Discovery of 2-Hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123):  A Potent, Orally Bioavailable CXCR2/CXCR1... von Dwyer, Michael P, Yu, Younong, Chao, Jianping, Aki, Cynthia, Chao, Jianhua, Biju, Purakkattle, Girijavallabhan, Viyyoor, Rindgen, Diane, Bond, Richard, Mayer-Ezel, Rosemary, Jakway, James, Hipkin, R. William, Fossetta, James, Gonsiorek, Waldemar, Bian, Hong, Fan, Xuedong, Terminelli, Carol, Fine, Jay, Lundell, Daniel, Merritt, J. Robert, Rokosz, Laura L, Kaiser, Bernd, Li, Ge, Wang, Wei, Stauffer, Tara, Ozgur, Lynne, Baldwin, John, Taveras, Arthur G

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Discovery of MK-8318, a Potent and Selective CRTh2 Receptor Antagonist for the Treatment of Asthma von Huang, Xianhai, Brubaker, Jason, Zhou, Wei, Biju, Purakkattle J., Xiao, Li, Shao, Ning, Huang, Ying, Dong, Li, Liu, Zhidan, Bitar, Rema, Buevich, Alexei, Jung, Joon, Peterson, Scott L., Butcher, John W., Close, Joshua, Martinez, Michelle, MacCoss, Rachel N., Zhang, Hongjun, Crawford, Scott, McCormick, Kevin D., Aslanian, Robert, Nargund, Ravi, Correll, Craig, Gervais, Francois, Qiu, Hongchen, Yang, Xiaoxin, Garlisi, Charles, Rindgen, Diane, Maloney, Kevin M., Siliphaivanh, Phieng, Palani, Anandan

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A new synthesis of 3,4-disubstituted 1,2,5-thiadiazoles von Biju, Purakkattle, Yu, Younong

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Synthesis of novel anti-inflammatory steroidal macrocycles using ring closing metathesis reaction von Biju, Purakkattle, Bitar, Rema, Lim, Yeon-Hee, Wang, Ying, Berlin, Michael, Aslanian, Robert, McCormick, Kevin

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Discovery of aminoquinazoline derivatives as human A(2A) adenosine receptor antagonists von Zhou, Gang, Aslanian, Robert, Gallo, Gioconda, Khan, Tanweer, Kuang, Rongze, Purakkattle, Biju, De Ruiz, Manuel, Stamford, Andrew, Ting, Pauline, Wu, Heping, Wang, Hongwu, Xiao, Dong, Yu, Tao, Zhang, Yonglian, Mullins, Deborra, Hodgson, Robert

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Discovery of aminoquinazoline derivatives as human A sub(2A) adenosine receptor antagonists von Zhou, Gang, Aslanian, Robert, Gallo, Gioconda, Khan, Tanweer, Kuang, Rongze, Purakkattle, Biju, Ruiz, Manuel De, Stamford, Andrew, Ting, Pauline, Wu, Heping, Wang, Hongwu, Xiao, Dong, Yu, Tao, Zhang, Yonglian, Mullins, Deborra, Hodgson, Robert

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Steroidal C-21 mercapto derivatives as dissociated steroids: Discovery of an inhaled dissociated steroid von Biju, Purakkattle, McCormick, Kevin, Aslanian, Robert, Berlin, Michael, Solomon, Daniel, Chapman, Richard, McLeod, Robbie, Prelusky, Daniel, Eckel, Stephen, Kelly, George, Natiello, Michelle, House, Aileen, Fernandez, Xiomara, Bitar, Rema, Phillips, Jonathan, Anthes, John

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C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists von Chao, Jianhua, Taveras, Arthur G., Chao, Jianping, Aki, Cynthia, Dwyer, Michael, Yu, Younong, Purakkattle, Biju, Rindgen, Diane, Jakway, James, Hipkin, William, Fosetta, James, Fan, Xuedong, Lundell, Daniel, Fine, Jay, Minnicozzi, Michael, Phillips, Jonathan, Merritt, J. Robert

