Recent Advances in the Treatment of Malignant Astrocytoma von Reardon, David A, Rich, Jeremy N, Friedman, Henry S, Bigner, Darell D

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Development of novel targeted therapies in the treatment of malignant glioma von Rich, Jeremy N, Bigner, Darell D

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Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma von FECCI, Peter E, MITCHELL, Duane A, WHITESIDES, John F, WEIHUA XIE, FRIEDMAN, Allan H, ARCHER, Gary E, HERNDON, James E, BIGNER, Darell D, DRANOFF, Glenn, SAMPSON, John H

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Gene expression profiling and genetic markers in glioblastoma survival von RICH, Jeremy N, HANS, Christopher, WEST, Mike, JONES, Beatrix, IVERSEN, Edwin S, MCLENDON, Roger E, RASHEED, B. K, DOBRA, Adrian, DRESSMAN, Holly K, BIGNER, Darell D, NEVINS, Joseph R

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Phase II Trial of Gefitinib in Recurrent Glioblastoma von Rich, Jeremy N, Reardon, David A, Peery, Terry, Dowell, Jeannette M, Quinn, Jennifer A, Penne, Kara L, Wikstrand, Carol J, Van Duyn, Lauren B, Dancey, Janet E, McLendon, Roger E, Kao, James C, Stenzel, Timothy T, Ahmed Rasheed, B K, Tourt-Uhlig, Sandra E, Herndon, 2nd, James E, Vredenburgh, James J, Sampson, John H, Friedman, Allan H, Bigner, Darell D, Friedman, Henry S

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Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas von BRODERICK, Daniel K, CHUNHUI DI, PARRETT, Timothy J, SAMUELS, Yardena R, CUMMINS, Jordan M, MCLENDON, Roger E, FULTS, Daniel W, VELCULESCU, Victor E, BIGNER, Darell D, HAI YAN

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Mutations of the BRAF gene in human cancer von Wooster, Richard, Davies, Helen, Bignell, Graham R, Cox, Charles, Stephens, Philip, Edkins, Sarah, Clegg, Sheila, Teague, Jon, Woffendin, Hayley, Garnett, Mathew J, Bottomley, William, Davis, Neil, Dicks, Ed, Ewing, Rebecca, Floyd, Yvonne, Gray, Kristian, Hall, Sarah, Hawes, Rachel, Hughes, Jaime, Kosmidou, Vivian, Menzies, Andrew, Mould, Catherine, Parker, Adrian, Stevens, Claire, Watt, Stephen, Hooper, Steven, Wilson, Rebecca, Jayatilake, Hiran, Gusterson, Barry A, Cooper, Colin, Shipley, Janet, Hargrave, Darren, Pritchard-Jones, Katherine, Maitland, Norman, Chenevix-Trench, Georgia, Riggins, Gregory J, Bigner, Darell D, Palmieri, Giuseppe, Cossu, Antonio, Flanagan, Adrienne, Nicholson, Andrew, Ho, Judy W. C, Leung, Suet Y, Yuen, Siu T, Weber, Barbara L, Seigler, Hilliard F, Darrow, Timothy L, Paterson, Hugh, Marais, Richard, Marshall, Christopher J, Stratton, Michael R, Futreal, P. Andrew

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EGF mutant receptor vIII as a molecular target in cancer therapy von Kuan, C T, Wikstrand, C J, Bigner, D D

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PTEN gene mutations are seen in high-grade but not in low-grade gliomas von AHMED RASHEED, B. K, STENZEL, T. T, MCLENDON, R. E, PARSONS, R, FRIEDMAN, A. H, FRIEDMAN, H. S, BIGNER, D. D, BIGNER, S. H

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Glycoprotein Nonmetastatic Melanoma Protein B, a Potential Molecular Therapeutic Target in Patients with Glioblastoma Multiforme von KUAN, Chien-Tsun, WAKIYA, Kenji, DOWELL, Jeannette M, HERNDON, James E, REARDON, David A, GRANER, Michael W, RIGGINS, Gregory J, WIKSTRAND, Carol J, BIGNER, Darell D

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Molecular Genetic Aspects of Oligodendrogliomas Including Analysis by Comparative Genomic Hybridization von Bigner, Sandra H., Matthews, Mark R., Rasheed, B.K.A., Wiltshire, Rodney N., Friedman, Henry S., Friedman, Allan H., Stenzel, Timothy T., Dawes, Donald M., McLendon, Roger E., Bigner, Darell D.

