Silencing of the miR-17∼92 Cluster Family Inhibits Medulloblastoma Progression von MURPHY, Brian L, OBAD, Susanna, BIHANNIC, Laure, AYRAULT, Olivier, ZINDY, Frederique, KAUPPINEN, Sakari, ROUSSEL, Martine F

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Pemetrexed and Gemcitabine as Combination Therapy for the Treatment of Group3 Medulloblastoma von Morfouace, Marie, Shelat, Anang, Jacus, Megan, Freeman, Burgess B., Turner, David, Robinson, Sarah, Zindy, Frederique, Wang, Yong-Dong, Finkelstein, David, Ayrault, Olivier, Bihannic, Laure, Puget, Stephanie, Li, Xiao-Nan, Olson, James M., Robinson, Giles W., Guy, R. Kiplin, Stewart, Clinton F., Gajjar, Amar, Roussel, Martine F.

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ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas von Grausam, Katie B, Dooyema, Samuel D R, Bihannic, Laure, Premathilake, Hasitha, Morrissy, A Sorana, Forget, Antoine, Schaefer, Amanda M, Gundelach, Justin H, Macura, Slobodan, Maher, Diane M, Wang, Xin, Heglin, Alex H, Ge, Xijin, Zeng, Erliang, Puget, Stephanie, Chandrasekar, Indra, Surendran, Kameswaran, Bram, Richard J, Schüller, Ulrich, Talyor, Michael D, Ayrault, Olivier, Zhao, Haotian

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Insights into cerebellar development and medulloblastoma von Bihannic, Laure, Ayrault, Olivier

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MEDB-82. Exploring cell-cell communication networks in medulloblastoma using single-cell genomics von Gabler, Lisa, Gojo, Johannes, Smith, Kyle S, Bihannic, Laure, Filbin, Mariella G, Northcott, Paul A, Berger, Walter, Hovestadt, Volker

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Impact of the COVID‐19 pandemic on pediatric oncology providers globally: A mixed‐methods study von Sniderman, Elizabeth R., Graetz, Dylan E., Agulnik, Asya, Ranadive, Radhikesh, Vedaraju, Yuvanesh, Chen, Yichen, Devidas, Meenakshi, Chantada, Guillermo L., Hessissen, Laila, Dalvi, Rashmi, Pritchard‐Jones, Kathy, Rodriguez‐Galindo, Carlos, Moreira, Daniel C., Bolous, Nancy S., Haidar, Cyrine E., Bihannic, Laure, Sa da Bandeira, Diana, Wang, Jade Xiaoqing, Li, Dongfang, Graca, Flavia, Vasilyeva, Aksana, Lesmana, Harry

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EPCO-26. INTEGRATIVE MULTI-OMICS IDENTIFIES CONVERGING DEVELOPMENTAL ORIGINS OF DISTINCT MEDULLOBLASTOMA SUBGROUPS von Smith, Kyle, Bihannic, Laure, Gudenas, Brian, Gao, Qingsong, Haldipur, Parthiv, Hovestadt, Volker, Iskusnykh, Igor, Chizhikov, Viktor, Deng, Mei, Glass, Ian, Robinson, Giles, Orr, Brent, Patay, Zoltan, Aldinger, Kimberly, Millen, Kathleen, Northcott, Paul

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MEDB-78. Unified rhombic lip origins of Group 3 and Group 4 medulloblastoma von Smith, Kyle, Bihannic, Laure, Gudenas, Brian, Gao, Qingsong, Haldipur, Parthiv, Tao, Ran, Iskusnykh, Igor, Chizhikov, Viktor, Scoggins, Matthew, Zhang, Silu, Edwards, Angela, Deng, Mei, Glass, Ian, Overman, Lynne, Millman, Jake, Sjoboen, Alexandria, Hadley, Jennifer, Mankad, Kshitij, Onar-Thomas, Arzu, Gajjar, Amar, Robinson, Giles, Aldinger, Kimberly, Hovestadt, Volker, Tillman, Heather, Orr, Brent, Patay, Zoltán, Millen, Kathleen, Northcott, Paul

