computational Analysis of Phosphoryl Transfer Enzymes von Jin, Yi, Molt, Robert W., Blackburn, G. Michael

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Immunoglobulin Go: Synergy of Combinatorics for Catalysis von Smirnov, Ivan, Belogurov, Alexey, Golovin, Andrey, Stepanov, Alexey, Zhang, Hongkai, Blackburn, G. Michael, Gabibov, Alexander

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Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library von Cesaro-Tadic, Sandro, Lagos, Dimitrios, Honegger, Annemarie, Rickard, James H, Partridge, Lynda J, Blackburn, G Michael, Plückthun, Andreas

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Octahedral Trifluoromagnesate, an Anomalous Metal Fluoride Species, Stabilizes the Transition State in a Biological Motor von Ge, Mengyu, Molt, Robert W, Jenkins, Huw T, Blackburn, G. Michael, Jin, Yi, Antson, Alfred A

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Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers von Mokrushina, Yuliana A., Golovin, Andrey V., Smirnov, Ivan V., Chatziefthimiou, Spyros D., Stepanova, Anastasia V., Bobik, Tatyana V., Zalevsky, Arthur O., Zlobin, Alexander S., Konovalov, Kirill A., Terekhov, Stanislav S., Stepanov, Alexey V., Pipiya, Sofiya O., Shamborant, Olga G., Round, Ekaterina, Belogurov, Alexey A., Bourenkov, Gleb, Makarov, Alexander A., Wilmanns, Matthias, Xie, Jia, Blackburn, G. Michael, Gabibov, Alexander G., Lerner, Richard A.

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Evidence Supporting a cis-enediol-based Mechanism for Pyrococcus furiosus Phosphoglucose Isomerase von Berrisford, John M., Hounslow, Andrea M., Akerboom, Jasper, Hagen, Wilfred R., Brouns, Stan J.J., van der Oost, John, Murray, Iain A., Michael Blackburn, G., Waltho, Jonathan P., Rice, David W., Baker, Patrick J.

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Biochemical, Crystallographic, and Mutagenic Characterization of Hint, the AMP-Lysine Hydrolase, with Novel Substrates and Inhibitors von Krakowiak, Agnieszka, Pace, Helen C, Blackburn, G Michael, Adams, Martina, Mekhalfia, Abdelaziz, Kaczmarek, Renata, Baraniak, Janina, Stec, Wojciech J, Brenner, Charles

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