Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization von Klein, Florian, Diskin, Ron, Scheid, Johannes F., Gaebler, Christian, Mouquet, Hugo, Georgiev, Ivelin S., Pancera, Marie, Zhou, Tongqing, Incesu, Reha-Baris, Fu, Brooks Zhongzheng, Gnanapragasam, Priyanthi N.P., Oliveira, Thiago Y., Seaman, Michael S., Kwong, Peter D., Bjorkman, Pamela J., Nussenzweig, Michel C.

Volltext

Structural Insights on the Role of Antibodies in HIV-1 Vaccine and Therapy von West, Anthony P., Scharf, Louise, Scheid, Johannes F., Klein, Florian, Bjorkman, Pamela J., Nussenzweig, Michel C.

Volltext

SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies von Barnes, Christopher O., Jette, Claudia A., Abernathy, Morgan E., Dam, Kim-Marie A., Esswein, Shannon R., Gristick, Harry B., Malyutin, Andrey G., Sharaf, Naima G., Huey-Tubman, Kathryn E., Lee, Yu E., Robbiani, Davide F., Nussenzweig, Michel C., West, Anthony P., Bjorkman, Pamela J.

Volltext

Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice von Cohen, Alexander A, Gnanapragasam, Priyanthi N P, Lee, Yu E, Hoffman, Pauline R, Ou, Susan, Kakutani, Leesa M, Keeffe, Jennifer R, Wu, Hung-Jen, Howarth, Mark, West, Anthony P, Barnes, Christopher O, Nussenzweig, Michel C, Bjorkman, Pamela J

Volltext

Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies von Greaney, Allison J., Starr, Tyler N., Barnes, Christopher O., Weisblum, Yiska, Schmidt, Fabian, Caskey, Marina, Gaebler, Christian, Cho, Alice, Agudelo, Marianna, Finkin, Shlomo, Wang, Zijun, Poston, Daniel, Muecksch, Frauke, Hatziioannou, Theodora, Bieniasz, Paul D., Robbiani, Davide F., Nussenzweig, Michel C., Bjorkman, Pamela J., Bloom, Jesse D.

Volltext

Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env von Scharf, Louise, Wang, Haoqing, Gao, Han, Chen, Songye, McDowall, Alasdair W., Bjorkman, Pamela J.

Volltext

Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion von Wang, Haoqing, Barnes, Christopher O., Yang, Zhi, Nussenzweig, Michel C., Bjorkman, Pamela J.

Volltext

Few and far between: how HIV may be evading antibody avidity von Klein, Joshua S, Bjorkman, Pamela J

Volltext

LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells von Gu, Mingyu, LaJoie, Dollie, Chen, Opal S., von Appen, Alexander, Ladinsky, Mark S., Redd, Michael J., Nikolova, Linda, Bjorkman, Pamela J., Sundquist, Wesley I., Ullman, Katharine S., Frost, Adam

Volltext

Structural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120 von West, Anthony P, Diskin, Ron, Nussenzweig, Michel C, Bjorkman, Pamela J

Volltext

Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop von Wang, Haoqing, Cohen, Alexander A., Galimidi, Rachel P., Gristick, Harry B., Jensen, Grant J., Bjorkman, Pamela J.

Volltext

Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping von Treweek, Jennifer B, Chan, Ken Y, Flytzanis, Nicholas C, Yang, Bin, Deverman, Benjamin E, Greenbaum, Alon, Lignell, Antti, Xiao, Cheng, Cai, Long, Ladinsky, Mark S, Bjorkman, Pamela J, Fowlkes, Charless C, Gradinaru, Viviana

Volltext

Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers von Cohen, Alexander A, Yang, Zhi, Gnanapragasam, Priyanthi N P, Ou, Susan, Dam, Kim-Marie A, Wang, Haoqing, Bjorkman, Pamela J

Volltext

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies von Mouquet, Hugo, Scharf, Louise, Euler, Zelda, Liu, Yan, Eden, Caroline, Scheid, Johannes F., Halper-Stromberg, Ariel, Gnanapragasam, Priyanthi N. P., Spencer, Daniel I. R., Seaman, Michael S., Schuitemaker, Hanneke, Feizi, Ten, Nussenzweig, Michel C., Bjorkman, Pamela J.

Volltext

Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody von Schommers, Philipp, Gruell, Henning, Abernathy, Morgan E., Tran, My-Kim, Dingens, Adam S., Gristick, Harry B., Barnes, Christopher O., Schoofs, Till, Schlotz, Maike, Vanshylla, Kanika, Kreer, Christoph, Weiland, Daniela, Holtick, Udo, Scheid, Christof, Valter, Markus M., van Gils, Marit J., Sanders, Rogier W., Vehreschild, Jörg J., Cornely, Oliver A., Lehmann, Clara, Fätkenheuer, Gerd, Seaman, Michael S., Bloom, Jesse D., Bjorkman, Pamela J., Klein, Florian

Volltext

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques von Shingai, Masashi, Donau, Olivia K, Plishka, Ronald J, Buckler-White, Alicia, Mascola, John R, Nabel, Gary J, Nason, Martha C, Montefiori, David, Moldt, Brian, Poignard, Pascal, Diskin, Ron, Bjorkman, Pamela J, Eckhaus, Michael A, Klein, Florian, Mouquet, Hugo, Cetrulo Lorenzi, Julio Cesar, Gazumyan, Anna, Burton, Dennis R, Nussenzweig, Michel C, Martin, Malcolm A, Nishimura, Yoshiaki

Volltext

Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2 von Huang, Kuan-Ying A., Chen, Xiaorui, Mohapatra, Arpita, Nguyen, Hong Thuy Vy, Schimanski, Lisa, Tan, Tiong Kit, Rijal, Pramila, Vester, Susan K., Hills, Rory A., Howarth, Mark, Keeffe, Jennifer R., Cohen, Alexander A., Kakutani, Leesa M., Wu, Yi-Min, Shahed-Al-Mahmud, Md, Chou, Yu-Chi, Bjorkman, Pamela J., Townsend, Alain R., Ma, Che

Volltext

Peptidoglycan Production by an Insect-Bacterial Mosaic von Bublitz, DeAnna C., Chadwick, Grayson L., Magyar, John S., Sandoz, Kelsi M., Brooks, Diane M., Mesnage, Stéphane, Ladinsky, Mark S., Garber, Arkadiy I., Bjorkman, Pamela J., Orphan, Victoria J., McCutcheon, John P.

Volltext

Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike von Scharf, Louise, Scheid, Johannes F., Lee, Jeong Hyun, West, Anthony P., Chen, Courtney, Gao, Han, Gnanapragasam, Priyanthi N.P., Mares, René, Seaman, Michael S., Ward, Andrew B., Nussenzweig, Michel C., Bjorkman, Pamela J.

Volltext

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice von Klein, Florian, Halper-Stromberg, Ariel, Horwitz, Joshua A., Gruell, Henning, Scheid, Johannes F., Bournazos, Stylianos, Mouquet, Hugo, Spatz, Linda A., Diskin, Ron, Abadir, Alexander, Zang, Trinity, Dorner, Marcus, Billerbeck, Eva, Labitt, Rachael N., Gaebler, Christian, Marcovecchio, Paola M., Incesu, Reha-Baris, Eisenreich, Thomas R., Bieniasz, Paul D., Seaman, Michael S., Bjorkman, Pamela J., Ravetch, Jeffrey V., Ploss, Alexander, Nussenzweig, Michel C.

Volltext