Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success von Lovering, Frank, Bikker, Jack, Humblet, Christine

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Kinase Domain Mutations in Cancer: Implications for Small Molecule Drug Design Strategies von Bikker, Jack A, Brooijmans, Natasja, Wissner, Allan, Mansour, Tarek S

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Imputation of sensory properties using deep learning von Mahmoud, Samar, Irwin, Benedict, Chekmarev, Dmitriy, Vyas, Shyam, Kattas, Jeff, Whitehead, Thomas, Mansley, Tamsin, Bikker, Jack, Conduit, Gareth, Segall, Matthew

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Synthesis and pharmacological evaluation of aminopyrimidine series of 5-HT1A partial agonists von Dounay, Amy B, Barta, Nancy S, Bikker, Jack A, Borosky, Susan A, Campbell, Brian M, Crawford, Terry, Denny, Lynne, Evans, Lori M, Gray, David L, Lee, Pil, Lenoir, Edward A, Xu, Wenjian

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PF-06804103, A Site-specific Anti-HER2 Antibody–Drug Conjugate for the Treatment of HER2-expressing Breast, Gastric, and Lung Cancers von Graziani, Edmund I., Sung, Matthew, Ma, Dangshe, Narayanan, Bitha, Marquette, Kimberly, Puthenveetil, Sujiet, Tumey, L. Nathan, Bikker, Jack, Casavant, Jeffrey, Bennett, Eric M., Charati, Manoj B., Golas, Jonathon, Hosselet, Christine, Rohde, Cynthia M., Hu, George, Guffroy, Magali, Falahatpisheh, Hadi, Finkelstein, Martin, Clark, Tracey, Barletta, Frank, Tchistiakova, Lioudmila, Lucas, Judy, Rosfjord, Edward, Loganzo, Frank, O'Donnell, Christopher J., Gerber, Hans-Peter, Sapra, Puja

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Design and biological evaluation of non-peptide analogues of omega-conotoxin MVIIA von MENZLER, S, BIKKER, J. A, SUMAN-CHAUHAN, N, HORWELL, D. C

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Site Selection: a Case Study in the Identification of Optimal Cysteine Engineered Antibody Drug Conjugates von Tumey, L. Nathan, Li, Fengping, Rago, Brian, Han, Xiaogang, Loganzo, Frank, Musto, Sylvia, Graziani, Edmund I., Puthenveetil, Sujiet, Casavant, Jeffrey, Marquette, Kimberly, Clark, Tracey, Bikker, Jack, Bennett, Eric M., Barletta, Frank, Piche-Nicholas, Nicole, Tam, Amy, O’Donnell, Christopher J., Gerber, Hans Peter, Tchistiakova, Lioudmila

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Synthesis of a non-peptide analogue of omega-conotoxin MVIIA von Menzler, Stefan, Bikker, Jack A, Horwell, David C

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Direct Oxa-Pictet−Spengler Cyclization to the Natural (3a,5)-trans-Stereochemistry in the Syntheses of (+)-7-Deoxyfrenolicin B and (+)-7-Deoxykalafungin von Eid, Clark N, Shim, Jaechul, Bikker, Jack, Lin, Melissa

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Development of QSAR models for microsomal stability: identification of good and bad structural features for rat, human and mouse microsomal stability von Hu, Yongbo, Unwalla, Ray, Denny, R. Aldrin, Bikker, Jack, Di, Li, Humblet, Christine

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G-Protein Coupled Receptors:  Models, Mutagenesis, and Drug Design von Bikker, Jack Andrew, Trumpp-Kallmeyer, Susanne, Humblet, Christine

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A structural informatics approach to mine kinase knowledge bases von Brooijmans, Natasja, Mobilio, Dominick, Walker, Gary, Nilakantan, Ramaswamy, Denny, Rajiah A., Feyfant, Eric, Diller, David, Bikker, Jack, Humblet, Christine

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A structural information approach to mine kinase knowledge bases von BROOIJMANS, Natasja, MOBILIO, Dominick, WALKER, Gary, NILAKANTAN, Ramaswamy, DENNY, Rajiah A, FEYFANT, Eric, DILLER, David, BIKKER, Jack, HUMBLET, Christine

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Discovery and characterization of novel potent PARP-1 inhibitors endowed with neuroprotective properties: From TIQ-A to HYDAMTIQ von Pellicciari, Roberto, Camaioni, Emidio, Gilbert, Adam M., Macchiarulo, Antonio, Bikker, Jack A., Shah, Falgun, Bard, Joel, Costantino, Gabriele, Gioiello, Antimo, Robertson, Graeme M., Sabbatini, Paola, Venturoni, Francesco, Liscio, Paride, Carotti, Andrea, Bellocchi, Daniele, Cozzi, Andrea, Wood, Andrew, Gonzales, Cathleen, Zaleska, Margaret M., Ellingboe, John W., Moroni, Flavio

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Synthesis and pharmacological evaluation of aminopyrimidine series of 5-HT 1A partial agonists von Dounay, Amy B., Barta, Nancy S., Bikker, Jack A., Borosky, Susan A., Campbell, Brian M., Crawford, Terry, Denny, Lynne, Evans, Lori M., Gray, David L., Lee, Pil, Lenoir, Edward A., Xu, Wenjian

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Imputation of sensory properties using deep learning von Mahmoud, Samar, Irwin, Benedict, Chekmarev, Dmitriy, Vyas, Shyam, Kattas, Jeff, Whitehead, Thomas, Mansley, Tamsin, Bikker, Jack, Conduit, Gareth, Segall, Matthew

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Single domain binding molecule von Steven, John, Calabro, Valerie, Tchistiakova, Lioudmila, Bikker, Jack, Barelle, Caroline, Kovalenko, Oleg, Muller, Mischa Roland, Olland, Andrea

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SINGLE DOMAIN BINDING MOLECULE von STEVEN, John, TCHISTIAKOVA, Lioudmila, OLLAND, Andrea, BARELLE, Caroline, BIKKER, Jack A, MÜLLER, Mischa Roland, CALABRO, Valerie, KOVALENKO, Oleg

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Engineered antibody constant regions for site-specific conjugation and methods and uses therefor von Tchistiakova, Lioudmila, Calabro, Valerie, Bikker, Jack, Tumey, L. Nathan, Marquette, Kimberly, Bennett, Eric, Graziani, Edmund

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SINGLE DOMAIN BINDING MOLECULE von STEVEN, John, TCHISTIAKOVA, Lioudmila, OLLAND, Andrea, BARELLE, Caroline, BIKKER, Jack A, MÜLLER, Mischa Roland, CALABRO, Valerie, KOVALENKO, Oleg

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