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3,4-Diamino-1,2,5-thiadiazole as potent and selective CXCR2 antagonists von Biju, Purakkattle, Taveras, Arthur G., Yu, Younong, Zheng, Junying, Hipkin, R. William, Fossetta, James, Fan, Xuedong, Fine, Jay, Lundell, Daniel

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Steroidal C-21 heteroaryl thioethers (Part 2): Discovery of orally bioavailable selective glucocorticoid receptor modulators (dissociated steroids) von Biju, Purakkattle, McCormick, Kevin, Aslanian, Robert, Berlin, Michael, Solomon, Daniel, Wang, Hongwu, Lee, Yoon Joo, Bitar, Rema, Prelusky, Daniel, Mcleod, Robbie, Jia, Yanlin, Fernandez, Xiomora, Eckel, Stephen, House, Aileen, Lieber, Gissela, Jimenez, Johanna, Kelly, George, Chapman, Richard, Phillips, Jonathan, Anthes, John

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ChemInform Abstract: New Methodology for the Synthesis of α,α-Difluoroketones von Biju, Purakkattle

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NOVEL COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS von GUO, Liangqin, ACHAB, Abdelghani, DENG, Yongqi, MCGOWAN, Meredeth, A, HAN, Yongxin, SCIAMMETTA, Nunzio, ZHANG, Hongjun, FRADERA, Xavier, KOZLOWSKI, Joseph, LIU, Kun, HE, Shuwen, BIJU, Purakkattle, PU, Qinglin, KURUKULASURIYA, Ravi, ZHAO, Hua

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A New Synthesis of 3,4-Disubstituted 1,2,5-Thiadiazoles von Biju, Purakkattle, Yu, Younong

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5,6-di-substituted oxadiazolopyrazines and thiadiazolopyrazines as CXC-chemokine receptor ligands von BIJU PURAKKATTLE J

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5,6-di-substituted oxadiazolopyrazines and thiadiazolopyrazines as CXC-chemokine receptor ligands von Biju, Purakkattle J

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5,6-DI-SUBSTITUTED OXADIAZOLOPYRAZINES AND THIADIAZOLOPYRAZINES AS CXC-CHEMOKINE RECEPTOR LIGANDS von PURAKKATTLE, BIJU, J

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Di-substituted oxadiazoles as CXC-chemokine receptor ligands von Biju, Purakkattle J

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NOVEL TRICYCLIC COMPOUNDS AS INHIBITORS OF MUTANT IDH ENZYMES von HUANG, Xianhai, LI, Bing, BIFTU, Tesfaye, HUANG, Chunhui, BIJU, Purakkattle, BOGEN, Stephane, L, HONG, Qingmei, PARK, Min, K, WITTER, David, J, SLOMAN, David, L

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Substituted n′-hydroxycarbamimidoyl-1,2,5-oxadiazole compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors von Li, Guoqing, Achab, Abdelghani, Li, Derun, Yu, Wensheng, Shi, Zhi-Cai, Zhang, Hongjun, Guo, Liangqin, He, Shuwen, Liu, Kun, Deng, Yongqi, Han, Yongxin, Fradera, Xavier, Kozlowski, Joseph, Biju, Purakkattle, Pu, Qinglin, Cernak, Timothy A

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ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS von WANG, Bowei, PIO, Barbara, CHOBANIAN, Harry, BLIZZARD, Timothy, SZEWCZYK, Jason, W, PARKER, Dann, HAGMANN, William K, TIAN, Lili, LIN, Linus, S, LI, Bing, LV, Ying, GUDE, Candido, DANG, Qun, BIJU, Purakkattle, HU, Bin, ZHANG, Zaihong, JOSIEN, Hubert, CUI, Mingxiang, CHEN, Zhengxia, DAI, Meibi, NARGUND, Ravi, P

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