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MEDB-74. Serial assessment of measurable residual disease in medulloblastoma liquid biopsies von Northcott, Paul, Smith, Kyle, Kumar, Rahul, Paul, Leena, Bihannic, Laure, Lin, Tong, Maass, Kendra, Pajtler, Kristian, Chintagumpala, Murali, Su, Jack, Bouffet, Eric, Fisher, Michael, Gururangan, Sridharan, Cohn, Richard, Hassall, Tim, Hansford, Jordan, Klimo, Paul, Boop, Frederick, Stewart, Clinton, Harreld, Julie, Merchant, Thomas, Tatevossian, Ruth, Neale, Geoffrey, Lear, Matthew, Klco, Jeffery, Orr, Brent, Ellison, David, Gilbertson, Richard, Onar-Thomas, Arzu, Gajjar, Amar, Robinson, Giles

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Communication transforms the impact of the COVID‐19 pandemic on children with cancer and their families von Ferrara, Gia, Aguina, Molly, Mirochnick, Emily, Wiphatphumiprates, Parima, Moreira, Daniel C., Sniderman, Elizabeth, Villegas, César A., Kaye, Erica C., Ragab, Iman, Maliti, Biemba, Naidu, Gita, Gassant, Pascale Y., Arce, Daniela, Arora, Ramandeep Singh, Alcasabas, Ana Patricia, Raza, Muhammad Rafie, Velasco, Pablo, Kambugu, Joyce, Vinitsky, Anna, Rodriguez Galindo, Carlos, Agulnik, Asya, Graetz, Dylan E., Laptsevich, Aliaksandra, Huang, Haiying, Silva, Luciana Nunes, Vasquez, Jacqueline Montoya, Rusmawatiningtyas, Desy, Bolous, Nancy S., Haidar, Cyrine E., Bihannic, Laure, da Bandeira, Diana Sa, Wang, Jade Xiaoqing, Li, Dongfang, Graca, Flavia, Vasilyeva, Aksana, Lesmana, Harry

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PDTM-32. RESOLVING MEDULLOBLASTOMA CELLULAR ARCHITECTURE BY SINGLE-CELL GENOMICS von Bihannic, Laure, Hovestadt, Volker, Smith, Kyle, Filbin, Mariella, Shaw, McKenzie, Baumgartner, Alicia, DeWitt, John, Groves, Andrew, Mayr, Lisa, Weisman, Hannah, Richman, Alyssa, Shore, Marni, Goumnerova, Liliana, Rosencrance, Celeste, Carter, Robert, Phoenix, Timothy, Hadley, Jennifer, Tong, Yiai, Houston, Jim, Ashmun, Richard, DeCuypere, Michael, Sharma, Tanvi, Ligon, Keith, Pomeroy, Scott, Rivera, Miguel, Rozenblatt-Rosen, Orit, Rusert, Jessica, Wechsler-Reya, Robert, Li, Xiao-Nan, Peyrl, Andreas, Gojo, Johannes, Kirchhofer, Dominik, Lötsch, Daniela, Czech, Thomas, Dorfer, Christian, Haberler, Christine, Geyeregger, Rene, Halfmann, Angela, Gawad, Charles, Easton, John, Pfister, Stefan, Regev, Aviv, Gajjar, Amar, Orr, Brent, Slavc, Irene, Robinson, Giles, Bernstein, Bradley, Suvà, Mario, Northcott, Paul

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CS-01 THE PHOSPHORYLATION OF ATOH1 LEADS TO ITS DEGRADATION MEDIATED BY THE E3 UBIQUITIN LIGASE HUWE1 IN GRANULE NEURON PROGENITORS von Bihannic, L., Forget, A., Cigna, S. M., Lefevre, C., Remke, M., Barnat, M., Dodier, S., Shirvani, H., Mercier, A., Mensah, A., Garcia, M., Humbert, S., Taylor, M. D., Lasorella, A., Ayrault, O.

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CS-01THE PHOSPHORYLATION OF ATOH1 LEADS TO ITS DEGRADATION MEDIATED BY THE E3 UBIQUITIN LIGASE HUWE1 IN GRANULE NEURON PROGENITORS von Bihannic, Laure, Forget, Antoine, Cigna, Sara Maria, Lefevre, Coralie, Remke, Marc, Barnat, Monia, Dodier, Sophie, Shirvani, Hamasseh, Mercier, Audrey, Mensah, Aurore, Garcia, Mickael, Humbert, Sandrine, Taylor, Michael D., Lasorella, Anna, Ayrault, Olivier

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