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Salvage Radioimmunotherapy With Murine Iodine-131–Labeled Antitenascin Monoclonal Antibody 81C6 for Patients With Recurrent Primary and Metastatic Malignant Brain Tumors: Phase II... von REARDON, David A, AKABANI, Gamal, RICH, Jeremy N, VREDENBURGH, James J, DESJARDINS, Annick, GURUANGAN, Sri, BADRUDDOJA, Michael, DOWELL, Jeanette M, WONG, Terence Z, ZHAO, Xiao-Guang, ZALUTSKY, Michael R, BIGNER, Darell D, COLEMAN, R. Edward, FRIEDMAN, Allan H, FRIEDMAN, Henry S, HERNDON, James E, MCLENDON, Roger E, PEGRAM, Charles N, PROVENZALE, James M, QUINN, Jennifer A

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Phase 1 Trial of Gefitinib Plus Sirolimus in Adults with Recurrent Malignant Glioma von REARDON, David A, QUINN, Jennifer A, PROVENZALE, James M, SAMPSON, John H, SMITH, Robert P, SWAISLAND, Alan J, OCHS, Judith S, LYONS, Peggy, TOURT-UHLIG, Sandy, BIGNER, Darell D, FRIEDMAN, Henry S, RICH, Jeremy N, VREDENBURGH, James J, GURURANGAN, Sridharan, FRIEDMAN, Allan H, DESJARDINS, Annick, SATHORNSUMETEE, Sith, HERNDON, James E, DOWELL, Jeannette M, MCLENDON, Roger E

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Epidermal Growth Factor Receptor VIII Peptide Vaccination Is Efficacious against Established Intracerebral Tumors von HEIMBERGER, Amy B, CROTTY, Laura E, ARCHER, Gary E, HESS, Kenneth R, WIKSTRAND, Carol J, FRIEDMAN, Allan H, FRIEDMAN, Henry S, BIGNER, Darell D, SAMPSON, John H

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Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers i... von Goudar, Ranjit K, Shi, Qing, Hjelmeland, Mark D, Keir, Stephen T, McLendon, Roger E, Wikstrand, Carol J, Reese, Elizabeth D, Conrad, Charles A, Traxler, Peter, Lane, Heidi A, Reardon, David A, Cavenee, Webster K, Wang, Xiao-Fan, Bigner, Darell D, Friedman, Henry S, Rich, Jeremy N

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Elevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer von Xie, Liyi, Lin, Chen, Zhang, Qingfu, Piao, Hailan, Bigner, Darell D, Zhang, Zhen, Bao, Xuhui

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SB-431542, a small molecule transforming growth factor-β-receptor antagonist, inhibits human glioma cell line proliferation and motility von Hjelmeland, Mark D, Hjelmeland, Anita B, Sathornsumetee, Sith, Reese, Elizabeth D, Herbstreith, Michael H, Laping, Nicholas J, Friedman, Henry S, Bigner, Darell D, Wang, Xiao-Fan, Rich, Jeremy N

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Resistance to Tyrosine Kinase Inhibition by Mutant Epidermal Growth Factor Receptor Variant III Contributes to the Neoplastic Phenotype of Glioblastoma Multiforme von LEARN, Chris A, HARTZELL, Tristan L, WIKSTRAND, Carol J, ARCHER, Gary E, RICH, Jeremy N, FRIEDMAN, Allan H, FRIEDMAN, Henry S, BIGNER, Darell D, SAMPSON, John H

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Phase II Trial of Temozolomide in Patients With Progressive Low-Grade Glioma von QUINN, Jennifer A, REARDON, David A, AVGEROPOULOS, Nicholas, FINLAY, Jonathan, TOURT-UHLIG, Sandra, AFFRONTI, Mary Lou, EVANS, Brandon, STAFFORD-FOX, Valerie, ZAKNOEN, Sara, FRIEDMAN, Henry S, FRIEDMAN, Allan H, RICH, Jeremy N, SAMPSON, John H, PROVENZALE, James M, MCLENDON, Roger E, GURURANGAN, Sridharan, BIGNER, Darell D, HERNDON, James E

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Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair–deficient malignant glioma xenograft von Cheng, C Lynn, Johnson, Stewart P, Keir, Stephen T, Quinn, Jennifer A, Ali-Osman, Francis, Szabo, Csaba, Li, Hongshan, Salzman, Andrew L, Dolan, M Eileen, Modrich, Paul, Bigner, Darell D, Friedman, Henry S

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