Mitochondrial uncouplers induce proton leak by activating AAC and UCP1 von Bertholet, Ambre M., Natale, Andrew M., Bisignano, Paola, Suzuki, Junji, Fedorenko, Andriy, Hamilton, James, Brustovetsky, Tatiana, Kazak, Lawrence, Garrity, Ryan, Chouchani, Edward T., Brustovetsky, Nickolay, Grabe, Michael, Kirichok, Yuriy

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Cilia-Associated Oxysterols Activate Smoothened von Raleigh, David R., Sever, Navdar, Choksi, Pervinder K., Sigg, Monika Abedin, Hines, Kelly M., Thompson, Bonne M., Elnatan, Daniel, Jaishankar, Priyadarshini, Bisignano, Paola, Garcia-Gonzalo, Francesc R., Krup, Alexis Leigh, Eberl, Markus, Byrne, Eamon F.X., Siebold, Christian, Wong, Sunny Y., Renslo, Adam R., Grabe, Michael, McDonald, Jeffrey G., Xu, Libin, Beachy, Philip A., Reiter, Jeremy F.

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Cilia-enriched oxysterol 7β,27-DHC is required for polycystin ion channel activation von Ha, Kodaji, Mundt-Machado, Nadine, Bisignano, Paola, Pinedo, Aide, Raleigh, David R., Loeb, Gabriel, Reiter, Jeremy F., Cao, Erhu, Delling, Markus

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Inhibitor binding mode and allosteric regulation of Na+-glucose symporters von Bisignano, Paola, Ghezzi, Chiara, Jo, Hyunil, Polizzi, Nicholas F., Althoff, Thorsten, Kalyanaraman, Chakrapani, Friemann, Rosmarie, Jacobson, Matthew P., Wright, Ernest M., Grabe, Michael

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A systems-biology approach to molecular machines: Exploration of alternative transporter mechanisms von George, August, Bisignano, Paola, Rosenberg, John M, Grabe, Michael, Zuckerman, Daniel M

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A kinetic mechanism for enhanced selectivity of membrane transport von Bisignano, Paola, Lee, Michael A, George, August, Zuckerman, Daniel M, Grabe, Michael, Rosenberg, John M

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Protonation state of glutamate 73 regulates the formation of a specific dimeric association of mVDAC1 von Bergdoll, Lucie A., Lerch, Michael T., Patrick, John W., Belardo, Kendrick, Altenbach, Christian, Bisignano, Paola, Laganowsky, Arthur, Grabe, Michael, Hubbell, Wayne L., Abramson, Jeff

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Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site von Wahlgren, Weixiao Y., Dunevall, Elin, North, Rachel A., Paz, Aviv, Scalise, Mariafrancesca, Bisignano, Paola, Bengtsson-Palme, Johan, Goyal, Parveen, Claesson, Elin, Caing-Carlsson, Rhawnie, Andersson, Rebecka, Beis, Konstantinos, Nilsson, Ulf J., Farewell, Anne, Pochini, Lorena, Indiveri, Cesare, Grabe, Michael, Dobson, Renwick C. J., Abramson, Jeff, Ramaswamy, S., Friemann, Rosmarie

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Conformational transitions of the sodium-dependent sugar transporter, vSGLT von Paz, Aviv, Claxton, Derek P., Kumar, Jay Prakash, Kazmier, Kelli, Bisignano, Paola, Sharma, Shruti, Nolte, Shannon A., Liwag, Terrin M., Nayak, Vinod, Wright, Ernest M., Grabe, Michael, Mchaourab, Hassane S., Abramson, Jeff

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MerlinS13 phosphorylation regulates meningioma Wnt signaling and magnetic resonance imaging features von Eaton, Charlotte D., Avalos, Lauro, Liu, S. John, Chen, Zhenhong, Zakimi, Naomi, Casey-Clyde, Tim, Bisignano, Paola, Lucas, Calixto-Hope G., Stevenson, Erica, Choudhury, Abrar, Vasudevan, Harish N., Magill, Stephen T., Young, Jacob S., Krogan, Nevan J., Villanueva-Meyer, Javier E., Swaney, Danielle L., Raleigh, David R.

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Stochastic steps in secondary active sugar transport von Adelman, Joshua L., Ghezzi, Chiara, Bisignano, Paola, Loo, Donald D. F., Choe, Seungho, Abramson, Jeff, Rosenberg, John M., Wright, Ernest M., Grabe, Michael

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PLI: a web-based tool for the comparison of protein-ligand interactions observed on PDB structures von Gallina, Anna Maria, Bisignano, Paola, Bergamino, Maurizio, Bordo, Domenico

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Molecular dynamics analysis of the wild type and dF508 mutant structures of the human CFTR–nucleotide binding domain 1 von Bisignano, Paola, Moran, Oscar

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CSIG-22. CANCER-ASSOCIATED MISSENSE SINGLE NUCLEOTIDE VARIANTS REGULATE THE STABILITY AND SUBCELLULAR LOCALIZATION OF NF2/MERLIN von Eaton, Charlotte, Bisignano, Paola, Raleigh, David

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Mechanistic Insights into the Allosteric Modulation of Opioid Receptors by Sodium Ions von Shang, Yi, LeRouzic, Valerie, Schneider, Sebastian, Bisignano, Paola, Pasternak, Gavril W, Filizola, Marta

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Mitochondrial uncouplers induce proton leak by activating AAC and UCP1 von Grabe, Michael, Natale, Andrew M., Bertholet, Ambre M., Bisignano, Paola, Kirichok, Yuriy V., Suzuki, Junji

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Quantitative Simulations of Alternating Access in Sodium-Solute Symporters von Bisignano, Paola, Capponi, Sara, Rosenberg, John M., Grabe, Michael

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Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE‑1 and GSK-3β Inhibitors von Di Martino, Rita Maria Concetta, De Simone, Angela, Andrisano, Vincenza, Bisignano, Paola, Bisi, Alessandra, Gobbi, Silvia, Rampa, Angela, Fato, Romana, Bergamini, Christian, Perez, Daniel I, Martinez, Ana, Bottegoni, Giovanni, Cavalli, Andrea, Belluti, Federica

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Conformational Landscape of Sodium Glucose Transporters von Bisignano, Paola, Capponi, Sara, Rosenberg, John M., Grabe, Michael

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Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice von Tolani, Bhairavi, Celli, Anna, Yao, Yanmin, Tan, Yong Zi, Fetter, Richard, Liem, Christina R., de Smith, Adam J., Vasanthakumar, Thamiya, Bisignano, Paola, Cotton, Adam D., Seiple, Ian B., Rubinstein, John L., Jost, Marco, Weissman, Jonathan S.

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