Sorafenib Induces Pyroptosis in Macrophages and Triggers Natural Killer Cell–Mediated Cytotoxicity Against Hepatocellular Carcinoma von Hage, Carina, Hoves, Sabine, Strauss, Léanne, Bissinger, Stefan, Prinz, Ylva, Pöschinger, Thomas, Kiessling, Fabian, Ries, Carola H.

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Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity von Hoves, Sabine, Ooi, Chia-Huey, Wolter, Carsten, Sade, Hadassah, Bissinger, Stefan, Schmittnaegel, Martina, Ast, Oliver, Giusti, Anna M, Wartha, Katharina, Runza, Valeria, Xu, Wei, Kienast, Yvonne, Cannarile, Michael A, Levitsky, Hyam, Romagnoli, Solange, De Palma, Michele, Rüttinger, Dominik, Ries, Carola H

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Periostin Limits Tumor Response to VEGFA Inhibition von Keklikoglou, Ioanna, Kadioglu, Ece, Bissinger, Stefan, Langlois, Benoît, Bellotti, Axel, Orend, Gertraud, Ries, Carola H., De Palma, Michele

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301 OMX-0407, a highly potent SIK3 inhibitor, sensitizes tumor cells to apoptosis and eradicates tumors in combination with PD-1 inhibition von Hartl, Christina, Michels, Tillmann, Milde, Ronny, Klein, Vanessa, Beckhove, Philipp, Loferer, Hannes, Bissinger, Stefan

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60 Development of a gene signature to predict the anti-tumor response of the salt-inducible kinase (SIK) inhibitor OMX-0407 von Maser, Ilona-Petra, Lacher, Sonja, Stebegg, Marisa, Piras, Vincent, Kracher, Barbara, Quirin, Kai, Yule, Murray, Loferer, Hannes, Bissinger, Stefan

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Vaccine-induced CD8 T cells are redirected with peptide-MHC class I-IgG antibody fusion proteins to eliminate tumor cells in vivo von Fischer, Cornelia, Munks, Michael W., Hill, Ann B., Kroczek, Richard A., Bissinger, Stefan, Brand, Verena, Schmittnaegel, Martina, Imhof-Jung, Sabine, Hoffmann, Eike, Herting, Frank, Klein, Christian, Knoetgen, Hendrik

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Impact of selective anti-BMP9 treatment on tumor cells and tumor angiogenesis von Brand, Verena, Lehmann, Christian, Umkehrer, Christian, Bissinger, Stefan, Thier, Martina, de Wouters, Mariana, Raemsch, Romi, Jucknischke, Ute, Haas, Alexander, Breuer, Sebastian, Birzele, Fabian, Racek, Tomas, Reis, Marco, Lorenzon, Erica, Herting, Frank, Stürzl, Michael, Lorenz, Stefan, Kienast, Yvonne

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Abstract 6698: A first-in-class SIK3 inhibitor, OMX-0370, effectively inhibits tumor growth in syngeneic tumor models, as single agent, by abolishing tumor resistance to immune-der... von Michels, Tillmann, Bissinger, Stefan, Sennhenn, Peter, Loferer, Hannes, Freire, Catarina Martins, Reidell, Olivia, Meier-Ewert, Sebastian, Papadimitriou, Apollon, Beckhove, Philipp, Khandelwal, Nisit

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Abstract 953: Development of a predictive biomarker signature for the highly potent SIK3 inhibitor OMX-0407 von Maser, Ilona-Petra, Lacher, Sonja, Piras, Vincent, Kracher, Barbara, Zanziger, Kai, Yule, Murray, Loferer, Hannes, Bissinger, Stefan

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Abstract 3708: OMX-0407, a highly potent SIK3 inhibitor, sensitizes tumor cells to cell death and eradicates tumors in combination with PD-1 inhibition von Hartl, Christina, Maser, Ilona-Petra, Michels, Tillmann, Milde, Ronny, Klein, Vanessa, Beckhove, Philipp, Khandelwal, Nisit, Loferer, Hannes, Bissinger, Stefan

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COMBINATION THERAPIES BASED ON PD-1 INHIBITORS AND SIK3 INHIBITORS von LOFERER, Hannes, BISSINGER, Stefan

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COMBINATION THERAPIES BASED ON PD-1 INHIBITORS AND SIK3 INHIBITORS von LOFERER, Hannes, BISSINGER, Stefan

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SIK3 INHIBITORS FOR TREATING DISEASES RESISTANT TO DEATH RECEPTOR SIGNALLING von MASER, Petra, BISSINGER, Stefan

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COMBINATION THERAPIES BASED ON PD-1 INHIBITORS AND SIK3 INHIBITORS von LOFERER, Hannes, BISSINGER, Stefan

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SIK3 INHIBITORS FOR TREATING DISEASES RESISTANT TO DEATH RECEPTOR SIGNALLING von MASER, Petra, BISSINGER, Stefan

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COMBINATION THERAPIES BASED ON PD-1 INHIBITORS AND SIK3 INHIBITORS von LOFERER, Hannes, BISSINGER, Stefan

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HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF von KHANDELWAL, Nisit, BANCROFT, David, SENNHENN, Peter, LOFERER, Hannes, MICHELS, Tillmann, BISSINGER, Stefan

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HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF von KHANDELWAL, Nisit, BANCROFT, David, SENNHENN, Peter, LOFERER, Hannes, MICHELS, Tillmann, BISSINGER, Stefan

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HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF von KHANDELWAL, Nisit, BANCROFT, David, SENNHENN, Peter, LOFERER, Hannes, MICHELS, Tillmann, BISSINGER, Stefan

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ANTIBODIES BINDING IGV OF IGSF11 (VSIG3) AND USES THEREOF von MICHELS, Tillman, KHANDELWAL, Nisit, ZANTOW, Jonas, REGULA, Joerg Thomas, GENSSLER, Sabrina, URLINGER, Stefanie, BRAENDLE, Simone, AIGNER, Maximilian, BISSINGER, Stefan

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