Novel bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human Immunodeficiency Virus I... von KOH, Yasuhiro, NAKATA, Hirotomo, VOLARATH, Patra, GADDIS, Laquasha, HARRISON, Robert W, WEBER, Irene T, GHOSH, Arun K, MITSUYA, Hiroaki, MAEDA, Kenji, OGATA, Hiromi, BILCER, Geoffrey, DEVASAMUDRAM, Thippeswamy, KINCAID, John F, BOROSS, Peter, WANG, Yuan-Fang, TIE, Yunfeng

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Structure-Based Design:  Potent Inhibitors of Human Brain Memapsin 2 (β-Secretase) von Ghosh, Arun K, Bilcer, Geoffrey, Harwood, Cynthia, Kawahama, Reiko, Shin, Dongwoo, Hussain, Khaja Azhar, Hong, Lin, Loy, Jeffrey A, Nguyen, Chan, Koelsch, Gerald, Ermolieff, Jacques, Tang, Jordan

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Structure-based design of cycloamide–urethane-derived novel inhibitors of human brain memapsin 2 (β-secretase) von Ghosh, Arun K., Devasamudram, Thippeswamy, Hong, Lin, DeZutter, Christopher, Xu, Xiaoming, Weerasena, Vajira, Koelsch, Gerald, Bilcer, Geoffrey, Tang, Jordan

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A stereoselective synthesis of (+)-boronolide von Ghosh, Arun K, Bilcer, Geoffrey

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Tartaric Acid and Tartrates in the Synthesis of Bioactive Molecules von Ghosh, Arun K., Koltun, Elena S., Bilcer, Geoffrey

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Real-time Microdialysis for aβ Inhibition And Pk/pd Analysis in A Nonhuman Primate Model: In Vivo Efficacy of a Bace-1 Inhibitor von Yu, Jeremy, Koelsch, Gerald, Li, Aiqun, Turner, Robert T, Bilcer, Geoffrey M, Miyake, Akira, Hamakawa, Nozomu, Terashita, Shigeyuki, Matsuoka, Nobuya, Hey, John A

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In vivo efficacy of BACE-1 inhibitor CTS21166 (ASP1702) in rat CNS compartments von Yu, Jeremy, Koelsch, Gerald, Li, Aiqun, Turner, Robert T, Bilcer, Geoffrey M, Grove, Carl, Hsu, Henry H, Shitaka, Yoshitsugu, Hamakawa, Nozomu, Terashita, Shigeyuki, Matsuoka, Nobuya, Tang, Jordan, Ghosh, Arun K, Hey, John A

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Structure-based design, synthesis and biological evaluation of novel β-secretase inhibitors containing a pyrazole or thiazole moiety as the P3 ligand von Ghosh, Arun K., Brindisi, Margherita, Yen, Yu-Chen, Xu, Xiaoming, Huang, Xiangping, Devasamudram, Thippeswamy, Bilcer, Geoffrey, Lei, Hui, Koelsch, Gerald, Mesecar, Andrew D., Tang, Jordan

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The Microtubule Stabilizing Agent Laulimalide Does Not Bind in the Taxoid Site, Kills Cells Resistant to Paclitaxel and Epothilones, and May Not Require Its Epoxide Moiety for Acti... von Pryor, Donald E, O'Brate, Aurora, Bilcer, Geoffrey, Díaz, J. Fernando, Wang, Yuefang, Wang, Yong, Kabaki, Mikio, Jung, M. Katherine, Andreu, José M, Ghosh, Arun K, Giannakakou, Paraskevi, Hamel, Ernest

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APN0417: A potent and efficacious α7 nAChR positive allosteric modulator von Dasse, Olivier, Bilcer, Geoffrey, Putman, David, Ng, Raymond, Gee, Kelvin, Stevens, Karen E., Tran, Minhtam, Johnstone, Tim, Yoshimura, Ryan F., Koelsch, Gerald, Kelly, Terence A.

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Design, Synthesis, and X-ray Structure of Potent Memapsin 2 (β-Secretase) Inhibitors with Isophthalamide Derivatives as the P2 -P3-Ligands von Ghosh, Arun K, Kumaragurubaran, Nagaswamy, Hong, Lin, Kulkarni, Sarang S, Xu, Xiaoming, Chang, Wanpin, Weerasena, Vajira, Turner, Robert, Koelsch, Gerald, Bilcer, Geoffrey, Tang, Jordan

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Syntheses of FDA Approved HIV Protease Inhibitors von Ghosh, Arun K., Bilcer, Geoffrey, Schiltz, Gary

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In vivo inhibition of Aβ production by memapsin 2 (β‐secretase) inhibitors von Chang, Wan‐Pin, Koelsch, Gerald, Wong, Stephen, Downs, Deborah, Da, Huining, Weerasena, Vajira, Gordon, Brian, Devasamudram, Thippeswamy, Bilcer, Geoffrey, Ghosh, Arun K., Tang, Jordan

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APN1125: A clinical stage α7 nicotinic acetylcholine receptor partial agonist von Koelsch, Gerald, Detke, Michael J., Stevens, Karen E., Meltzer, Leonard T., Terry, Alvin V., Callahan, Patrick M., Yoshimura, Ryan F., Bilcer, Geoffrey, Anderson, Paul C., Ng, John, Ng, Raymond, Kelly, Terence A.

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Design, Synthesis and X-ray Structure of Protein−Ligand Complexes:  Important Insight into Selectivity of Memapsin 2 (β-Secretase) Inhibitors von Ghosh, Arun K, Kumaragurubaran, Nagaswamy, Hong, Lin, Lei, Hui, Hussain, Khaja Azhar, Liu, Chun-Feng, Devasamudram, Thippeswamy, Weerasena, Vajira, Turner, Robert, Koelsch, Gerald, Bilcer, Geoffrey, Tang, Jordan

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P4‐373: APN1125: A NOVEL A7 NICOTINIC ACETYLCHOLINE RECEPTOR PARTIAL AGONIST von Koelsch, Gerald, Meltzer, Leonard T., Yoshimura, Ryan F., Terry, Alvin V., Callahan, Patrick M., Bilcer, Geoffrey, Ng, John, Ng, Raymond, Gee, Kelvin W., Kelly, Terence A.

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THERANOSTIC COMPOUNDS TARGETING GRANZYME B von KRONAUGE, James, BILCER, Geoffrey Malcolm

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THERANOSTIC COMPOUNDS TARGETING GRANZYME B von KRONAUGE, James, BILCER, Geoffrey Malcolm

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APN1125: A NOVEL A7 NICOTINIC ACETYLCHOLINE RECEPTOR PARTIAL AGONIST von Koelsch, Gerald, Meltzer, Leonard T, Yoshimura, Ryan F, Terry, Alvin V, Callahan, Patrick M, Bilcer, Geoffrey, Ng, John, Ng, Raymond, Gee, Kelvin W, Kelly, Terence A

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GRANZYME B DIRECTED IMAGING AND THERAPY von BILCER, Geoffrey, KELLY, Terence

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